TH96569A - The derivative compound is derived from Pyrimidine, a kinase, Aurora inhibitor. - Google Patents
The derivative compound is derived from Pyrimidine, a kinase, Aurora inhibitor.Info
- Publication number
- TH96569A TH96569A TH701002345A TH0701002345A TH96569A TH 96569 A TH96569 A TH 96569A TH 701002345 A TH701002345 A TH 701002345A TH 0701002345 A TH0701002345 A TH 0701002345A TH 96569 A TH96569 A TH 96569A
- Authority
- TH
- Thailand
- Prior art keywords
- pyrimidine
- kinase
- derived
- derivative compound
- aurora inhibitor
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- CZPWVGJYEJSRLH-UHFFFAOYSA-N 289-95-2 Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 102000030951 Phosphotransferases Human genes 0.000 title 1
- 108091000081 Phosphotransferases Proteins 0.000 title 1
- 239000005441 aurora Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
Abstract
DC60 (01/08/50) การประดิษฐ์นี้ครอบคลุมสารประกอบของสูตรทั่วไป (1) (สูตรเคมี) (1) ซึ่ง R1,R2,R4,R6, X, m, n และ p นิยามตามข้อถือสิทธิข้อ 1, ซึ่งเหมาะสมสำหรับการบำบัด โรคที่จำแนกเอกลักษณ์โดยการเพิ่มจำนวนของเซลล์ที่มากเกินหรือผิดปกติ, และการใช้เพื่อการเตรียม องค์ประกอบทางเภสัชวิทยาที่มีสมบัติที่กล่าวข้างบนนี้ การประดิษฐ์นี้ครอบคลุมสารประกอบของสูตรทั่วไป (1) (สูตรเคมี) (1) ซึ่ง R1,R2,R4,R6, X, m, n และ p นิยามตามข้อถือสิทธิข้อ 1, ซึ่งเหมาะสมสำหรับการบำบัด โรคที่จำแนกเอกลักษณ์โดยการเพิ่มจำนวนของเซลล์ที่มากเกินหรือผิดปกติ, และการใช้เพื่อการเตรียม องค์ประกอบทางเภสัชวิทยาที่มีสมบัติที่กล่าวข้างบนนี้ สิทธิบัตรยา DC60 (01/08/50) This invention covers compounds of the general formula (1) (chemical formula) (1), where R1, R2, R4, R6, X, m, n and p are defined according to claim 1, which Suitable for therapy Diseases characterized by excess or abnormal cell proliferation, and use for preparation Pharmacological components with the properties mentioned above. This invention covers compounds of general formulas (1) (chemical formulas) (1), in which R1, R2, R4, R6, X, m, n and p are defined according to claim 1, which are suitable for therapy. Diseases characterized by excess or abnormal cell proliferation, and use for preparation Pharmacological components with the properties mentioned above.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH96569A true TH96569A (en) | 2009-07-09 |
| TH96569B TH96569B (en) | 2009-07-09 |
Family
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