TH83577A - Amino-Imidazolone For inhibition of B-zecretase - Google Patents
Amino-Imidazolone For inhibition of B-zecretaseInfo
- Publication number
- TH83577A TH83577A TH601000111A TH0601000111A TH83577A TH 83577 A TH83577 A TH 83577A TH 601000111 A TH601000111 A TH 601000111A TH 0601000111 A TH0601000111 A TH 0601000111A TH 83577 A TH83577 A TH 83577A
- Authority
- TH
- Thailand
- Prior art keywords
- amino
- formula
- beta
- zecretase
- imidazolone
- Prior art date
Links
- ZMLJHXQHPNGPJP-UHFFFAOYSA-N 4-aminoimidazol-2-one Chemical compound NC1=NC(=O)N=C1 ZMLJHXQHPNGPJP-UHFFFAOYSA-N 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atoms Chemical group 0.000 claims 1
- 125000005842 heteroatoms Chemical group 0.000 claims 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 2
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 2
- 101700044176 BACE Proteins 0.000 abstract 2
- 101700051112 BACE1 Proteins 0.000 abstract 2
- 102100015650 BACE1 Human genes 0.000 abstract 2
- 210000001682 Neurofibril Anatomy 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
Abstract
DC60 (29/03/49) การประดิษฐ์นี้จะจัดให้มีสารประกอบอะมิโน-อะมิดาโซโลน ที่มีสูตร I (สูตรเคมี) (I) ที่ถูกจัดให้มีอีกด้วย คือ สารผสม และวิธีการ สำหรับการใช้ของสิ่งเหล่านี้ เพื่อยับยั้ง เบตา-ซีครีเตส (BACE) และบำบัดรักษาการตกสะสมของ เบตา-อะไมลอยด์ และ การพันกันของนิวโรไฟบริล การประดิษฐ์นี้จะจัดให้มีสารประกอบอะมิโน-อะมิดาโซโลน ที่มีสูตร I (สูตรเคมี) (I) ที่ถูกจัดให้มีอีกด้วย คือ สารผสม และวิธีการ สำหรับการใช้ของสิ่งเหล่านี้ เพื่อยับยั้ง เบตา-ซีครีเตส (BACE) และบำบัดรักษาการตกสะสมของ เบตา-อะไมลอยด์ และ การพันกันของนิวโรไฟบริล สิทธิบัตรยา DC60 (29/03/49) This invention provides an amino-amidazolone compound with the formula I (chemical formula) (I) that is also provided, a mixture and a method for the Use of these to inhibit beta-sequestrate (BACE) and to treat Beta-amyloid and neurofibril tangles The invention will also provide amino-amidazolone compounds with formula I (chemical formula) (I) that are also provided, mixtures and methods for their use to inhibit beta. - Cecretase (BACE) and treatment of accumulation of Beta-amyloid and neurofibril tangles.Patent of drug.
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH83577B TH83577B (en) | 2007-03-15 |
TH83577A true TH83577A (en) | 2007-03-15 |
Family
ID=
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2009008772A (en) | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process. | |
TH83577A (en) | Amino-Imidazolone For inhibition of B-zecretase | |
TH83577B (en) | Amino-Imidazolone For the inhibition of B-Zecretase | |
TH94707A (en) | Amino-5- (4- (diffluoromethoxi) phenyl] -5-phenylimidazolone for the inhibition of B zecretase. | |
TH94707B (en) | Amino-5- (4- (diffluoromethoxi) phenyl] -5-phenylimidazolone for the inhibition of B zecretase | |
TH86425A (en) | 2,4-diamino-pirimidine In the form of an aurora inhibitor | |
EA200970812A1 (en) | METHOD OF TREATMENT AND PREVENTION OF ARTHRITIS | |
TH81544B (en) | Diphenyl, Imidazopyrimidine and -imidazole amine as inhibitors of Beta-Sea Cretace | |
TH86425B (en) | 2,4-diamino-pirimidine In the form of an aurora inhibitor | |
TH80768B (en) | Quinoline derivatives, production use and pharmaceutical substances of such substances with a back | |
TH93357B (en) | Amino-Imidazoline And their use as a drug for the treatment of cognitive impairment, Alzheimer's disease, neurodegeneration. And dementia | |
TH86644A (en) | Derivatives of 5-piridazyl-1-azabycloid [3.2.1] octane, preparation of the substance and its therapeutic use. | |
TH96070A (en) | Tetrahydropyridothienotyimidine Compound And how to use them | |
TH83173A (en) | Chemical compound | |
TH93357A (en) | Amino-Imidazoline And their use as a drug for the treatment of cognitive impairment, Alzheimer's disease, neurodegeneration. And dementia | |
TH62190A (en) | Organic compounds | |
TH86644B (en) | Derivatives of 5-piridazyl-1-azabycloid [3.2.1] octane, preparation and use of it. | |
TH95367B (en) | Amino-Imidazoline And their use as a drug for the treatment of cognitive impairment, Alzheimer's disease, neurodegeneration. And dementia | |
TH84734B (en) | Thyacine derivatives Preparation And the use of that substance in the treatment of disease | |
TH87472B (en) | compound | |
TH82909B (en) | Compounds for inhibiting the activity of KSP kinzine | |
TH84734A (en) | Thyacine derivatives Preparation And the use of that substance in the treatment of disease | |
TH95367A (en) | Amino-Imidazoline And their use as a drug for the treatment of cognitive impairment, Alzheimer's disease, neurodegeneration. And dementia | |
TH103349A (en) | Imidazoacetone compound | |
TH87496B (en) | New compound |