TH76489A - Bundling of calcium-containing compounds by roller compacting - Google Patents

Abstract

DC60 (18/10/56) Particular material fabrication And solid drug forms, especially the tablets that contain With a uniform calcium-containing compound such as calcium salt as an active therapeutic and / or therapeutic ingredient and a pharmaceutical sugar alcohol, for example, sorbitol and / or isomol. As demonstrated by SEM, the invention also About the process for the preparation of particle materials And solid dosage forms The process involves Include groups of calcium-containing compounds And sugar alcohols that are accepted by pharmaceuticals Compacting with rollers Roller compacted partition material is suitable for use in Further processes of the parthicylate material are performed, for example, tablets such as chewable tablets

Claims (1)

1. : DC60 (18/10/56) The invention relates to particulate materials and solid dosage forms, particularly tablets, comprising a uniformly shaped calcium-containing compound, such as a therapeutic and/or medicinally active calcium salt, and a pharmaceutically acceptable sugar alcohol such as, for example, sorbitol and/or isomalt, having a microstructure as demonstrated by SEM. The invention also relates to a process for preparing particulate materials and solid dosage forms. The process involves the agglomeration of the calcium-containing compound and a pharmaceutically acceptable sugar alcohol by means of roller compaction. The roller compaction particulate material is suitable for use in further processing the particulate material into, for example, tablets, such as chewable tablets. Claim (one) appears on the advertisement page: Tags: