TH2003002804C3 - Protein hydrolyzate chewable tablet formulation and manufacturing method - Google Patents

Abstract

The invention is to develop a protein hydrolyzate chewable tablet formulation containing the following ingredients: Hydrolyzate egg white protein powder Binders for punching tablets Polyvinylpyrolidone K-30 (TVPK-30) (POLYVINYL?PYRROLIDONE K-30; PVP K-30), sucralose, xylitol, magnesium stearate and powder, flavors or flavors. There is a production process, the steps are as follows. Prepare wet granulation by pulverizing egg white hydrolyzate protein powder and binder into a homogeneous mixture. Bring it wet and then bake it with a hot air oven. Then dried with a shaker. The dry granules were then mixed with sucralose and xylitol. Mix until homogeneous. Add flavor powder or satie flavor and add magnesium stearate lubricant, mix well Then bring the tablets. The product will be a protein hydrolyzate chewable tablet product that looks smooth, does not break, is a healthy food. Improves nutritional value in the food and pharmaceutical industry ------------ This invention is to develop a protein hydrolyzate chewable tablet formulation containing the following ingredients: Egg white protein powder, hydrolysate, pill binder, PVP K-30 (PVP K-30), sucralose, xylitol, magnesium stearate and flavor powder. There is a production process, the steps are as follows. Prepare to make wet granulation by grinding the egg white protein powder. Hydrolyzate and binder homogeneous Bring it wet and then bake it with a hot air oven. Then bring it to dry. with a shaker The dry granules were then mixed with sucralose and xylitol. Mix until homogeneous, add powder, flavor or taste. and add magnesium stearate lubricant, mix well Then crushed into tablets to produce protein hydrolyzate chewable tablets that are smooth and not chipped. It is a healthy food that helps increase nutritional value in the food and pharmaceutical industry.

Claims (2)

1. Protein Hydrolyzate Chewable Tablet Formula Contains the following ingredients: - Egg white hydrolyzate protein powder 83.21 percent by weight - Tablet binder 0.60 percent by weight Polyvinylpyrolidone K-30 (PVP K-30) (POLYVINYL PYRROLIDONE K-30; PVP K-30) - Sucralose (Sucralose) 0.1 wt% - Xylitol (sorbitol ) 14 percent by weight - Flavor Powder or Flavor Powder 1.86 percent by weight - Magnesium Stearate 0.23 percent by weight2. Production process for protein hydrolyzate chewable tablets According to the claim 1. Where the steps are as follows: a. Prepare wet granulation. By bringing the hydrolyzed egg white protein powder to be ground and mixed with the binder to press the tablet. Polyvinylpyrolidone K-30 (PVP K-RO) (POLYVINYL PYRROLIDONE K-30; PVP K-30) in tiles Grind and mix the drug until the substance is well dispersed and homogeneous, then gradually pour 80 ml of 99.80% pure ethyl alcohol into it and mix continuously. Until all substances are wet and the ingredients are mixed well, then wet the granules by using a sieve shaker No. 20 to get wet granules b. Dry the wet granules obtained from step a. in a cabinet. Dry in hot air at 50 °C for 1 hour or until the granules are dry. After that, the granules were dried with a sieve shaker No. 16 to obtain dry granules with a particle size of not more than 1.20 mm and to reduce dust formation. Pass through sieve No. 40, then sucralose and flavor powder or flavor powder are passed through a sieve No. 40 shaker. from step c in a plastic bag (a transparent hot bag, large and with enough space to allow the granules to roll and mix well) for 1 min, then the xylitol obtained from step c is added. E. Take the dry granules obtained from item D. Add the aroma powder or satiety powder obtained from item C. and mix them together with a V-shaped mixer. for 1 minute, then added magnesium stearate lubricant and mixed thoroughly with a V-shaped mixer for 3 minutes before pelletizing by direct compression method to get the final product. Protein hydrolyzate chewable tablets with flavor powder or flavor powder ------------ 1. Protein Hydrolyzate Chewable Tablet Formula Contains the following ingredients -Egg white hydrolysate protein powder 83.21 percent by weight - Binder for punching tablets PVP K-30 (PVP K-30) 0.60 percent by weight - Sucralose (sucralose) 0.1 percent by weight - Xylitol (sorbitol) 14 percent by weight - Flavor powder or flavor powder 1.86 percent by weight - Magnesium Stearate 0.23 percent by weight 2. Manufacturing process of protein hydrolyzate chewable tablets There are steps as follows: a. Prepare wet granulation. By bringing the hydrolyzed egg white protein powder to be ground and mixed with the binder for punching the PVP K-30 tablets (PVP K-30) in the tiles. Grind and mix the drug until the substance is well dispersed and homogeneous, then slowly pour 80 ml of 99.80% pure ethyl alcohol into it and mix continuously. Until all substances are wet and the ingredients are well mixed, then wet using a shaker. Sieve No. 20 will produce wet granules. B. Dry granules obtained from step A in a hot air oven at 50 °C for 1 hour or until the granules are dry. After that, the granules were dried with a sieve shaker No. 16 to obtain dry granules that were Particle size not exceeding 1.20 mm. and reducing the generation of dust. 40 d. The dry granules obtained from step B were mixed with the sucralose obtained from step c in a plastic bag (a transparent hot bag, large size and containing enough space to allow the granules to roll and mix well) for 1 min. Then add the xylitol sugar obtained from step c. and mix thoroughly for 1 min. E. Remove the granules. Add the flavor powder or flavor powder obtained from item C and mix well. V-mixer for 1 min, then add magnesium stearate lubricant and mix well. V-shaped mixer for 3 minutes before being pelletized by direct compression to produce protein hydrolyzate chewable tablets with flavor or fruit flavors.