TH167679B - Nucleic acid molecules, which encode the hepatitis B core protein. And proteins, surface antigens, and vaccines, which are made up of the same - Google Patents
Nucleic acid molecules, which encode the hepatitis B core protein. And proteins, surface antigens, and vaccines, which are made up of the sameInfo
- Publication number
- TH167679B TH167679B TH1501001459A TH1501001459A TH167679B TH 167679 B TH167679 B TH 167679B TH 1501001459 A TH1501001459 A TH 1501001459A TH 1501001459 A TH1501001459 A TH 1501001459A TH 167679 B TH167679 B TH 167679B
- Authority
- TH
- Thailand
- Prior art keywords
- vaccines
- nucleic acid
- hepatitis
- encode
- proteins
- Prior art date
Links
- 229960005486 vaccines Drugs 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 102000038129 antigens Human genes 0.000 title abstract 2
- 108091007172 antigens Proteins 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 208000002672 Hepatitis B Diseases 0.000 title 1
- 102000018697 Membrane Proteins Human genes 0.000 title 1
- 108010052285 Membrane Proteins Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 230000028993 immune response Effects 0.000 abstract 2
- 210000004185 Liver Anatomy 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000002440 hepatic Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003834 intracellular Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic Effects 0.000 abstract 1
Abstract
สิ่งที่จัดให้มีขึ้นในคำขอนี้คือโมเลกุลกรดนิวคลีอิกซึ่งเข้ารหัสโปรตีนแกนกลางไวรัสตับ อีกเสบชนิดบี (HBV), โปรตีนแอนติเจนที่พื้นผิว, ชิ้นส่วนและการรวมกันของสิ่งนั้นรวมทั้ง โครงสร้าง/เวกเตอร์และวัคซีนที่แสดงออกลำดับโปรตีนดังกล่าว วัคซีนเหล่านี้สามารถชักนำการ ตอบสนองทางภูมิคุ้มกันที่ส่วนขอบและในตับโดยการจัดหาสารในเซลล์และสารน้ำ รวมถึงจัดหา วิธีการสำหรับการก่อภูมิคุ้มกันเชิงการป้องกันโรคและ/หรือการรักษาโรคเฉพาะรายต้าน HBV การ รวมกันของวัคซีนยังสามารถใช้สำหรับการออกแบบวัคซีนเฉพาะสำหรับระดับเฉพาะของการ ตอบสนองทางภูมิคุ้มกันต่อความท้าทายของ HBV Provided in this request is a nucleic acid molecule which encodes another hepatic virus core B (HBV) protein, surface antigen protein, its fragments and combinations thereof, including Structures / vectors and vaccines expressing such protein sequences. These vaccines can induce Immune response at the margins and in the liver by supplying intracellular and fluid substances as well as providing a means for prophylactic and / or therapeutic immunization against HBV. Combinations of vaccines can also be used. For designing a specific vaccine for a specific level of Immune response to the challenge of HBV
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH167679B true TH167679B (en) | 2017-09-07 |
| TH167679A TH167679A (en) | 2017-09-07 |
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