TH170760A - Broad-spectrum reactive antigens calculated optimization for H1N1 influenza. - Google Patents
Broad-spectrum reactive antigens calculated optimization for H1N1 influenza.Info
- Publication number
- TH170760A TH170760A TH1501002843A TH1501002843A TH170760A TH 170760 A TH170760 A TH 170760A TH 1501002843 A TH1501002843 A TH 1501002843A TH 1501002843 A TH1501002843 A TH 1501002843A TH 170760 A TH170760 A TH 170760A
- Authority
- TH
- Thailand
- Prior art keywords
- polypeptide
- appropriate
- influenza
- immune response
- influenza virus
- Prior art date
Links
- 206010069767 H1N1 influenza Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000038129 antigens Human genes 0.000 title 1
- 108091007172 antigens Proteins 0.000 title 1
- 238000005457 optimization Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 claims abstract 9
- 230000028993 immune response Effects 0.000 claims abstract 4
- 241000712461 unidentified influenza virus Species 0.000 claims abstract 4
- 206010022000 Influenza Diseases 0.000 claims abstract 2
- 229920001850 Nucleic acid sequence Polymers 0.000 claims abstract 2
- 239000000470 constituent Substances 0.000 claims abstract 2
- 230000000875 corresponding Effects 0.000 claims abstract 2
- 150000007523 nucleic acids Chemical group 0.000 claims abstract 2
- 238000000734 protein sequencing Methods 0.000 claims abstract 2
- 108090000623 proteins and genes Proteins 0.000 claims abstract 2
- 102000004169 proteins and genes Human genes 0.000 claims abstract 2
- 230000004936 stimulating Effects 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
Abstract
คำขอใหม่ปรับปรุงวันที่ 23/02/2559 ที่อธิบายในที่นี้คือการสร้างพอลีเพบไทด์ของไข้หวัดใหญ่ H1N1 HA ที่เหมาะสมสำหรับการ กระตุ้นการตอบสนองของภูมิคุ้มกันต่อไวรัสไข้หวัดใหญ่ H1N1 พอลีเพบไทด์ HA ที่เหมาะสมถูก พัฒนาขึ้นผ่านลำดับการเรียงตัวของโปรตีน HA และการเกิดลำดับที่สอดคล้องกับ ขึ้นอยู่กับไวรัส H1N1 ที่ ถูกเลือกจาก 1918-2012 ถูกจัดให้มีในที่นี้คือพอลีเพบไทด์ HA H1N1 ที่เหมาะสม และส่วนประกอบ, การ รวมกันของโปรตีน และ VLP ประกอบรวมด้วยพอลีเพบไทด์ HA นอกจากนี้จัดให้มีลำดับกรดนิวคลีอิก โคดอนที่เหมาะสมที่เข้ารหัสพอลีเพบไทด์ HA วิธีการของการกระตุ้นการตอบสนองของภูมิคุ้มกันต่อ ไวรัสไข้หวัดใหญ่ได้ถูกจัดให้มีเช่นกันในการเปิดเผยนี้ สิทธิบัตรยา The new request, update 23/02/2016 described here is to create a suitable H1N1 HA flu peptide for Stimulate the immune response to influenza virus H1N1, the appropriate HA polypeptide was Developed through HA protein sequencing and sequencing corresponding to Based on the H1N1 virus selected from 1918-2012, it is provided here as an appropriate HA H1N1 polypeptide and its constituents, protein and VLP combination, containing HA polypeptide. In addition, it provides a nucleic acid sequence. Appropriate codons encoding the HA polypeptide, a method of stimulating the immune response against The influenza virus was also made available in this disclosure.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH170760A true TH170760A (en) | 2017-11-23 |
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