TH151381A - Heterocyclic derivatives New Heterocyclic Derivatives and Their Applications in the Treatment of Neurological Disorders - Google Patents
Heterocyclic derivatives New Heterocyclic Derivatives and Their Applications in the Treatment of Neurological DisordersInfo
- Publication number
- TH151381A TH151381A TH1301003911A TH1301003911A TH151381A TH 151381 A TH151381 A TH 151381A TH 1301003911 A TH1301003911 A TH 1301003911A TH 1301003911 A TH1301003911 A TH 1301003911A TH 151381 A TH151381 A TH 151381A
- Authority
- TH
- Thailand
- Prior art keywords
- bace
- treatment
- formula
- heterocyclic derivatives
- new
- Prior art date
Links
- 125000000623 heterocyclic group Chemical group 0.000 title 2
- 208000009025 Nervous System Disease Diseases 0.000 title 1
- 206010029305 Neurological disorder Diseases 0.000 title 1
- 206010012601 Diabetes mellitus Diseases 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 4
- 230000002401 inhibitory effect Effects 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 206010001897 Alzheimer's disease Diseases 0.000 claims abstract 2
- 206010029331 Neuropathy peripheral Diseases 0.000 claims abstract 2
- 239000003795 chemical substances by application Substances 0.000 claims abstract 2
- 239000000470 constituent Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 claims abstract 2
- 201000001119 neuropathy Diseases 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Abstract
DC60 (10/10/56) การประดิษฐ์เกี่ยวข้องกับสารประกอบเฮทเทอโรไซคลิก (heteroctlicy) ตัวใหม่ ตาม สูตร (I), ที่ซึ่งตัวเเปรทั้งหมดคือดังที่ถูกนิยามไว้ในรายละเอียด, องค์ประกอบเชิงเภสัชกรรมของ พวกมัน, การร่วมกันของพวกมัน, เเละการใช้งานพวกมันโดยเป็นเวชภัณฑ์, โดยเฉพาะ สำหรับ การบำบัดโรคอัลไซเมอร์หรือโรคเบาหวาน โดยผ่านการยับยั้งของ BACE-1 หรือ BACE-2 (สูตรเคมี) (I), การประดิษฐ์เกี่ยวข้องกับสารประกอบเฮทเทอรโรไซคลิก(heteroctlicy)ตัวใหม่ ตาม สูตร(I)ที่ซึ่งตัวเเปรทั้งหมดคือดังที่ถูกนิยามไว้ในละเอียด องค์ประกอบเชิงเภสัใชกรรมของ พวกมัน การร่วมกันของพวกมัน เเละการใช้งานพวกมันโดยเป็นเวชภัณฑ์ โดยเฉพาะ สำหรับ การบำบัดโรคไซเมอร์หรือโรคเบาหวาน โดยผ่านการยับยั้งของ BACE-1 หรือ BACE-2 สิทธิบัตรยา DC60 (10/10/56), the invention involved heterocyclic compounds. The new heteroctlicy follows the formula (I), where all agents are, as defined in detail, their pharmaceutical constituents, their combination, and their use as Pharmaceuticals, especially for the treatment of Alzheimer's disease or diabetes Through the inhibition of BACE-1 or BACE-2 (chemical formula) (I), the invention involved a new heteroctlicy (I) compound based on the formula (I), where all the samples were, as Is defined in detail Their interchangeable elements, their combination And the use of them as medical supplies specifically for the treatment of neuropathy or diabetes. Through the inhibition of BACE-1 or BACE-2 drug patents
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH151381A true TH151381A (en) | 2016-05-31 |
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