TH137158B - Antiviral compounds - Google Patents
Antiviral compoundsInfo
- Publication number
- TH137158B TH137158B TH901005662A TH0901005662A TH137158B TH 137158 B TH137158 B TH 137158B TH 901005662 A TH901005662 A TH 901005662A TH 0901005662 A TH0901005662 A TH 0901005662A TH 137158 B TH137158 B TH 137158B
- Authority
- TH
- Thailand
- Prior art keywords
- antiviral compounds
- formula
- hcv
- alkyl
- hydrogen
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 3
- 230000000840 anti-viral Effects 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 2
- 150000001204 N-oxides Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 241000711549 Hepacivirus C Species 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940042399 direct acting antivirals Protease inhibitors Drugs 0.000 abstract 1
- 201000009910 diseases by infectious agent Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Abstract
การประดิษฐ์เกี่ยวข้องกับสารประกอบแมคโครไซคลิกของสูตร (I) ที่เป็นประโยชน์ใน ฐานะตัวยับยั้ง NS3 โปรตีเอสของไวรัสตับอักเสบ C (HCV), การสังเคราะห์สารเหล่านั้น และ การ ใช้สารเหล่านั้นสำหรับการบำบัด หรือ การป้องกันการติดเชื้อ HCV (สูตร) The invention involved a compound of formula (I) that is useful in As NS3 protease inhibitors of hepatitis C virus (HCV), synthesis of those substances and the use of them for the therapy or prevention of HCV infection (formulation).
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH137158A TH137158A (en) | 2014-10-08 |
| TH137158B true TH137158B (en) | 2014-10-08 |
Family
ID=
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