SU858829A1

SU858829A1 - Method of treating virus hepatitis

Info

Publication number: SU858829A1
Application number: SU782693245A
Authority: SU
Inventors: Валентин Ефимович Рычнев; Валерий Митрофанович Фролов; Петр Алексеевич Желтухин; Галина Андреевна Шелковская; Светлана Ивановна Шлыкова
Original assignee: Воронежский Государственный Медицинский Институт Им Н.И.Бурденко
Priority date: 1978-12-06
Filing date: 1978-12-06
Publication date: 1981-08-30

Description

Изобретение относится к медицине и касается терапии инфекционных заболеваний, а именно лечения вирусного гепатита.The invention relates to medicine and relates to the treatment of infectious diseases, namely the treatment of viral hepatitis.

Известен способ лечения вирусного гепатита диетой и витаминами DJ· $There is a method of treating viral hepatitis with diet and vitamins DJ · $

Однако лечение известным способом длительно.However, the treatment in a known manner is long.

Цель изобретения - сокращение сроков лечения.The purpose of the invention is the reduction of treatment time.

Указанная цель достигается тем, что в способе лечения вирусного гепатита, осуществляемом диетой и витаминами, одновременно проводят внутриректальную оксигенатерапию в дозе 500-1200 мл и вводят нуклеинат натрия *⁵в дозе 1,5-1,0 г.This goal is achieved by the fact that in the method of treating viral hepatitis by diet and vitamins, intrarectal oxygen therapy at a dose of 500-1200 ml is simultaneously administered and sodium nucleinate * ⁵ is administered at a dose of 1.5-1.0 g.

Больным вирусным гепатитом кроме лечения диетой проводят лечение нуклеинатом натрия- по 0,5 г три раза в день внутрь, внутриректальную ²⁰оксигенотерапию, витамин B^j- (паигамат кальция) по 0,05 г три раза в день.In addition to diet treatment, patients with viral hepatitis are treated with sodium nucleinate - 0.5 g three times a day by mouth, intrarectal ²⁰ oxygen therapy, vitamin B ^ j- (calcium paigamate) 0.05 g three times a day.

Нуклеинат натрия назначают в виде порошка внутрь по 0,5 г три раза в день после еды. При легком и среднетяжелом течении гепатита лечение продолжают 10 дней (15 г нуклеината натрия на курс), при тяжелом течении препарат назначают на 14 дней (21 г нуклеината натрия на курс).Sodium nucleinate is prescribed in the form of a powder inside of 0.5 g three times a day after meals. In mild and moderate hepatitis, treatment is continued for 10 days (15 g of sodium nucleinate per course), in severe cases, the drug is prescribed for 14 days (21 g of sodium nucleinate per course).

Внутриректальную оксигенотерапию производят ежедневно утром натощак после очистительной клизмы с помощью тонкого безоливного зонда. Дозировку кислорода осуществляют с помощью аппарата для наложения искусственного пневмоторакса. Зонд вводят в прямую кишку на глубину 10-15 см и в положении больного на левом боку / ему вводят кислород в кишечник. В первый день он получает 500 мл кислорода, в дальнейшем ежедневно прибавляют по 100 мл, т.е. на второй день получает 600 мл, на третий - 700 мл, четвертый - 800 мл, пятый - 900 мл, шестой - 1000 мл, седьмой - 1100 мл, восьмой - 1200 мл. С восьмого дня и до конца курса лечения больной получает 1200 мл кислорода ежедневно. Курс продолжается 10 дней при легком и среднетяжелом течении гепатита и 14 дней - при тяжелом течении заболевания.Intrarectal oxygen therapy is performed daily in the morning on an empty stomach after a cleansing enema using a thin non-irrigation probe. Dosage of oxygen is carried out using an apparatus for applying artificial pneumothorax. The probe is inserted into the rectum to a depth of 10-15 cm and in the patient’s position on the left side / oxygen is introduced into the intestine. On the first day, he receives 500 ml of oxygen, in the future, 100 ml are added daily, i.e. on the second day it receives 600 ml, on the third - 700 ml, the fourth - 800 ml, the fifth - 900 ml, the sixth - 1000 ml, the seventh - 1100 ml, the eighth - 1200 ml. From the eighth day to the end of the course of treatment, the patient receives 1200 ml of oxygen daily. The course lasts 10 days for mild and moderate hepatitis and 14 days for severe illness.

Витамин В^ (пангамат кадьция) назначают внутрь в виде таблеток по 0,05 г три раза в день в течение того.же времени, что и кислород (т.е. 10 дней при легком и среднетяжелом течении вирусного гепатита и 14 дней - при тяжелом течении).Vitamin B ^ (cadmium pangamate) is prescribed orally in the form of tablets of 0.05 g three times a day during the same time as oxygen (i.e. 10 days for mild and moderate viral hepatitis and 14 days for severe course).

Пример. Больной А., 35 лет, поступил в клинику на 3 день болезни, первый день/келтухи с диагнозом: вирусный гепатит, тип В (постинъекционный) , острая желтушная форма, среднетяжелое течение. При поступлении назначен постельный режим,диета (стол 5а) , 10%-ый раствор глюкозы по 200 мл 3 раза в день внутрь, аскорУбиновая кислота по 0,02 г три раза в день внутрь, поливитамины по 1 драже три раза в день. Со второго дня госпитализации назначено комплексное лечение в соответствии с предлагаемым способом: кислород внутриректально по схеме (от 500 до 1200 мл) нуклеинат натрия по 0,5 г три раза в день внутри и витамин Вц.по PjJj г три раза в день внутрь.Example. Patient A., 35 years old, was admitted to the clinic on the 3rd day of illness, the first day / keltuha with a diagnosis of viral hepatitis, type B (post-injection), acute icteric form, moderate course. Upon admission, bed rest, diet (table 5a), a 10% glucose solution of 200 ml 3 times a day inside, ascorbic acid 0.02 g three times a day inside, multivitamins 1 tablet three times a day were prescribed. From the second day of hospitalization, a complex treatment was prescribed in accordance with the proposed method: oxygen intrarectally according to the scheme (from 500 to 1200 ml) sodium nucleate 0.5 g three times a day inside and vitamin B.by PjJj g three times a day inside.

Лечение кислородом, витамином В^ и нукпеинатом натрия продолжалось 10 дней, базисная терапия осуществлялась все время пребывания в клинике.Treatment with oxygen, vitamin B ^ and sodium nuccinate lasted 10 days, basic therapy was carried out throughout the stay in the clinic.

Билирубиновый криз у больного наступил на четвертый день лечения, продолжительность желтушного периода равна 14 дням. Выписан из клиники на двадцатый день, клинически здоро₁₀ вым.The bilirubin crisis in the patient occurred on the fourth day of treatment, the duration of the icteric period is 14 days. Discharged from the clinic on the twentieth day, clinically healthy ₁₀ vym.

Предлагаемый способ способствует ускорению 'нормализации биохимических и гематологических показателей и позволяет сократить сроки лечения с ₁₅ 30 дней известным способом по 20 дней.The proposed method helps to accelerate the normalization of biochemical and hematological parameters and can reduce treatment time from _{15 to} 30 days in a known manner for 20 days.

Claims

The invention relates to medicine and to the treatment of infectious diseases, namely the treatment of viral hepatitis. There is a method of treating viral hepatitis with a diet and DJ vitamins. However, treatment with the known method is long-term. The purpose of the invention is to reduce the duration of treatment. This goal is achieved by the fact that in the method of treating viral hepatitis, carried out by diet and vitamins, rectal oxygen therapy at a dose of 500-1200 ml is simultaneously administered and sodium nucleinate is administered at a dose of 1.5-1.0 g. Patients with viral hepatitis In addition to dietary treatment, sodium nucleinate is treated with 0.5 g three times a day orally, intrarectal oxygen therapy, and vitamin (paigama cap) 0.05 g three times a day. Sodium nucleate is administered in the form of a powder 0.5 g inside three times a day after meals. With mild and moderate hepatitis, treatment is continued for 10 days (15 g of sodium nucleinate per course), with severe course the drug is prescribed for 14 days (21 g of sodium nucleinate per course). Intrarectal oxygen therapy is performed daily in the morning on an empty stomach after a cleansing enema using a thin bezolivny probe. The oxygen dosage is carried out using an artificial pneumothorax superimposition apparatus. The probe is inserted into the rectum to a depth of 10-15 cm and in the position of the patient on the left side; oxygen is introduced into the intestine. On the first day, he receives 500 ml of oxygen, then 100 ml are added daily, i.e. on the second day, it receives 600 ml, on the third - 700 ml, the fourth - 800 ml, the fifth - 900 ml, the sixth - 1000 ml, the seventh - 1100 ml. 5 eighth - 1200 MJi. From the eighth day until the end of the course of treatment, the patient receives 1200 ml of oxygen daily. The course lasts 10 days with mild and moderate hepatitis and 14 days with severe disease. Vitamin Vu ((pangamat; 1b1cc) is prescribed orally in the form of tablets of 0.05 g three times a day for the time that oxygen is (i.e. 10 days for mild to moderate viral hepatitis and 14 days for severe flow.) Example: Patient A., 35 years old, was admitted to the hospital for 3 days of illness, the first day of the elderly with a diagnosis of viral hepatitis, type B (post-injection), acute icteric form, moderate course. At proceeds, bed rest was prescribed, diet (table 5a), 10% gluco solution, 200 ml 3 times a day, orally ingested as acid, 0.02 g three times a day inside, multivitamins 1 tablet three times a day. From the second day of hospitalization, a comprehensive treatment was prescribed in accordance with the proposed method: KJ hydrochloride intra rectally PS scheme (from 500 to 1200 ml of sodium nucleinate 0.5 g three times a day inside and Vitamin B. Pj g three times a day orally. Treatment with oxygen, vitamin B, C and sodium nucleinate lasted 10 days, the basic therapy was carried out throughout the stay in the clinic. The bilirubin crisis in the patient came on the fourth day of treatment, the duration of the icteric period was 14 days. Discharged from the clinic on the twentieth day, clinically healthy. The proposed method helps to accelerate the normalization of biochemical and hematological parameters and reduces the treatment time from 30 days in a known manner to 20 days. The invention of the method of treating viral hepatitis with a diet and vitamins, is due to the fact that, in order to shorten the treatment time, intrarectal oxygen therapy is simultaneously carried out in a dose of 500-1200 ml and sodium nuleinate is administered in a dose of 1.51, 0 g. Sources of information taken into account in the examination 1. Practical doctor's guide. Ed. Kochergina I.G. and others. M., Medicine, 1975, p. 204.