SU686731A1 - Hair integument growth factor - Google Patents
Hair integument growth factorInfo
- Publication number
- SU686731A1 SU686731A1 SU731954519A SU1954519A SU686731A1 SU 686731 A1 SU686731 A1 SU 686731A1 SU 731954519 A SU731954519 A SU 731954519A SU 1954519 A SU1954519 A SU 1954519A SU 686731 A1 SU686731 A1 SU 686731A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- hair
- growth factor
- wool
- growth
- hair integument
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Description
II
Изобретение относитс к медицине, касаетс стимул тора роста волос ного покрова и может найти применение в косметологии , ветер1шарии.The invention relates to medicine, concerns a stimulator of hair growth and can be used in cosmetology, wind.
Известно вещество 1-замеще1шых силатрана формулы X - Si ()в которых х-углеводородный заместитель, функциональна или карбофункциональна группа, в качестве химического соединени 1.A 1-substituted silatrane substance of the formula X - Si () is known in which the x-hydrocarbon substituent, functional or carboxylic acid group, as chemical compound 1.
Целью изобретени вл етс ускорение роста волос ного покрова.The aim of the invention is to accelerate the growth of hair.
Это достигаетс применением 1-замещенных силатрана общей ффмулы X-Si (OCH2CH2)jN , где х-углеводород- ный заместитель, функциональна и кар- б.офункциональна группа, в качестве стимул тора роста волос ного по1фова.This is achieved by using 1-substituted silatrane X-Si total formula (OCH2CH2) jN, where the x-hydrocarbon substituent, functional and car- bly functional group, as a hair growth stimulator.
Эти производные не токсичны otDg 1500 мг/кг. Они не обладают раздражающим или каким-либо другим побочным действием. Исследовани проводились на 9О здоровых морских свинках с нормальным шерстным покровом.These derivatives are non-toxic otDg 1500 mg / kg. They do not have irritating or any other side effects. Studies were performed on 9O healthy guinea pigs with normal coat.
У животных состригают волосы с площади 1 см в области спины. Выстриженные волосы промьгаают эфиром (дл удалени гр зи), сушат и определ ют их вес (дл характеристики густоты покрова волос животных). Затем берут 1/4 часть выстриженных волос (по весу) и подсчитьтают количество отдельных волосков. Зна их вес и число, определ ют количество волосков во вз том образце. Кроме того, определ ют длину и толщину волос .In animals, hair is cut from an area of 1 cm in the back area. Shorn hair is washed with ether (to remove dirt), dried and their weight is determined (to characterize the thickness of the animal hair). Then take 1/4 of the clipped hair (by weight) and calculate the number of individual hairs. Knowing their weight and number, determine the number of hairs in the sample taken. In addition, the length and thickness of the hair is determined.
После вз ти фона животным дают 5 раз в неделю вместе с пищей силатран в дозе 1О и 50 мг в день в течение 2 мес. Прирост шерсти более значителен в опытной группе, чем в контроле. При использовании Х-метил-силатран а в дозе 1О мг прирост шерсти составил 35%, а при дозе .50 мг- 40,5%.After taking the background, animals are given 5 times a week with food silatran at a dose of 1O and 50 mg per day for 2 months. Wool growth is more significant in the experimental group than in the control. When using X-methyl-silatran a at a dose of 10 mg, the increase in wool was 35%, and at a dose of 50 mg it was 40.5%.
При лечении маз ми, содержащими 5 и 10% 1-этокси-силатрана(мигугена) 1-этилсилатрана и 1-хлор метил-силатрана (мивала) лучший результат наблюдалс When treating ointments containing 5 and 10% 1-ethoxy-silatrane (migugen) 1-ethylsilane and 1-chloro methyl-silatrane (mival), the best result was observed
при применении 5% мази 1-этоксисилатрана . Прирост шерсти составил 55,4%, а 10% мази - 41,4%.when using 5% ointment 1-ethoxysilatran. The growth of wool was 55.4%, and 10% ointment - 41.4%.
При использовании мази, содержащей 5% 1-хлор метил-силатрана шерсть у жи-вотных отрастает в 1,5 раза быстрее. Прирост шерсти составил ЗО%.When using an ointment containing 5% 1-chloro methyl-silatran, wool in animals grows 1.5 times faster. The increase in wool was ZO%.
Проведенные исследовани с использованием силатранов в виде мазей показали , что наибольшим стимулирующим действием на рост шерсти обладает 1-этоксисилатран , 1-метилсилатран и 1-хлорметилсилатран .Studies conducted with the use of silatranes in the form of ointments showed that 1-ethoxysilatrane, 1-methylsilatrane and 1-chloromethylsilatran has the greatest stimulating effect on the growth of wool.
Предлагаемые стимул торы роста волос ного покрова могут найти широкое применение в овцеводческих совхозах и зверосовхозах , а также в клинической практике дл лечени различных видов облысени у людей.The proposed hair growth stimulants can be widely used in sheep state farms and animal farms, as well as in clinical practice for the treatment of various types of baldness in humans.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU731954519A SU686731A1 (en) | 1973-07-26 | 1973-07-26 | Hair integument growth factor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU731954519A SU686731A1 (en) | 1973-07-26 | 1973-07-26 | Hair integument growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU686731A1 true SU686731A1 (en) | 1979-09-25 |
Family
ID=20563126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU731954519A SU686731A1 (en) | 1973-07-26 | 1973-07-26 | Hair integument growth factor |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU686731A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19534201A1 (en) * | 1995-09-15 | 1997-03-20 | Lohmann Therapie Syst Lts | Preparation for the prophylaxis and / or treatment of wool and hair loss |
-
1973
- 1973-07-26 SU SU731954519A patent/SU686731A1/en active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19534201A1 (en) * | 1995-09-15 | 1997-03-20 | Lohmann Therapie Syst Lts | Preparation for the prophylaxis and / or treatment of wool and hair loss |
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