SU529153A1 - The method of obtaining saturated amino acids - Google Patents
The method of obtaining saturated amino acidsInfo
- Publication number
- SU529153A1 SU529153A1 SU2140371A SU2140371A SU529153A1 SU 529153 A1 SU529153 A1 SU 529153A1 SU 2140371 A SU2140371 A SU 2140371A SU 2140371 A SU2140371 A SU 2140371A SU 529153 A1 SU529153 A1 SU 529153A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- amino acids
- saturated amino
- obtaining saturated
- mol
- water
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
8eight
стапл юшуЙ собой кои 1ентрированиый водный раствор галанина. Полученную аминокислоту BbiaofiflioT путем иерекристалли.эации. После ухлзашшй обработки получают 87.2 г J -ала (шн (т. пл, 195-1960С) с выходом 98% , от теоретического в расчете на вз тый акрилон трйл .Staples Yushi Koi 1centric aqueous solution of galanin. The resulting amino acid BbiaofiflioT by heterocrystal.eation. After a thorough treatment, 87.2 g of J-al (Sn (mp, 195-1960 ° C)) is obtained with a yield of 98%, from the theoretical calculated on the acrylon triple taken.
Пример 2. В автоклав загружают 45 г воды (2,5 моль), 53 г (1,0 моль) акрилон1 трила и 10,2 г (10 вес.% от обшего веса смеси акрилонитрил + вода) гидроокиси бари . Смесь нагревают при температуре в течение 1 час и парциаль. ном давлении 3 атм. После обработки вьщеп ют 85,4 г -вланина с выходом 96% от теог етичёского в расчете на вз тый акрилонигрил .Example 2. 45 g of water (2.5 mol), 53 g (1.0 mol) of acrylon1 tril and 10.2 g (10 wt.% Of the total weight of acrylonitrile + water) of barium hydroxide are charged to an autoclave. The mixture is heated at a temperature for 1 hour and a partial. nom pressure of 3 atm. After treatment, 85.4 g of Vlanin is recovered with a yield of 96% of the theogetic, based on the acrylonigryl taken.
Пример 3. В автоклав загружают 45 г (2,5 моль) воды, 67 г (1,0моль) метакрилонитрила, 5,6 г (5 вес.% от общего веса смеси етакрилонйтрилЛ вода) безводного едкого кали. Смесь нагревают при температуре 120-130°С в течение 1,0 час и парциальном давлении 4-5 атм. После обработки выдел кУГ 100,9 г ti-метил-Р-аланина (т.пл. 171-172 С с выходом 98% от теоретического в расчете на вз тый мета филонитрш1 ,Example 3. 45 g (2.5 mol) of water, 67 g (1.0 mol) of methacrylonitrile, 5.6 g (5 wt.% Of the total weight of the mixture of ethyl chloride) of anhydrous potassium hydroxide are loaded into an autoclave. The mixture is heated at a temperature of 120-130 ° C for 1.0 hour and a partial pressure of 4-5 atm. After the treatment, the separation of a CUG of 100.9 g of ti-methyl-P-alanine (mp. 171-172 ° C in 98% of the theoretical, calculated on the basis of the taken meta phonon1,
П р и м е р 4. В автоклав загружают 45 г (2i5 моль)воды , 67 г (1,О моль) PRI me R 4. In the autoclave load 45 g (2i5 mol) of water, 67 g (1, O mol)
|метакрилошп:рила, 11,5 г (10 вес,% от о шего веса смеси. метакрилонитрил + вода) riiflpooKHCH бари . Смесь нагревают при температуре 120-1ЙО°С в течение 1 час при па1щиальном давлении 4-5 атм. После обработки выдел ют 98,9 г с1-метил-В-аланина с выходом теоретического в расчете на вз тый метакрилонитрил.| methacrylosp: ril, 11.5 g (10 wt.% of the total weight of the mixture. methacrylonitrile + water) riiflpooKHCH bari. The mixture is heated at a temperature of 120-1 ° C for 1 hour at a massive pressure of 4-5 atm. After the treatment, 98.9 g of C1-methyl-B-alanine are isolated with a yield of theoretical per methacrylonitrile taken.
изобретени the invention
Способ получени насыщенных аминокислот из dU3-ненасыщенных нитрилов с применением реакции гидролиза, отличающийс тем, что, с целью упрошени процесса и увеличени выхода целевого продукта , dL, JB -ненасьшенный нитрил обрабатывают водой при температуре 40-160 С и давлении 2-10 атм в присутствии гидроокиси шелочных или шелочноземельных металлов .The method of obtaining saturated amino acids from dU3-unsaturated nitriles using the hydrolysis reaction, characterized in that, in order to simplify the process and increase the yield of the target product, dL, JB -nitrated nitrile is treated with water at a temperature of 40-160 ° C and a pressure of 2-10 atm. the presence of hydroxide of silk or silk earth metals.
1. Авт. СБ. СССР № 455945, М. Кл. С О7 с 101/08, 05.01.75. 2,. Патент США № 3846489, Класс 26О-534у05Д1 .74.1. Auth. Sat USSR № 455945, M. Kl. From O7 from 101/08, 05.01.75. 2 ,. U.S. Patent No. 3846489, Class 26O-534th05D1 .74.
5.PoppeC dopf ,Ьеп1Ол U-C-.a-mproved syntheses oi p-aeanine, J-Or-g-.CtieTn.Zd.iez, Jl961r.5.PoppeC dopf, Lip1Ol U-C-.a-mproved syntheses oi p-aeanine, J-Or-g-.CtieTn.Zd.iez, Jl961r.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU2140371A SU529153A1 (en) | 1975-06-03 | 1975-06-03 | The method of obtaining saturated amino acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU2140371A SU529153A1 (en) | 1975-06-03 | 1975-06-03 | The method of obtaining saturated amino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU529153A1 true SU529153A1 (en) | 1976-09-25 |
Family
ID=20621420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU2140371A SU529153A1 (en) | 1975-06-03 | 1975-06-03 | The method of obtaining saturated amino acids |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU529153A1 (en) |
-
1975
- 1975-06-03 SU SU2140371A patent/SU529153A1/en active
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