SU522795A3 - The method of obtaining 1-phenoxy-2oxy-3-aminopropane or its salts - Google Patents
The method of obtaining 1-phenoxy-2oxy-3-aminopropane or its saltsInfo
- Publication number
- SU522795A3 SU522795A3 SU2078419A SU2078419A SU522795A3 SU 522795 A3 SU522795 A3 SU 522795A3 SU 2078419 A SU2078419 A SU 2078419A SU 2078419 A SU2078419 A SU 2078419A SU 522795 A3 SU522795 A3 SU 522795A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- salts
- aminopropane
- obtaining
- 2oxy
- phenoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Description
1one
Изобретение относитс к способу получени новых производных аминопропана, которые обладают фармакологической активностью и могут найти применение в медицине.This invention relates to a process for the preparation of new aminopropane derivatives, which have pharmacological activity and can be used in medicine.
Известны различные производные аминоспиртов , обладающие -адренергической блокирующей активностью.There are various derivatives of amino alcohols, possessing β-adrenergic blocking activity.
Известен способ получени аминоспиртов обшей формулыA known method of producing amino alcohols of the general formula
ОНHE
1/СНз1 / SNZ
0-СН-СН-СН,гМН-СН 0-CH-CH-CH, GMN-CH
/ СНз / SNZ
по которому соединение формулыin which the compound of the formula
У X I I о-сн2-сн-снAt X I I o-sn2-th-th
O-CHg -СН СН2O-CHg -CH CH2
где X - гидроксил,where X is hydroxyl,
У - сложноэфирна группировка или X и У вместе - эпоксидна группа,Y - ester group or X and Y together - epoxy group,
подвергают взаимодействию с изопропиламином в среде инертного растворител , например спирта.subjected to interaction with isopropylamine in an inert solvent, for example alcohol.
Однако в литературе отсутствуют сведени о способе получени аминов общей формулыHowever, in the literature there is no information about the method of obtaining amines of the general formula
a. dk- А,a. dk- A,
где А - группа формулыwhere A is a group of the formula
ОН IOH I
-CH-CK -NH-R-CH-CK -NH-R
илиor
1515
-CHi-CHi
-СН Q- CH Q
N-Я,NI,
Х/X /
где ufk - низший алкил ,,where ufk is lower alkyl ,,
afb2 -этилен-1,2 или пронилен-1,3;afb2-ethylene-1,2 or pronyl-1,3;
R - низший алкил ; Х-метилен , изопропилен- С (СНз)2 карбонил, или его солей, которые обладают ценными свойсгвами.R is lower alkyl; X-methylene, isopropyl-C (CH3) 2 carbonyl, or its salts, which possess valuable properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH62173A CH576438A5 (en) | 1973-01-17 | 1973-01-17 | 1-Alkylthioalkoxy-4-(3-amino-2-hydroxypropoxy) benzenes - antagonists of beta receptor stimulants prepd. e.g. by reducing corresp. Schiff base |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU522795A3 true SU522795A3 (en) | 1976-07-25 |
Family
ID=4191269
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU2078419A SU522795A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining 1-phenoxy-2oxy-3-aminopropane or its salts |
| SU2078416A SU558638A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining compounds of 1-phenoxy-2-hydroxy-3-aminopropane or their salts in the form of a racemate or an optically active antipode |
| SU2078418A SU518125A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining 1-phenoxy-2-hydroxy-3-aminopropane or its salts |
| SU2078415A SU522794A3 (en) | 1973-01-17 | 1974-11-26 | Method for producing -1-phenoxy-2-hydroxy-3-aminopropane derivatives or their salts |
| SU2078417A SU518124A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining 1-phenoxy-2-hydroxy-aminopropane or its salts |
| SU7502168216A SU576916A3 (en) | 1973-01-17 | 1975-09-04 | Method of preparing derivatives of 1-phenoxy-2-oxy-3-aminopropane,their salts,racemates or optically active antipodes |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU2078416A SU558638A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining compounds of 1-phenoxy-2-hydroxy-3-aminopropane or their salts in the form of a racemate or an optically active antipode |
| SU2078418A SU518125A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining 1-phenoxy-2-hydroxy-3-aminopropane or its salts |
| SU2078415A SU522794A3 (en) | 1973-01-17 | 1974-11-26 | Method for producing -1-phenoxy-2-hydroxy-3-aminopropane derivatives or their salts |
| SU2078417A SU518124A3 (en) | 1973-01-17 | 1974-11-26 | The method of obtaining 1-phenoxy-2-hydroxy-aminopropane or its salts |
| SU7502168216A SU576916A3 (en) | 1973-01-17 | 1975-09-04 | Method of preparing derivatives of 1-phenoxy-2-oxy-3-aminopropane,their salts,racemates or optically active antipodes |
Country Status (7)
| Country | Link |
|---|---|
| AT (3) | AT329538B (en) |
| CH (1) | CH576438A5 (en) |
| CS (6) | CS184345B2 (en) |
| MC (1) | MC1010A1 (en) |
| PL (6) | PL98065B1 (en) |
| SU (6) | SU522795A3 (en) |
| ZA (1) | ZA74307B (en) |
-
1973
- 1973-01-17 CH CH62173A patent/CH576438A5/en not_active IP Right Cessation
-
1974
- 1974-01-11 CS CS7700000290A patent/CS184345B2/en unknown
- 1974-01-11 CS CS7700000294A patent/CS184349B2/en unknown
- 1974-01-11 CS CS7700000289A patent/CS184344B2/en unknown
- 1974-01-11 CS CS7700000291A patent/CS184346B2/en unknown
- 1974-01-11 CS CS7400000191A patent/CS184336B2/en unknown
- 1974-01-11 CS CS7700000293A patent/CS184348B2/en unknown
- 1974-01-16 PL PL1974183006A patent/PL98065B1/en unknown
- 1974-01-16 PL PL1974183004A patent/PL98966B1/en unknown
- 1974-01-16 PL PL1974183005A patent/PL97727B1/en unknown
- 1974-01-16 PL PL1974168144A patent/PL99161B1/en unknown
- 1974-01-16 AT AT34674*#A patent/AT329538B/en not_active IP Right Cessation
- 1974-01-16 PL PL1974185368A patent/PL98965B1/en unknown
- 1974-01-16 AT AT397775A patent/AT331241B/en not_active IP Right Cessation
- 1974-01-16 ZA ZA740307A patent/ZA74307B/en unknown
- 1974-01-16 PL PL1974183007A patent/PL98225B1/en unknown
- 1974-01-17 MC MC1083A patent/MC1010A1/en unknown
- 1974-11-26 SU SU2078419A patent/SU522795A3/en active
- 1974-11-26 SU SU2078416A patent/SU558638A3/en active
- 1974-11-26 SU SU2078418A patent/SU518125A3/en active
- 1974-11-26 SU SU2078415A patent/SU522794A3/en active
- 1974-11-26 SU SU2078417A patent/SU518124A3/en active
-
1975
- 1975-05-23 AT AT393675A patent/AT331793B/en not_active IP Right Cessation
- 1975-09-04 SU SU7502168216A patent/SU576916A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AT331793B (en) | 1976-08-25 |
| SU558638A3 (en) | 1977-05-15 |
| CS184336B2 (en) | 1978-08-31 |
| CS184345B2 (en) | 1978-08-31 |
| PL97727B1 (en) | 1978-03-30 |
| ATA397775A (en) | 1975-11-15 |
| AT329538B (en) | 1976-05-10 |
| CS184348B2 (en) | 1978-08-31 |
| PL98966B1 (en) | 1978-06-30 |
| ATA34674A (en) | 1975-08-15 |
| SU576916A3 (en) | 1977-10-15 |
| SU518124A3 (en) | 1976-06-15 |
| CH576438A5 (en) | 1976-06-15 |
| SU522794A3 (en) | 1976-07-25 |
| CS184349B2 (en) | 1978-08-31 |
| SU518125A3 (en) | 1976-06-15 |
| PL98965B1 (en) | 1978-06-30 |
| PL98065B1 (en) | 1978-04-29 |
| PL98225B1 (en) | 1978-04-29 |
| AT331241B (en) | 1976-08-10 |
| ZA74307B (en) | 1974-11-27 |
| PL99161B1 (en) | 1978-06-30 |
| MC1010A1 (en) | 1974-10-18 |
| CS184344B2 (en) | 1978-08-31 |
| CS184346B2 (en) | 1978-08-31 |
| ATA393675A (en) | 1975-12-15 |
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