SU502875A1 - Method for preparing 4-dimethylaminosalicylic acid methyl ester - Google Patents

Method for preparing 4-dimethylaminosalicylic acid methyl ester

Info

Publication number
SU502875A1
SU502875A1 SU1900129A SU1900129A SU502875A1 SU 502875 A1 SU502875 A1 SU 502875A1 SU 1900129 A SU1900129 A SU 1900129A SU 1900129 A SU1900129 A SU 1900129A SU 502875 A1 SU502875 A1 SU 502875A1
Authority
SU
USSR - Soviet Union
Prior art keywords
methyl ester
acid methyl
preparing
dimethylaminosalicylic acid
dimethylaminosalicylic
Prior art date
Application number
SU1900129A
Other languages
Russian (ru)
Inventor
Овшей Мошкович Лернер
Тамара Михайловна Тимофеева
Original Assignee
Войсковая Часть 41598
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Войсковая Часть 41598 filed Critical Войсковая Часть 41598
Priority to SU1900129A priority Critical patent/SU502875A1/en
Application granted granted Critical
Publication of SU502875A1 publication Critical patent/SU502875A1/en

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Description

конце в вакууме водоструйного насоса). Остаток после обработки водой закристаллизовываетс  в виде гранул, которые отфильтровывают , промывают водой, 5-10%-ной уксусной кислотой, затем снова водой. После кристаллизации из водной уксусной кислоты получают 9,75-10,7 г (50-55%) очищенного эфира 4-диметиламиносалициловой кислоты с т. пл. 85-86°С.end of a water jet pump vacuum). The residue after treatment with water is crystallized in the form of granules, which are filtered, washed with water, 5-10% acetic acid, then again with water. After crystallization from aqueous acetic acid, 9.75-10.7 g (50-55%) of purified 4-dimethylaminosalicylic acid ester are obtained with a mp. 85-86 ° C.

Литературные данные т. пл. 85-88, 86- 87°С.Literary data so pl. 85-88, 86-87 ° C.

Claims (1)

Формула изобретени Invention Formula Способ получени  метилового эфира 4-диметиламиносалициловой кислоты с применением реакции алкилировани  диметилсульфатом в присутствии бикарбоната натри , отличающийс  тем, что, с целью упрощени  процесса , алкилированию подвергают 4-аминосалициловую кислоту и процесс провод т в среде органического растворител , такого как ацетон.A method of producing 4-dimethylaminosalicylic acid methyl ester using an alkylation reaction with dimethyl sulfate in the presence of sodium bicarbonate, characterized in that, in order to simplify the process, 4-aminosalicylic acid is alkylated and the process is carried out in an organic solvent such as acetone.
SU1900129A 1973-03-26 1973-03-26 Method for preparing 4-dimethylaminosalicylic acid methyl ester SU502875A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU1900129A SU502875A1 (en) 1973-03-26 1973-03-26 Method for preparing 4-dimethylaminosalicylic acid methyl ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU1900129A SU502875A1 (en) 1973-03-26 1973-03-26 Method for preparing 4-dimethylaminosalicylic acid methyl ester

Publications (1)

Publication Number Publication Date
SU502875A1 true SU502875A1 (en) 1976-02-15

Family

ID=20547357

Family Applications (1)

Application Number Title Priority Date Filing Date
SU1900129A SU502875A1 (en) 1973-03-26 1973-03-26 Method for preparing 4-dimethylaminosalicylic acid methyl ester

Country Status (1)

Country Link
SU (1) SU502875A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100269079B1 (en) * 1995-05-23 2000-10-16 안토니오 칸탈루피 Process for the preparation of a halosubstituted aromatic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100269079B1 (en) * 1995-05-23 2000-10-16 안토니오 칸탈루피 Process for the preparation of a halosubstituted aromatic acid

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