SU417139A1 - - Google Patents
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- Publication number
- SU417139A1 SU417139A1 SU1824138A SU1824138A SU417139A1 SU 417139 A1 SU417139 A1 SU 417139A1 SU 1824138 A SU1824138 A SU 1824138A SU 1824138 A SU1824138 A SU 1824138A SU 417139 A1 SU417139 A1 SU 417139A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- erythromycin
- oil
- drugs
- antibiotics
- drug
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
1one
Изобретение относитс к ветеринарным нрепаратам дл лечени маститов животных, например крупного рогатого скота.This invention relates to veterinary drugs for treating mastitis of animals, for example cattle.
Известные препараты, представл ющие собой смесь антибиотиков и сульфамидных препаратов На масл ной основе, обладают недостаточным терапевтическим эффектом ири введении влутрь вымени, прежде всего за счет быстрого рассасывани и выведени препарата с молоком при лактации.Known drugs that are a mixture of antibiotics and sulfa drugs. On an oil basis, they have insufficient therapeutic effect when administered to the udder, primarily due to the rapid resorption and removal of the drug with milk during lactation.
В предлагаемом препарате в качестве масл ной основы в состав введена полиэтилсилоксанова жидкость, способствующа длительному удержанию активных веществ в цистерне вымени, что позвол ет существенно снизить кратность введени препарата в нро цессе лечени .In the proposed preparation, polyethylsiloxane fluid is introduced into the composition as an oil base, which contributes to the long-term retention of the active substances in the udder tank, which significantly reduces the number of times the drug is administered during the treatment process.
В качестве масл ной основы могут быть использова .ны различные силиконовые масла. Экспериментальной проверкой установлено, что терапевтический эффект наблюдаетс приVarious silicone oils can be used as the oil base. Experimentally verified that the therapeutic effect is observed when
22
применении смеси эритромицина (300- 500 тыс. М. Е.) и сульфадимезина (0,35- 0,70 г), эмульгированных в 5 г силиконового масла.the use of a mixture of erythromycin (300-500 thousand IU. E.) and sulfadimezina (0.35-0.70 g), emulsified in 5 g of silicone oil.
Наиболее оптимальным соотношением вл етс 0,1 г эритромицина и 0,4 г сульфадимезина на 5 г силиконового масла Эсилоп 5. При таком соотношении компонентов концентраци антибиотиков в молоке поддерживаетс в иределах О-8-1,0 Л1. Е./мл в течение 4-5 СУТОК после введени атрепарата.The most optimal ratio is 0.1 g of erythromycin and 0.4 g of sulfadimezine per 5 g of Esilop 5 silicone oil. With this ratio of components, the concentration of antibiotics in milk is maintained at a level of O-8-1.0 L1. E. / ml for 4-5 days after the introduction of atreparata.
Пред М е т изобретени Prev Invention
Препарат дл лечени маститов животных, содержащий активные вещества, например эритром.ицин и сульфадимезин, масл ную основу и эмульгатор, отличающийс тем, что, с целью увеличени срока действи активных веществ, в качестве масл ной основы примен ют полиэтилсилоксановую жидкость, например силиконове масло Эсилон 5.A preparation for treating animal mastitis containing active substances, e.g. erythromycin and sulfadimesin, an oily base and an emulsifier, characterized in that, in order to increase the active substance's duration, a polyethylene siloxane liquid is used, e.g. five.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU1824138A SU417139A1 (en) | 1972-08-21 | 1972-08-21 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU1824138A SU417139A1 (en) | 1972-08-21 | 1972-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
SU417139A1 true SU417139A1 (en) | 1974-02-28 |
Family
ID=20525827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU1824138A SU417139A1 (en) | 1972-08-21 | 1972-08-21 |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU417139A1 (en) |
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1972
- 1972-08-21 SU SU1824138A patent/SU417139A1/ru active
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