SU289590A1 - - Google Patents
Info
- Publication number
- SU289590A1 SU289590A1 SU1207929A SU1207929A SU289590A1 SU 289590 A1 SU289590 A1 SU 289590A1 SU 1207929 A SU1207929 A SU 1207929A SU 1207929 A SU1207929 A SU 1207929A SU 289590 A1 SU289590 A1 SU 289590A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- salts
- benzenesulfonylurea
- formula
- alkali
- benzolsulfomochevin
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000003513 alkali Substances 0.000 description 2
- GHDLZGOOOLEJKI-UHFFFAOYSA-N benzenesulfonylurea Chemical compound NC(=O)NS(=O)(=O)C1=CC=CC=C1 GHDLZGOOOLEJKI-UHFFFAOYSA-N 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 125000004432 carbon atoms Chemical group C* 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 230000000875 corresponding Effects 0.000 description 1
- -1 ethoxymethoxy Chemical group 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical group 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atoms Chemical class [H]* 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 description 1
- 238000005020 pharmaceutical industry Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
Description
СПОСОБ ПОЛУЧЕНИЯ БЕНЗОЛСУЛЬФОМОЧЕВИНMETHOD OF OBTAINING BENZOLSULFOMOCHEVIN
где Z и X имеют вышеуказанное значение, подвергают взаимодействию с сол ми тропили с последующим гидрированием образующейс при этом бензолсульфоциклогептатриенилмочевины и выделением целевого дродукта известным способом.where Z and X have the above meaning, they are reacted with tropyl salts, followed by hydrogenation of the benzenesulfocycloheptatrienylurea formed and the isolation of the target product in a known manner.
присутствии средств, св зывающих кислоту, таких как щелочные карбонаты и щелочные бикарбонаты. Следует также примен емую в качестве исходной бензолсульфонилмочевину вводить в виде соответствующих солей.in the presence of acid binding agents such as alkali carbonates and alkali bicarbonates. It should also be used as the starting benzenesulfonylurea in the form of the corresponding salts.
1 Изобретение относитс к способу получени щей формулы1 The invention relates to a process for the preparation of the formula
О с о-NH-CH -CHf Q -ЗОг-N Н-со-NH-VZO или их солей, -где Z - водород, алкокси с 1- 4 атомами углерода, аллнлокси, метоксимет-10 окси, этоксиметокси; X - галоид, преимущественно хлор, метил, трифторметил, метокси «ли, если Z - ал.кокси или алкенокси, ,во .O with o-NH-CH-CHf Q-Og-N H-co-NH-VZO or their salts, -here Z is hydrogen, alkoxy with 1-4 carbon atoms, allnloxy, methoxymetho-10 oxy, ethoxymethoxy; X is halogen, preferably chlorine, methyl, trifluoromethyl, methoxy, if Z is al.coxy or alkenoxy,, in.
-CO-NH-CHa-CHz-Q SOj-NK-CO-NHj 2 неизвестных ранее бензолсульфомочевин обдород , которые могут найти применение в фармацевтической промышленности. Способ состоит в том, что бензолсульфомочевину общей формулы-CO-NH-CHa-CHz-Q SOj-NK-CO-NHj 2 previously unknown benzenesulfonylurea fenestrate, which can be used in the pharmaceutical industry. The method consists in the fact that benzenesulfonamine General formula
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1403610A SU363245A3 (en) | 1967-01-03 | 1968-01-02 | |
| SU1403555A SU372808A3 (en) | 1967-01-03 | 1968-01-02 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0051164 | 1967-01-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SU289590A1 true SU289590A1 (en) | |
| SU366605A3 SU366605A3 (en) | 1973-01-16 |
Family
ID=7104389
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1623403A SU448641A3 (en) | 1967-01-03 | 1968-01-02 | Method for preparing benzenesulfonylurea |
| SU1207929A SU366605A3 (en) | 1967-01-03 | 1968-01-02 | |
| SU1406180A SU468402A3 (en) | 1967-01-03 | 1968-01-02 | Method for preparing substituted benzenesulfonylurea |
| SU1406183A SU453829A3 (en) | 1967-01-03 | 1968-01-02 | METHOD FOR OBTAINING SUBSTITUTED BENZENE SULPHONYLMOLOVIE |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1623403A SU448641A3 (en) | 1967-01-03 | 1968-01-02 | Method for preparing benzenesulfonylurea |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1406180A SU468402A3 (en) | 1967-01-03 | 1968-01-02 | Method for preparing substituted benzenesulfonylurea |
| SU1406183A SU453829A3 (en) | 1967-01-03 | 1968-01-02 | METHOD FOR OBTAINING SUBSTITUTED BENZENE SULPHONYLMOLOVIE |
Country Status (21)
| Country | Link |
|---|---|
| AT (1) | AT327935B (en) |
| BE (1) | BE708917A (en) |
| CH (7) | CH566974A5 (en) |
| CS (1) | CS161702B2 (en) |
| CY (1) | CY586A (en) |
| DE (1) | DE1618333C3 (en) |
| DK (2) | DK123865B (en) |
| ES (2) | ES348773A1 (en) |
| FI (1) | FI49157C (en) |
| FR (2) | FR1559029A (en) |
| GB (1) | GB1205322A (en) |
| IL (1) | IL29182A (en) |
| IS (1) | IS897B6 (en) |
| LU (1) | LU55140A1 (en) |
| MC (1) | MC698A1 (en) |
| MY (1) | MY7100110A (en) |
| NL (1) | NL6717808A (en) |
| NO (1) | NO123385B (en) |
| OA (1) | OA03383A (en) |
| SE (1) | SE339222B (en) |
| SU (4) | SU448641A3 (en) |
-
1967
- 1967-01-03 DE DE1618333A patent/DE1618333C3/en not_active Expired
- 1967-12-14 DK DK627167AA patent/DK123865B/en unknown
- 1967-12-18 IS IS1711A patent/IS897B6/en unknown
- 1967-12-20 MC MC740A patent/MC698A1/en unknown
- 1967-12-20 LU LU55140D patent/LU55140A1/xx unknown
- 1967-12-21 IL IL29182A patent/IL29182A/en unknown
- 1967-12-22 CH CH548370A patent/CH566974A5/xx not_active IP Right Cessation
- 1967-12-22 CH CH548570A patent/CH566975A5/xx not_active IP Right Cessation
- 1967-12-22 CH CH548470A patent/CH567464A5/xx not_active IP Right Cessation
- 1967-12-22 CH CH548270A patent/CH566973A5/xx not_active IP Right Cessation
- 1967-12-22 CH CH1805167A patent/CH524579A/en not_active IP Right Cessation
- 1967-12-28 NO NO171182A patent/NO123385B/no unknown
- 1967-12-28 OA OA53137A patent/OA03383A/en unknown
- 1967-12-29 ES ES348773A patent/ES348773A1/en not_active Expired
- 1967-12-29 NL NL6717808A patent/NL6717808A/xx unknown
- 1967-12-30 FI FI673527A patent/FI49157C/en active
-
1968
- 1968-01-02 FR FR1559029D patent/FR1559029A/fr not_active Expired
- 1968-01-02 AT AT968*BA patent/AT327935B/en not_active IP Right Cessation
- 1968-01-02 SU SU1623403A patent/SU448641A3/en active
- 1968-01-02 SU SU1207929A patent/SU366605A3/ru active
- 1968-01-02 SU SU1406180A patent/SU468402A3/en active
- 1968-01-02 SU SU1406183A patent/SU453829A3/en active
- 1968-01-02 CS CS30*YA patent/CS161702B2/cs unknown
- 1968-01-03 GB GB447/68A patent/GB1205322A/en not_active Expired
- 1968-01-03 SE SE00039/68A patent/SE339222B/xx unknown
- 1968-01-03 BE BE708917D patent/BE708917A/xx unknown
- 1968-03-29 FR FR146589A patent/FR8386M/fr not_active Expired
-
1969
- 1969-04-29 ES ES366601A patent/ES366601A1/en not_active Expired
- 1969-05-21 DK DK275669AA patent/DK122722B/en unknown
-
1971
- 1971-04-22 CY CY58671A patent/CY586A/en unknown
- 1971-12-30 MY MY110/71A patent/MY7100110A/en unknown
-
1974
- 1974-03-22 CH CH1805167A patent/CH593249A5/xx not_active IP Right Cessation
- 1974-12-22 CH CH554174A patent/CH592614A5/xx not_active IP Right Cessation
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