SU197567A1 - METHOD OF OBTAINING y- [p- - Google Patents
METHOD OF OBTAINING y- [p-Info
- Publication number
- SU197567A1 SU197567A1 SU1056364A SU1056364A SU197567A1 SU 197567 A1 SU197567 A1 SU 197567A1 SU 1056364 A SU1056364 A SU 1056364A SU 1056364 A SU1056364 A SU 1056364A SU 197567 A1 SU197567 A1 SU 197567A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- ethyl
- carried out
- phenyl
- triethylamine
- pyridine
- Prior art date
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 6
- ZMANZCXQSJIPKH-UHFFFAOYSA-N triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 claims description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 4
- QKFJKGMPGYROCL-UHFFFAOYSA-N Phenyl isothiocyanate Chemical class S=C=NC1=CC=CC=C1 QKFJKGMPGYROCL-UHFFFAOYSA-N 0.000 claims description 3
- NRGGMCIBEHEAIL-UHFFFAOYSA-N 2-ethylpyridine Chemical compound CCC1=CC=CC=N1 NRGGMCIBEHEAIL-UHFFFAOYSA-N 0.000 claims description 2
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 230000003197 catalytic Effects 0.000 claims description 2
- 229910052736 halogen Inorganic materials 0.000 claims description 2
- 150000002367 halogens Chemical class 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000012467 final product Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- QVLOIXWUYTWNBM-UHFFFAOYSA-N C(C)C1=NC=CC=C1.NC1=CC=CC=C1 Chemical compound C(C)C1=NC=CC=C1.NC1=CC=CC=C1 QVLOIXWUYTWNBM-UHFFFAOYSA-N 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000000855 fungicidal Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940117953 phenylisothiocyanate Drugs 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
Description
Изобретение относитс к области получени не описанных ранее (2-пиридил)этил -К-фенил-Ы -фенилтиомочевинобщейThe invention relates to the field of production of (2-pyridyl) ethyl-K-phenyl-S-phenylthiourea, not previously described.
формулыformulas
1one
RR
-CHgCH N -C-NHгде R и R-П, алкил, галоид, взаимодействием (N-фeнилaминa)этил -пиpидинa с замещенными или незамещенными фенилизотиоцианатами в присутствии каталитических количеств триэтиламина с выделением продуктов реакции известным методом.-CHgCH N -C-NH where R and R-P, alkyl, halogen, by the interaction of (N-phenylamine) ethyl-pyridine with substituted or unsubstituted phenyl isothiocyanates in the presence of catalytic amounts of triethylamine with the release of reaction products by a known method.
Реакцию можно вести в обычных органических растворител х (бензол, толуол и другие ), а также без них.The reaction can be conducted in conventional organic solvents (benzene, toluene and others), and also without them.
Полученные соединени могут найти применение в качестве фунгицидов.The resulting compounds can be used as fungicides.
хлорфепиламино)этил -п11рпдина и 0,4 г триэтилампна нагревают при 90-100°С в течение 5-7 час. Реакционную массу охлаждают, обрабатывают 200 мл этанола и отдел ют нерастворившийс продукт. Выход конечного продукта 76,8о/о; т. пл. 94-95°С.chlorfepylamino) ethyl -p11rpdine and 0.4 g of the triethylamine is heated at 90-100 ° C for 5-7 hours. The reaction mixture is cooled, treated with 200 ml of ethanol and the insoluble product is separated. The yield of the final product 76,8o / o; m.p. 94-95 ° C.
Пайдено, о/„; N 10,35; С1 17,12CaoH NsSCl .. Вычислено, %: N 10,40; С1 17,66.Paydeno, o / „; N 10.35; C1 17,12CaoH NsSCl .. Calculated,%: N 10.40; C1 17.66.
П р н мер 2. По л у ч е н и е N-(3- (2-п и р ид и л)э т и л -К-О-х л о р ф е н и л - N-ф е н и лт и о м о ч е в и н ы. Смесь 0,5 г моль фенилизотиоцианата , 0,65 г-моль (К-О-хлорфеииламино )этил -пиридина в 200 Л1Л бензола нагревают при 80°С в течение 7-9 час. Реакционную массу охлаждают, отфильтровывают . Сырой продукт обрабатывают 200 мл этанола и отдел ют нерастворившпйс продукт . Выход конечного продукта 85,6о/о; т. пл. 123-125°С.Para 2. Measure 3. N- (3- (2-n and p-id and l) et and l-K-O-hl o r f en and l - N- Fe n i lt and o m o c e n i s. A mixture of 0.5 g mol of phenyl isothiocyanate, 0.65 g mol (KO-chlorfeiyl amino) ethyl pyridine in 200 L1L of benzene is heated at 80 ° C in for 7-9 hours, the reaction mass is cooled, filtered, the crude product is treated with 200 ml of ethanol and the insoluble product is separated. The yield of the final product is 85.6 o / o, mp 123-125 ° C.
Пайдено, о/„: N 11,65; С1 9,864.Paydeno, o / „: N 11.65; C1 9,864.
2525
CoonisNgSClo.CoonisNgSClo.
Вычислено, %: N 11,44; С1 9,650.Calculated,%: N 11.44; C1 9,650.
Предмет изобретени Subject invention
Claims (3)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU197567A1 true SU197567A1 (en) |
Family
ID=
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