SU186484A1 - - Google Patents

Info

Publication number

SU186484A1

SU186484A1 SU1048060A SU1048060A SU186484A1 SU 186484 A1 SU186484 A1 SU 186484A1 SU 1048060 A SU1048060 A SU 1048060A SU 1048060 A SU1048060 A SU 1048060A SU 186484 A1 SU186484 A1 SU 186484A1

Authority

SU

USSR - Soviet Union

Prior art keywords

indole

yield

ethyl

kip

pyridyl

Prior art date

Links

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• SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 8
• -1 3-PYRIDYLETHYL Chemical class 0.000 description 5
• 238000000034 method Methods 0.000 description 5
• PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 4
• RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 4
• KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical class C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 description 3
• DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
• 238000009835 boiling Methods 0.000 description 3
• 235000019441 ethanol Nutrition 0.000 description 3
• 230000003993 interaction Effects 0.000 description 3
• 229910052708 sodium Inorganic materials 0.000 description 3
• 239000011734 sodium Substances 0.000 description 3
• 239000002904 solvent Substances 0.000 description 3
• BHNHHSOHWZKFOX-UHFFFAOYSA-N 2-methyl-1H-indole Chemical compound C1=CC=C2NC(C)=CC2=C1 BHNHHSOHWZKFOX-UHFFFAOYSA-N 0.000 description 2
• KFDVPJUYSDEJTH-UHFFFAOYSA-N 4-ethenylpyridine Chemical compound C=CC1=CC=NC=C1 KFDVPJUYSDEJTH-UHFFFAOYSA-N 0.000 description 2
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
• ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
• 239000003054 catalyst Substances 0.000 description 2
• 238000006243 chemical reaction Methods 0.000 description 2
• ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
• 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
• 229910052700 potassium Inorganic materials 0.000 description 2
• 239000011591 potassium Substances 0.000 description 2
• 239000000047 product Substances 0.000 description 2
• PYFVEIDRTLBMHG-UHFFFAOYSA-N 2,3-dimethyl-1h-indole Chemical compound C1=CC=C2C(C)=C(C)NC2=C1 PYFVEIDRTLBMHG-UHFFFAOYSA-N 0.000 description 1
• QINFEYUJDPHOLM-UHFFFAOYSA-N 2-(2-pyridin-3-ylethyl)-1h-indole Chemical class C=1C2=CC=CC=C2NC=1CCC1=CC=CN=C1 QINFEYUJDPHOLM-UHFFFAOYSA-N 0.000 description 1
• JHZBMACTRVXOOB-UHFFFAOYSA-N 2-ethyl-3-propyl-1h-indole Chemical compound C1=CC=C2C(CCC)=C(CC)NC2=C1 JHZBMACTRVXOOB-UHFFFAOYSA-N 0.000 description 1
• 239000003708 ampul Substances 0.000 description 1
• 230000015572 biosynthetic process Effects 0.000 description 1
• 238000001816 cooling Methods 0.000 description 1
• 229910000365 copper sulfate Inorganic materials 0.000 description 1
• ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
• 238000004821 distillation Methods 0.000 description 1
• 239000000543 intermediate Substances 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
• 229910052753 mercury Inorganic materials 0.000 description 1
• 239000000825 pharmaceutical preparation Substances 0.000 description 1
• 239000002244 precipitate Substances 0.000 description 1
• 239000011541 reaction mixture Substances 0.000 description 1
• 238000000926 separation method Methods 0.000 description 1
• 238000003786 synthesis reaction Methods 0.000 description 1