SU1644038A1 - Method for detection of persons with increased risk for coagulopathy consumption development under hyperthermic treatment - Google Patents
Method for detection of persons with increased risk for coagulopathy consumption development under hyperthermic treatment Download PDFInfo
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- SU1644038A1 SU1644038A1 SU884445780A SU4445780A SU1644038A1 SU 1644038 A1 SU1644038 A1 SU 1644038A1 SU 884445780 A SU884445780 A SU 884445780A SU 4445780 A SU4445780 A SU 4445780A SU 1644038 A1 SU1644038 A1 SU 1644038A1
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- coagulopathy
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- hemocoagulation
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Abstract
Изобретение относитс к медицине , разделу гематологии, терапии и дает возможность диагностировать патологические изменени в системе гемостаза при различных заболевани х с температурной реакцией, при иммуно- коррекции с помощью физических (тер мических) факторов, при использовании естественных неспецифических средств имунной защиты (температурной реакции организма), а также у лиц, наход щихс в экстремальных темпера- турных услови хо Это достигаетс за счет того, что биохимическое определение параметров коагулограммы провод т в режиме инкубации плазмы, соответствующем температуре дра тела человека, наход щегос в состо нии гипертермии. Снижение гемокоагул ци онной и антитромботической активности по сравнению с уровнем, установленным в стандартных температурных услови х, вл етс основанием дл отнесени в группу риска о ДThe invention relates to medicine, the section of hematology, therapy, and makes it possible to diagnose pathological changes in the hemostasis system in various diseases with a temperature reaction, during immune correction using physical (thermal) factors, using natural non-specific means of immune protection. ), as well as in persons in extreme temperature conditions. This is achieved due to the fact that the biochemical determination of the parameters of the coagulogram is t in the mode of incubation of plasma corresponding to the core temperature of the human body, which is in a state of hyperthermia. A decrease in hemocoagulation and antithrombotic activity compared with the level established in standard temperature conditions is a reason to be classified as at risk in D
Description
Изобретение относитс к медицине и касаетс оценки состо ни гемостаза организма человека, наход щегос в экстремальных температурных услови х .The invention relates to medicine and concerns the assessment of the state of hemostasis of a human body in extreme temperature conditions.
Цель изобретени - повышение точности диагностики коагулопатий у лиц, наход щихс в экстремальных темпера- турйых услови х.The purpose of the invention is to improve the accuracy of diagnosing coagulopathy in persons under extreme temperature conditions.
Способ осуществл етс следующим образом.The method is carried out as follows.
Способ включает забор крови, центрифугирование , отделение плазмы, инкубацию образцов плазмы в индивидуальном температурном режиме при 40 и 43СС, после чего биохимически определ ютс параметры коагулограммы„The method includes blood sampling, centrifugation, plasma separation, incubation of plasma samples at individual temperature conditions at 40 and 43CC, after which the parameters of the coagulogram are determined biochemically.
Пример 1. Больной Н., 46 лет, доставлен с диагнозом грипп, токсическа форма Температура в подмышечной впадине 39,8°С, беспокоит головокружение , боли в мышцах, сухой кашель- , при аускультации дыхание жесткое . В св зи с т желым течением заболевани и возможностью развити такого осложнени как пневмони , в патогенезе которой существенную роль играет система гемостаза, в комплекс обследовани данного больного показано включить исследовани гемокоагу- л ции.Example 1. Patient N., 46 years old, delivered with a diagnosis of influenza, toxic form. Temperature in the armpit is 39.8 ° C, worried about dizziness, muscle pain, dry cough, breathing hard at auscultation. In connection with the severe course of the disease and the possibility of developing such a complication as pneumonia, in the pathogenesis of which the hemostatic system plays a significant role, it is shown to include hemocoagulation studies in the complex examination of this patient.
Забор крови провод т из локтевой вены, кровь центрифугируют 10 мин при 1500 обУмин, отдел ют плазму„ КоагуОBlood sampling is carried out from the ulnar vein, the blood is centrifuged for 10 minutes at 1500 rpm, the plasma is separated.
ЈJ
О СО 00About CO 00
лограмму выполн ют с режимом инкубации плазмы, соответствующим температуре дра тела, котора при измерении составила 40,5°С. Данные коа- гулограммы следующие:The log is performed with a plasma incubation mode corresponding to the core temperature, which was 40.5 ° C as measured. The coagulogram data are as follows:
Л/У Л/Ус ТПГ АКТ ПИ ТВ СГ К/К АТ-111 ЭФЭL / U L / U TPG AKT PI TV SG K / K AT-111 EFE
190 340 ,330 5 1.1 10 4 28 85190 340, 330 5 1.1 10 4 28 85
Согласно полученным данным у больного диагностируетс гиперкоагул ци- онное состо ние: ускорено образование протромбиназьц снижена активность антикоагул ционных свойств крови.According to the data obtained, the patient is diagnosed with a hypercoagulable state: the formation of prothrombinases is accelerated and the activity of the anticoagulation properties of the blood is reduced.
Л/У Л/Ус ТПГ АКТ ПИ ТВ С1 К/К АТ-111 ЭФЭ 350 780 600 7 1.1 16 7 35 95 280L / U L / U TPG AKT PI TV S1 K / K AT-111 EFE 350 780 600 7 1.1 16 7 35 95 280
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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SU884445780A SU1644038A1 (en) | 1988-06-20 | 1988-06-20 | Method for detection of persons with increased risk for coagulopathy consumption development under hyperthermic treatment |
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SU884445780A SU1644038A1 (en) | 1988-06-20 | 1988-06-20 | Method for detection of persons with increased risk for coagulopathy consumption development under hyperthermic treatment |
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SU1644038A1 true SU1644038A1 (en) | 1991-04-23 |
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SU884445780A SU1644038A1 (en) | 1988-06-20 | 1988-06-20 | Method for detection of persons with increased risk for coagulopathy consumption development under hyperthermic treatment |
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SU (1) | SU1644038A1 (en) |
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1988
- 1988-06-20 SU SU884445780A patent/SU1644038A1/en active
Non-Patent Citations (1)
Title |
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Иванов Е.П. Диагностика нарушений гемостаза. - Минск: Беларусь, 1983; с. 222. * |
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