SU1616927A1 - Method of producing dispersion of poly-para-aminostyrene - Google Patents

Abstract

The invention relates to the field of chemistry and polymer technology and allows you to create a dispersion of poly-p-aminostyrene with a particle size of 0.6-10 microns, with high monodispersity (polydispersity coefficient 1.008-1.09), which is achieved by heterophase polymerization of p-aminostyrene in aqueous medium containing surfactants, under the action of mineral or organic acids with a pKa of 7–4.76, taken in an amount of 0.1–20.0 wt.% of the monomer, and carrying out the process in the presence of water-miscible organic liquids with dielectric onitsaemostyu 7,8-32,6 taken upon in the amount of 10-80 vol.% relative to the water. 2 tab.

Description

The invention relates to the chemistry and technology of polymers, namely to a method for producing a polyparaminostyle dispersion, and can be used to create reactive carriers, coatings, sorbents.

The purpose of the invention is to obtain dispersions of: polyparaaminostyrene with a particle diameter of 0.6-10.0 MicM and a decrease in the value of the coefficient of polydispersity of particles.

Example 1. In a three-necked flask equipped with a mechanical stirrer and an inert gas inlet, 1.5 ml (1.52 g) of a 1-styrene solution, 18 ml of a methanol solution (32.6) containing 0.189 g of polyvinylpyrrolidone and 0544 g alklbenzyl dimethylammonium chloride (katamine DB), and 12 mp distilled water. Then, with stirring, add 0.63 ml of 2N. an aqueous solution of hydrochloric acid (pKd 7, 10 mol.%). The polymerization is carried out with stirring, at a temperature of 61 ° C. .

The properties of the dispersion are given in Table I.

EXAMPLE 2 The process is carried out analogously to example 1, but instead of hydrochloric acid, 0.072 ml (10 mol.% Of the monomer amount) of glacial acetic acid (pKQ 4.76) are taken.

Froze The process is carried out similarly to Example 1, but instead of hydrochloric acid, 0.078 g (10 mol.% Of the amount of monomer) is taken.

ABOUT

ABOUT

boric acid (pK-d 9,24) in the form of a solution in distilled water.

Example 4. Similar to Example 1, but the acids take 0.0063 ml (0.1 mol.% Of the amount of monomer). EXAMPLE 5: The process is carried out on a paprimer. 1, but acids take 0.00063 ml (0.01 mol.% Of the amount of monomer). Polymerization practically does not occur, no polymer dispersion is formed.

EXAMPLE 6 The process is carried out as in Example 1, but the acids take 1.26 ml (20 mol.% Of the amount of monomer).

Example. The process is carried out as in example 1, but the acids take 1.58 ml (25 mol.% Of the amount of monomer). No dispersion is formed, since the resulting polymer is soluble in the dispersion medium.

PRI me R 8. In a three-necked flask equipped with a mechanical stirrer and an inert gas inlet, 0.3 ml (3.04 g) p-aminostyrene, 27 ml of an aqueous solution containing 0.2 g of polyvinyl alcohol and 0.068 g of cetylpyridinium bromide are placed. , and 3 ml of tetrahydrofuran (g. - 7.8). Then, with stirring, 0.13 ml (10 mol.% Of the amount of monomer) of 2N hydrochloric acid is added.

PRI me R 9. The process is carried out analogously to example 8, but tetrahydrofuran is taken 1.5 ml (5% by volume relative to water).

Example 10. The process is carried out analogously to example 1, but taking 24 MP (80% by volume relative to water) of a methanol solution containing 2.52 g of polyvinylpyrrolidone, 0.072 g of catamin AB and 6 ml of distilled water.

Example 11. The process is carried out analogously to example 1, but taking 27 Nm (90 vol.% Relative to water) of a methanol solution containing 2.83 g of polyvinylpyrrolidone, 0.081 g of catamine AB and 3 ml of distilled water. A dispersion is not formed, since the resulting polymer is soluble in dispersion water.

PRI me R 12 (comparative prototype). In a three-necked flask equipped with a mechanical stirrer and an inert gas inlet a, 30 ml of a 0.05% aqueous solution of polyvinyl alcohol, then 3 ml of p-aminostyrene and 0.03 g of a radical initiator of 2,2-azodiisobutyronitrile are mixed, the mixture is mixed 30 min, then stirring is stopped and the flask is placed in a water bath heated to 50 ° C.

PRI me R 13 (control). The process is carried out similarly to Example 8, but instead of tetrahydrofuran, 3 ml of ethyl acetate (10% by volume) are taken with E 6.02.

Example 14 (control). The process is carried out similarly to the example

RU 1 but instead of methanol take 12 ml of an aqueous solution of surfactant and 18 ml of glycerin (5 42.5).

Properties of dispersions are listed in Table 1.

Example 15 (comparative).

To 250 mg of polystyrene latex (particle diameter 1.8 µm) in 0.5 ml of PBS buffer with a pH of 6.0, 500 mg of gelatin dissolved in

in 20 ml of the same buffer, and the mixture is stirred at room temperature for 3 hours, then placed overnight in a refrigerator at. Latex-gelatin conjugates are isolated by centrifugation and washing with PBS, pH 7.4. ; :

Properties of the conjugate are shown in table 2.

P r and measures 16. To 250 mg of a poly-p-aminobasminol latex (particle diameter 2.0 µm) in 0.5 ml of PBS buffer with a pH of 6.0, 10 µl of a 50% aqueous solution of glutaraldehyde was added with stirring. and immediately

500 mg of gelatin dissolved in 20 ml of the same buffer. Next, the process is carried out according to Example 15.

Properties of conjugate are given in table 2.

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Claims (1)

Formula of Presence The method of obtaining poly-para-aminostyrene dispersion by heterophase polymerization of para-aminostyrene in an aqueous medium containing surfactants, characterized in that, in order to obtain a dispersion of polyparaamylenol with a particle diameter of 0.6-10.0 µm and reduce the particle polydispersity coefficient, the polymerization is carried out under the action of O, 1-20.0 mol.% from para-aminostyrene mineral or organic acids with a pK 7,001616927 water-miscible organic, 76, and the process is carried out in presence liquids with a dielectric constant of 10-80% by volume with a penetrability of 7.8-32.6. . T a b l and c a I Example Polymerization time, h 1.5 2.0 3 (contra.) 1, 5 10.0 0.6 3.2 1.2 1.01 1.09 1.03 1.4 1.008 Light yellow Not formed Bela Does not form Bela Bela Bela Not formed 45.0 5 (counter) 60, 75 7 (counter) 83, 0 9 (contra.) 3.0 10 11 (cocktail) 12 (cf. - on the prototype) 8.0 100.0 1.9 Yellow 13 (contra) 3.0 1.1 1, b 14 (contra) 3.0 0.5 2.0 2.0 Emulsion emulsion system; .la Table 2 System Protein Contents 2-pro 3- pro 4-pro 1 mon- I 2 months. washing washing storage- I storage | S25 Gelatin-polystyrene +. + + + 4- Gelatin -poly-p- -aminostyrol + + - - The + sign indicates the presence of protein in the eluates; familiar - his absence. Compiled by L. Chupova Editor I. Kishtulinets Tekhred. L. Oliynyk Proofreader I. Muska Order 835 Circulation 317 Subscription VNIIPI State Committee for Inventions and Discoveries at the State Committee on Science and Technology of the USSR 113035, Moscow, Zh-35, Raushsk nab. 4/5  J, -, -1-g- - ..- D «AND Production and publishing plant Patent, Uzhgorod, st. Gagarin, 101 Polydispersity coefficient, Kj, Color dispersion 1.02 1.008 1.01 1.09 1.03 1.4 1.008 Bela Bela Not formed Light yellow Not formed Bela Does not form Bela Bela Bela Not formed