SU1599001A1 - Method of applying coating on artificial lens of eye - Google Patents

Abstract

This invention relates to medicine, ophthalmology, and is intended for the implantation of an artificial eye lens (IC). In order to reduce trauma to the eye tissues, after treatment with 10% sodium hydroxide solution, they are washed with distilled water for 15-20 minutes and dried. Then a solution of dexazone (10 µl) is applied to THEIR eyes, dried for 1 h at 37 ° C, re-applied with the same solution (10 µl) and incubated for 1.5-2.0 h at 37 ° C. This forms a gel with a water content of 10-30% and dexazone 90-70%. Gel-coated ICs are stored in sealed containers in light-tight cases at room temperature. Traumatization of the eye is reduced by 2 times.

Description

The invention relates to medicine, namely to ophthalmology, and can be used in the implantation of an artificial eye lens.

The aim of the invention is to reduce trauma to the tissues of the eye.

The method is carried out in the following way.

After pretreatment with 10% sodium hydroxide solution for 15-20 minutes to remove mechanical impurities from the surface, the artificial lens of the eye is washed with distilled water and air dried. Then, a dexazone solution in a volume of 10 µl is applied to the artificial lens of the eye, dried for 1 hour at 37 ° C, then a solution of dexazone 10 µl is applied again and maintained at 37 ° C for 1.5-2 hours, thus forming gel with a water content of 10-30% and dexazone 90-70%. The water content in the control sample of the lens (one of serine 10 cm) is determined by weight loss when n; 1 heating the lenses at 100 ° C until it reaches a constant weight. The gel coating of the lenses is stored in sealed containers with a coherent temperature in light-transparent cases. Example 1

Solution volume, mkl10

Time of first drying, part 1 Temperature, ° С 37 Volume of solution at. re-coating, µl - 10 Time re-drying, h1,5 Temperature, ° С 37 Water content

in gel,%

thirty

cl

with so

Loss of endothelial cells during the operation on the implantation of the lens of the satavil 10%, i.e. 2 times less than in the control eye (20%), which indicates a significant reduction in injury to eye tissue. Example 2

Solution volume, mkl10

Time of first drying, h1 Temperature, ° C 37 Volume of solution during re-coating, μL 10 Time of repeated drying, h 2 Temperature, ° C 37 Water content in gel,% 10 Loss of endothelial cells during surgery was 11%, i.e. 2 times less than in the control eye (22.5%). The cornea in the postoperative period is transparent. During the first two days after surgery, a corneal stroma of grade I-II was observed in the control eye. Example 3

Solution volume, mkl10

Time of first drying, part 1 Temperature, ° C 37 Volume of solution during re-coating, μl 10 Time of repeated drying, part 1.75

Temperature, ° С37

Water content

in gel,% 20

The loss of endothelial cells during surgery was 9%, i.e., 2.5 times less than in the control eye (23.5%). The cornea in the postoperative period is transparent. In the control eye, on the background of the absence of acute postoperative inflammation on the first day after surgery, edema of the endothelium and corneal epithelium was observed.

Compared to the base case, the use of the invention allows to reduce the trauma of eye tissue by 2 times.

Claims (1)

Invention Formula The method of coating the artificial lens of the eye, including applying to the surface in contact with the endothelium of the cornea of the eye, the gel-forming substance in the amount held by this surface, and drying, characterized in that, in order to reduce the trauma of the eye tissues, the substance is gel-forming applied twice, while the artificial lens is dried at 37 ° C after the first application of the substance for 1 hour, and after the second - for 1.5-2.0 hours.