BRPI0416037A - processes and devices for treating epithelium - Google Patents

processes and devices for treating epithelium

Info

Publication number
BRPI0416037A
BRPI0416037A BRPI0416037-1A BRPI0416037A BRPI0416037A BR PI0416037 A BRPI0416037 A BR PI0416037A BR PI0416037 A BRPI0416037 A BR PI0416037A BR PI0416037 A BRPI0416037 A BR PI0416037A
Authority
BR
Brazil
Prior art keywords
delamination
eye
epithelium
devices
treatment
Prior art date
Application number
BRPI0416037-1A
Other languages
Portuguese (pt)
Inventor
Edward Perez
Original Assignee
Tissue Eng Refraction Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissue Eng Refraction Inc filed Critical Tissue Eng Refraction Inc
Publication of BRPI0416037A publication Critical patent/BRPI0416037A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
    • A61F9/0133—Knives or scalpels specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872—Cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Abstract

"PROCESSOS E DISPOSITIVOS PARA TRATAMENTO DE EPITéLIO". A presente invenção refere-se a métodos e dispositivos para tratamento de um olho, onde um retralho epitelial foi gerado pelo olho por delaminação epitelial. Alguns dos métodos de tratamento compreendem a administração de um agente de tratamento efetivo para uma córnea, epitélio ou olho, antes, durante e depois da delaminação. Diversos agentes de tratamento são descritos. Exemplos de agentes de tratamento incluem moléculas de adesão, lubrificantes, agentes de nutrição, fatores de crescimento e similares. Outros métodos de tratamento e os dispositivos para tais tratamentos descritos envolvem resfriamento do olho, epitélio ou córnea antes, durante ou depois da delaminação. Em algumas variações, a etapa de resfriamento compreende o resfriamento de um dispositivo de delaminação a uma temperatura efetiva durante a delaminação. Em outras variações, a etapa de resfriamento compreende introduzir um fluido de resfriamento no olho, epitélio ou córnea antes, durante ou depois da delaminação. Outros métodos descritos envolvem a modificação de uma lente de contato de bandagem, e a introdução de células epiteliais intactas ao retralho epitelial."EPITHELIUM TREATMENT PROCESSES AND DEVICES". The present invention relates to methods and devices for treating an eye, where an epithelial patch has been generated by the eye by epithelial delamination. Some of the treatment methods include administering an effective treatment agent to a cornea, epithelium or eye before, during and after delamination. Several treatment agents are described. Examples of treatment agents include adhesion molecules, lubricants, nutrition agents, growth factors and the like. Other treatment methods and devices for such treatments described involve cooling of the eye, epithelium or cornea before, during or after delamination. In some variations, the cooling step comprises cooling a delamination device to an effective temperature during delamination. In other variations, the cooling step comprises introducing a cooling fluid into the eye, epithelium or cornea before, during or after delamination. Other methods described involve modifying a bandage contact lens and introducing intact epithelial cells into the epithelial flap.

BRPI0416037-1A 2003-11-14 2004-11-15 processes and devices for treating epithelium BRPI0416037A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51990303P 2003-11-14 2003-11-14
PCT/US2004/038186 WO2005049071A2 (en) 2003-11-14 2004-11-15 Epithelium treatment methods and devices for treating the epithelium

Publications (1)

Publication Number Publication Date
BRPI0416037A true BRPI0416037A (en) 2007-01-02

Family

ID=34619393

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416037-1A BRPI0416037A (en) 2003-11-14 2004-11-15 processes and devices for treating epithelium

Country Status (10)

Country Link
EP (1) EP1706080A2 (en)
JP (1) JP2007511293A (en)
KR (1) KR20060126971A (en)
CN (1) CN1905847A (en)
AU (1) AU2004291138A1 (en)
BR (1) BRPI0416037A (en)
CA (1) CA2545885A1 (en)
IL (1) IL175579A0 (en)
MX (1) MXPA06005434A (en)
WO (1) WO2005049071A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024035A1 (en) 2002-09-13 2004-03-25 Ocular Sciences, Inc. Devices and methods for improving vision
WO2007123644A2 (en) * 2006-03-28 2007-11-01 Tissue Engineering Refraction, Inc. Partially lubricious epithelial delaminator
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
GB0620537D0 (en) * 2006-10-17 2006-11-22 Univ Southampton Copolymers suitable for use in corneal bandages
US8242076B2 (en) * 2007-08-15 2012-08-14 Ramot At Tel-Aviv University Ltd. Polypeptides, matrices, hydrogels and methods of using same for tissue regeneration and repair
US10342697B2 (en) 2016-04-13 2019-07-09 Avedro, Inc. Systems and methods for delivering drugs to an eye

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012131A1 (en) * 1992-11-20 1994-06-09 Shinseiro Okamoto Cornea operating method and apparatus
IT1325891B (en) * 2001-06-22 2004-12-30 Abb Service Srl MINIATURIZED SWITCH POLO
MXPA04006954A (en) * 2002-01-17 2005-03-23 Perez Edward Methods for producing epithelial flaps on the cornea and for placement of ocular devices and lenses beneath an epithelial flap or membrane, epithelial delaminating devices, and structures of epithelium and ocular devices and lenses.

Also Published As

Publication number Publication date
JP2007511293A (en) 2007-05-10
KR20060126971A (en) 2006-12-11
WO2005049071A3 (en) 2005-11-17
CN1905847A (en) 2007-01-31
EP1706080A2 (en) 2006-10-04
WO2005049071A2 (en) 2005-06-02
IL175579A0 (en) 2006-09-05
MXPA06005434A (en) 2007-01-25
CA2545885A1 (en) 2005-06-02
AU2004291138A1 (en) 2005-06-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.