SU1392589A1 - Method of simulating an abscess - Google Patents

Description

(21) 4093069 / 28-14

(22) 07/18/86

(46) 04/30/88. Bul Number 16

(71) 1st Moscow Medical Institute. I.M. Sechenov

(72) L. A. Mamedov, A. V. Nikolaev,

E. Yunuskhodzhaev, V.V. Zakharov, V.N. Galankin, N.A. Semenova, N.B. Grishina

and N. D. Egorova

(53) 615.478 (088.8)

(56) Grishina I. A., Galankin V.N., - Zh.

microbiol., epidemiol. and I. immunobiologist.,

I982, No. 2, p. 82-85.

(54) METHOD OF MODELING ABSCESS

(57) The invention relates to medicine. To increase the reproducibility of the model, muscle is injured. A day later, a gauze ball soaked in blood and a suspension of pathogenic microflora was introduced into the muscle pocket. An abscess develops in 100% of cases.

Ltd

N5 SL

00

with

The invention relates to medicine, in particular to experimental surgery and pathophysiology, and can be used in scientific research to create an abscess.

The aim of the invention is to increase the reproducibility of the model.

The method is realized in the following way.

The pulpoextractor to a depth of 1.3-1.6 cm is introduced into the muscle straightening muscle of the experimental animal and, if it is rotated at an angle, injures the bone, then a day later, in a puncture site, the surgical access is exposed to my neck. bluntly, they create a pocket, introduce a gauze laryx with a diameter of 10-12 mm, previously soaked in blood and a suspension of matogenic microflora, and sew up the wound.

Example. A 1% hexenal solution was injected into the ear vein of the rabbit. Then, an indent of 3 cm from the line connecting the spinous processes of the spine, between II and III in the lumbar vertebrae, the injection needle was inserted into the muscle of the spinal cord to a depth of 1.3 cm and, rotating with its 45 ° angle,

and

ten

15

20

injure muscle. Then, after 24 hours, at the puncture site parallel to the body axis, cut the skin 1.4 cm long, the tip of the clamp is inserted into the muscle 1.3 cm deep and bluntly thicker in the muscle creates a pocket into which a gauze ball 10 mm in diameter with a suspension is inserted daily culture of pathogenic staphylococcus in concentration of 1, microbial bodies and soaked in the blood of an experimental animal. By day 7, an abscess develops in 100%, according to the clinical and morphological characteristics, the identical form of abscess in humans.

Claims (1)

Invention Formula The method of modeling an abscess by introducing a gauze ball with a culture of staphylococcus into tissue with subsequent wound closure, characterized in that, in order to increase the reproducibility of the model, a pulpoextractor is injected intramuscularly and injures the muscle, then after a day, soft tissues are dissected at the puncture site, soft tissues are exposed, in its thickness, a pocket is created in an ad hoc way and a gauze ball soaked in blood is introduced into it.