SU1228861A1 - Method of obtaining agent possessing wound-healing activity - Google Patents
Method of obtaining agent possessing wound-healing activity Download PDFInfo
- Publication number
- SU1228861A1 SU1228861A1 SU843826857A SU3826857A SU1228861A1 SU 1228861 A1 SU1228861 A1 SU 1228861A1 SU 843826857 A SU843826857 A SU 843826857A SU 3826857 A SU3826857 A SU 3826857A SU 1228861 A1 SU1228861 A1 SU 1228861A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- healing activity
- agent possessing
- obtaining agent
- wound
- possessing wound
- Prior art date
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- Medicines Containing Plant Substances (AREA)
Description
Изобретение относитс к химико-фармацевтическому производству, а именно к сно- собам получени лекарственных средств из растительного сырь .The invention relates to chemical and pharmaceutical production, in particular, to drugs for the production of drugs from plant raw materials.
Цель изобретени - повышение рано- заживл ющей способности за счет использовани в качестве исходного сырь листьев д гил низбегающего.The purpose of the invention is to increase the wound healing ability by using as a raw material the leaves of dil gilding.
Способ осуществл етс путем экстракции листьев д гил низбегающего этиловым спиртом с последующим упариванием экстракта .The method is carried out by extracting the leaves with an ethyl alcohol and then evaporating the extract.
Пример. 180 кг высущенных и измельченных листьев д гил низбегающего экстрагируют этиловым спиртом методом многократной реперкол ции до отрицательной пробы на 7-метокси-8-изопентенилкумарин (остол).Example. 180 kg of dried and crushed leaves are extracted and then extracted with ethyl alcohol by repeated repercolation to a negative sample for 7-methoxy-8-isopentenylcoumarin (Ostol).
Отсутствие остола в элюате устанавливают методом тонкослойной хроматографииThe absence of Ostol in the eluate is established by thin layer chromatography.
на окиси алюмини в системе гексан-хлоро- форм (2 : 3) по исчезновению на хромато- грамме при ультрафиолетовом облучении голубого п тна с Rf 0,86, объединенные извлечени упаривают в вакууме. Получают 20,57 кг экстракта, который используют дл получени 5%-ной мази на основе ланолин-вазелин (1:9). В таблице приведены сравнительные данные ранозажив.1 ющей активности экстракта из листьев и корней д гил низбегающего.on alumina in the hexane-chloroform system (2: 3) after the disappearance of a blue spot with Rf 0.86 on the chromatogram under UV irradiation, the combined extracts are evaporated in vacuo. 20.57 kg of extract is obtained, which is used to obtain a 5% lanolin-petrolatum ointment (1: 9). The table shows the comparative data on the wound healing activity of the extract from the leaves and roots of the dammer.
ПоказателиIndicators
Токсичность, мг/кг Сроки полного заживлени поражений , сутToxicity, mg / kg Terms of complete healing of lesions, days
ЭкстрактExtract
из листьевиз корнейfrom leaves of roots
5ПП5PP
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU843826857A SU1228861A1 (en) | 1984-12-18 | 1984-12-18 | Method of obtaining agent possessing wound-healing activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU843826857A SU1228861A1 (en) | 1984-12-18 | 1984-12-18 | Method of obtaining agent possessing wound-healing activity |
Publications (1)
Publication Number | Publication Date |
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SU1228861A1 true SU1228861A1 (en) | 1986-05-07 |
Family
ID=21152157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU843826857A SU1228861A1 (en) | 1984-12-18 | 1984-12-18 | Method of obtaining agent possessing wound-healing activity |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU1228861A1 (en) |
-
1984
- 1984-12-18 SU SU843826857A patent/SU1228861A1/en active
Non-Patent Citations (1)
Title |
---|
Храмов В. Г., Р бых Л. Д., Рогачев М. В, Каткова Е. Б., Милевский Е. И., Храмова Г. Г. Лечение экспериментальных поверхностных ран у крыс препаратами растительного происхождени и оценка их эффективности.- Актуальные вопросы оказани и совер- 1иенствовани хирургической Л1о.1ош.и на во- епно-.морском флоте. Тезисы докл. научной конференции. Л., 1984, с. 36-37. * |
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