SU1228861A1 - Method of obtaining agent possessing wound-healing activity - Google Patents

Method of obtaining agent possessing wound-healing activity Download PDF

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Publication number
SU1228861A1
SU1228861A1 SU843826857A SU3826857A SU1228861A1 SU 1228861 A1 SU1228861 A1 SU 1228861A1 SU 843826857 A SU843826857 A SU 843826857A SU 3826857 A SU3826857 A SU 3826857A SU 1228861 A1 SU1228861 A1 SU 1228861A1
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SU
USSR - Soviet Union
Prior art keywords
healing activity
agent possessing
obtaining agent
wound
possessing wound
Prior art date
Application number
SU843826857A
Other languages
Russian (ru)
Inventor
Леонид Дмитриевич Рябых
Нина Ивановна Шипулина
Василий Георгиевич Храмов
Галина Георгиевна Храмова
Михаил Васильевич Рогачев
Original Assignee
Военно-Медицинская Ордена Ленина Краснознаменная Академия Им.С.М.Кирова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Военно-Медицинская Ордена Ленина Краснознаменная Академия Им.С.М.Кирова filed Critical Военно-Медицинская Ордена Ленина Краснознаменная Академия Им.С.М.Кирова
Priority to SU843826857A priority Critical patent/SU1228861A1/en
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Publication of SU1228861A1 publication Critical patent/SU1228861A1/en

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Description

Изобретение относитс  к химико-фармацевтическому производству, а именно к сно- собам получени  лекарственных средств из растительного сырь .The invention relates to chemical and pharmaceutical production, in particular, to drugs for the production of drugs from plant raw materials.

Цель изобретени  - повышение рано- заживл ющей способности за счет использовани  в качестве исходного сырь  листьев д гил  низбегающего.The purpose of the invention is to increase the wound healing ability by using as a raw material the leaves of dil gilding.

Способ осуществл етс  путем экстракции листьев д гил  низбегающего этиловым спиртом с последующим упариванием экстракта .The method is carried out by extracting the leaves with an ethyl alcohol and then evaporating the extract.

Пример. 180 кг высущенных и измельченных листьев д гил  низбегающего экстрагируют этиловым спиртом методом многократной реперкол ции до отрицательной пробы на 7-метокси-8-изопентенилкумарин (остол).Example. 180 kg of dried and crushed leaves are extracted and then extracted with ethyl alcohol by repeated repercolation to a negative sample for 7-methoxy-8-isopentenylcoumarin (Ostol).

Отсутствие остола в элюате устанавливают методом тонкослойной хроматографииThe absence of Ostol in the eluate is established by thin layer chromatography.

на окиси алюмини  в системе гексан-хлоро- форм (2 : 3) по исчезновению на хромато- грамме при ультрафиолетовом облучении голубого п тна с Rf 0,86, объединенные извлечени  упаривают в вакууме. Получают 20,57 кг экстракта, который используют дл  получени  5%-ной мази на основе ланолин-вазелин (1:9). В таблице приведены сравнительные данные ранозажив.1 ющей активности экстракта из листьев и корней д гил  низбегающего.on alumina in the hexane-chloroform system (2: 3) after the disappearance of a blue spot with Rf 0.86 on the chromatogram under UV irradiation, the combined extracts are evaporated in vacuo. 20.57 kg of extract is obtained, which is used to obtain a 5% lanolin-petrolatum ointment (1: 9). The table shows the comparative data on the wound healing activity of the extract from the leaves and roots of the dammer.

ПоказателиIndicators

Токсичность, мг/кг Сроки полного заживлени  поражений , сутToxicity, mg / kg Terms of complete healing of lesions, days

ЭкстрактExtract

из листьевиз корнейfrom leaves of roots

5ПП5PP

Claims (1)

СПОСОБ ПОЛУЧЕНИЯ СРЕДСТВА, ОБЛАДАЮЩЕГО РАНОЗАЖИВЛЯЮЩЕЙ АКТИВНОСТЬЮ путем экстракции дягиля низбегающего (Archangelica deccureus) спиртом и упаривания экстракта, отличающийся тем, что, с целью повышения активности, в качестве источника сырья используют листья растения.METHOD FOR PRODUCING AN EQUIPMENT WITH WELL-HEALING ACTIVITY by extraction of angelica down-flowing (Archangelica deccureus) with alcohol and evaporation of the extract, characterized in that, in order to increase activity, plant leaves are used as a source of raw materials. ю го QO оyu qo o
SU843826857A 1984-12-18 1984-12-18 Method of obtaining agent possessing wound-healing activity SU1228861A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU843826857A SU1228861A1 (en) 1984-12-18 1984-12-18 Method of obtaining agent possessing wound-healing activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU843826857A SU1228861A1 (en) 1984-12-18 1984-12-18 Method of obtaining agent possessing wound-healing activity

Publications (1)

Publication Number Publication Date
SU1228861A1 true SU1228861A1 (en) 1986-05-07

Family

ID=21152157

Family Applications (1)

Application Number Title Priority Date Filing Date
SU843826857A SU1228861A1 (en) 1984-12-18 1984-12-18 Method of obtaining agent possessing wound-healing activity

Country Status (1)

Country Link
SU (1) SU1228861A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Храмов В. Г., Р бых Л. Д., Рогачев М. В, Каткова Е. Б., Милевский Е. И., Храмова Г. Г. Лечение экспериментальных поверхностных ран у крыс препаратами растительного происхождени и оценка их эффективности.- Актуальные вопросы оказани и совер- 1иенствовани хирургической Л1о.1ош.и на во- епно-.морском флоте. Тезисы докл. научной конференции. Л., 1984, с. 36-37. *

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