SU1137698A1 - Process for preparing cis- diaminodichlorodihydroxoplatinum(iv) - Google Patents

Process for preparing cis- diaminodichlorodihydroxoplatinum(iv)

Info

Publication number
SU1137698A1
SU1137698A1 SU3651749/26A SU3651749A SU1137698A1 SU 1137698 A1 SU1137698 A1 SU 1137698A1 SU 3651749/26 A SU3651749/26 A SU 3651749/26A SU 3651749 A SU3651749 A SU 3651749A SU 1137698 A1 SU1137698 A1 SU 1137698A1
Authority
SU
USSR - Soviet Union
Prior art keywords
cis
diaminodichlorodihydroxoplatinum
desired product
diaminodichloroplatinum
preparing cis
Prior art date
Application number
SU3651749/26A
Other languages
Russian (ru)
Inventor
Н.Н. Желиговская
Е.П. Красовская
Original Assignee
МГУ им. М.В.Ломоносова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by МГУ им. М.В.Ломоносова filed Critical МГУ им. М.В.Ломоносова
Priority to SU3651749/26A priority Critical patent/SU1137698A1/en
Application granted granted Critical
Publication of SU1137698A1 publication Critical patent/SU1137698A1/en

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

FIELD: medicine. SUBSTANCE: process for preparing cis- diaminodichlorodihydroxoplatinum (IV) comprises treating cis-diaminodichloroplatinum (II) suspension with 25-30 hydrogen peroxide, separating solid residue, dissolving it in mineral acid and precipitating the desired product. Cis-diaminodichloroplatinum (II) is treated at 60-80 C. Mineral acid is sulfuric or phosphoric acid and the desired product is precipitated with alkali. EFFECT: improved purity of the desired product.
SU3651749/26A 1983-10-17 1983-10-17 Process for preparing cis- diaminodichlorodihydroxoplatinum(iv) SU1137698A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU3651749/26A SU1137698A1 (en) 1983-10-17 1983-10-17 Process for preparing cis- diaminodichlorodihydroxoplatinum(iv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU3651749/26A SU1137698A1 (en) 1983-10-17 1983-10-17 Process for preparing cis- diaminodichlorodihydroxoplatinum(iv)

Publications (1)

Publication Number Publication Date
SU1137698A1 true SU1137698A1 (en) 1996-09-27

Family

ID=60539134

Family Applications (1)

Application Number Title Priority Date Filing Date
SU3651749/26A SU1137698A1 (en) 1983-10-17 1983-10-17 Process for preparing cis- diaminodichlorodihydroxoplatinum(iv)

Country Status (1)

Country Link
SU (1) SU1137698A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066526A1 (en) * 2002-02-05 2003-08-14 'immcont' Gmbh & Kg 'pharmoplatina' Method for producing platinum complexes (iv)
EP1524273A1 (en) * 2003-10-13 2005-04-20 Salama, Zoser B. nat.rer.Dr. Process for the preparation of trans- or cis-diammoniumdichlorodihydroxyplatinum(IV) salts and derivatives and their use for the preparation of pharmaceutical active agents
JP2007508331A (en) * 2003-10-13 2007-04-05 サラマ，ゾーセル，ベー． Pharmaceutical composition comprising oxoplatin, its salts and derivatives

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066526A1 (en) * 2002-02-05 2003-08-14 'immcont' Gmbh & Kg 'pharmoplatina' Method for producing platinum complexes (iv)
EP1524273A1 (en) * 2003-10-13 2005-04-20 Salama, Zoser B. nat.rer.Dr. Process for the preparation of trans- or cis-diammoniumdichlorodihydroxyplatinum(IV) salts and derivatives and their use for the preparation of pharmaceutical active agents
WO2005040045A2 (en) * 2003-10-13 2005-05-06 Salama Zoser B Method for the production of trans- or cis-diammoniumdichlorodihydroxoplatinum (iv) and use thereof for the production of pharmaceutical agent
JP2007508331A (en) * 2003-10-13 2007-04-05 サラマ，ゾーセル，ベー． Pharmaceutical composition comprising oxoplatin, its salts and derivatives
JP2007513066A (en) * 2003-10-13 2007-05-24 サラマ，ゾーセル，ベー． Process for the preparation of trans- or cis-diammonium dichlorodihydrooxoplatinum (IV) and its use in the manufacture of pharmaceutically active substances
US7687651B2 (en) 2003-10-13 2010-03-30 Riemser Arzneimittel Ag Method for the preparation of trans-or cis-diammoniumdichlorodihydroxoplatinum(IV) and the use thereof in the production of pharmaceutical active substances
JP4707668B2 (en) * 2003-10-13 2011-06-22 リエムザー アルズナイミッテル エージー Pharmaceutical composition comprising oxoplatin, its salts and derivatives
JP4887153B2 (en) * 2003-10-13 2012-02-29 リエムザー アルズナイミッテル エージー Process for the preparation of trans- or cis-diammonium dichlorodihydrooxoplatinum (IV) and its use in the manufacture of pharmaceutically active substances

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