SU1097321A1 - Method of treatment of eye diseases - Google Patents

Abstract

METHOD OF TREATING EYE DISEASES, involving sound vibrations and drug therapy, characterized in that, in order to shorten the treatment time, the eye block and orbit tissues are affected by infrasonic vibrations with a frequency of 2-6 Hz, the intensity of 135-165 dB during 10-15 minutes in a course of 10-15 days.

Description

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The invention relates to medicine, namely to ophthalmology, and can be used to treat diseases of the anterior, middle and posterior segments of the eye. A known method of treating diseases of the eye, which involves exposure to sound vibrations and drug therapy 1. The effectiveness of a known method of treatment is insufficient, especially in diseases of the posterior segment of the eye, due to the rapid attenuation of ultrasonic vibrations (US) in tissues that are used in the known method ; Ultrasound also quickly decays in gas, aerosol dosage forms, which excludes their combined use. In addition, contact of the radiator with the eye unit, which is necessary in the treatment of ultrasound, requires the use of anesthesia. This leads to listening to the epithelium, to the disintegration of the mucous membrane, which in a number of cases with increased sensitivity precludes the use of ultrasound. The purpose of the invention is to reduce the duration of treatment. The goal is achieved by the fact that according to the method of treating eye diseases, which involves sound vibrations and medical therapy, the eyeblock and orbit tissues are affected by infrasonic vibrations with a frequency of 2-6 Hz, with an intensity of 135-165 dB for 10-15 min in course of 10 - 15 days. The method is carried out as follows. A medicinal product is injected into the eye and infused with red vibrations with a frequency of 2-6 Hz, an intensity of 135 165 dB for 10-15 minutes in a course of 10-15 days. The choice of exposure parameters is explained by the fact that lowering the frequency of infrasound below 2 Hz or exceeding its higher than 6 Hz slows down the absorption of copper copper, and lowering the intensity of infrasound less than 135 dB decreases the effect. An intensity of more than 165 dB is undesirable due to the occurrence of unpleasant sensations in a patient and an increase in mechanical stress on the eye tissue. Example 1. A shinkle breed rabbit weighing 2.5 kg weighing 0.4 mm was injected into the retrobulbar space of both eyes. The right eye was exposed to infrasound, the mean pressure of which was set below the normobaric pressure (in the suction mode) to create a flow of drugs from the retrobulbar space to the posterior segment of the eye. Influenced by infrasonic vibrations for 15 min with a frequency of 4 Hz, 165 dB power. The left eye served as a control. After the procedure, both eyes were removed and the pharmacokinetics, cavinton in eye tissue and optic nerve tissue were examined. Infrasound exposure creates directional movement of drugs from the retrobulbar space into the optic nerve, sclera, vitreous body, choroid and retina, accelerating the penetration and increasing their concentration in eye tissues 2-3 times more compared to the control eye. Example 2. Volunteer K .., 27 years old. Almost healthy. To test the absorbability of the drugs, 2 drops of 1% polycarpine solution were instilled into both eyes. After that, the right eye was affected by infrasonic oscillations (OF) for 10 min, the average pressure of infrasonic oscillations was set higher than the normobaric pressure, creating an injection at a frequency of 6 Hz and a power of 135 dB. The change in pupil width in both eyes was measured before exposure IZ, immediately after the procedure, 10, 20, 30 minutes after it. The left eye served as a control. The following data was obtained: Baseline 6.0 6.0 After the procedure 5.75 5.5 Through The given example shows an increase in the effectiveness of pilocarpine under the influence of infrasound. Example 3. Patient B., 61 years old, Since 1968 he has been treated for atrophy of the optic nerve in both eyes, an initial cataract of the left eye. Regularly, 1-2 times a year, he was treated under inpatient conditions. The vision of the right eye during the time of observation remained at the level of 0.1-0.2. Upon receipt, the visual acuity of the right eye is 0.05 e + 3, OD 0.1, and the visual acuity of the left eye - 0.02 is not corrected. The right eye was treated with infrasound in combination with Cavinton. The use of retrobulbar injections of cavinton increased the vision of the right eye to 0.2 with correction (not complete). Subsequently, the treatment included IZ after the injection of Cavinton (0.5 ml) for 10 minutes. The average pressure was set at the level of hypobaric D frequency 2 Hz, power 135 dB, treatment was carried out for 5 days. There were no complications. After treatment acuity

the sight of the right eye has risen to 0.08 with holes. + 3.0 D 0.3.

Thus, a positive effect was noted from the treatment by the proposed method in a patient who had previously been treated without modern medicine for more than 12 years.

Example 4. Patient M., 28 years old. Found the second day in the hospital with a diagnosis of acute iridocyclitis of the left eye. The eye is sharply irritated, the pericorneal injection is pronounced, the anterior chamber moisture is opalescent, the iris is swollen and the tendency to develop posterior synechiae is 12-5 hours, the pupil is 4.5 mm, scalloped. Frequent instillations, mydriatics, injections of adrenaline and atropine prevented the breaking of synechia. IZ was added to treatment after instillation of adrenaline, cocaine and atropine. The average pressure of the oscillations was set at the level of normobaric, frequency 4 Hz, power 150 dB. The use of infrasound increased the effect of mydriatics and led to the rupture of the posterior synechias.

The invention makes it possible not only to significantly increase the effectiveness of local effects of medications, but also to apply various gas, aerosol and liquid forms of pills for medicine, and to actively influence the posterior segment of the eye. It is possible to use IZ according to the proposed method for treating the anterior, middle and posterior segment of the eye. It is possible to use infrasound with a chamber filled with gas mixtures, aerosol, and ionized air. The duration of treatment when applying the proposed method of treatment is reduced on average by a week compared with the known method. Clinical trials of the proposed method have shown its high efficacy in various diseases of the eye, in particular in inflammatory diseases of the eyelids, anterior segment of the eye, iritis, keratitis, glaucoma, diseases of the optic nerve, hornoidea, the retina.

Claims (1)

METHOD FOR TREATING EYE DISEASES, which involves exposure to sound vibrations and drug therapy, characterized in that, in order to reduce treatment time, the eyeball and tissues of the orbit are affected by infrasonic vibrations with a frequency of 2-6 Hz, an intensity of 135-165 dB for 10-15 min course 10-15 days.