SU1051069A1 - Process for preparing sodium n-acetylalkylaminomethane sulfonates - Google Patents

Abstract

Aromas of the preparation of HATRIIHE1X SALTS N-Acetylalkylamino-methanolic acids of the general formula CH CO VJ (R) CH2 50 Nq, where C is alkyl with 17-20 carbon atoms, by condensation of the primary shkydamine with sodium oxymethanesulfonate in ary aseo in ary asero. that, in order to control the yield of the target product and simplify the process, the condensation is carried out at 4 ° -60 ° C using 2C) -40% excess of sodium oxymethanesulfone and 47-53% aqueous alcohol, followed directly by Botko reaction mass (L 5-6 kratnp excess of acetic angid chloride at 40-6OS.

Description

ABOUT)

; about izobrotsnne ref; ith; to the methods of obtaining sodium salts of N-acetylalkine aminomethylsulfonic acid of the general formulas СЬЦ (R) CH-jSO Na (1) where I am alknl with 17-2O atoms of uteroid having high surface-aggressive properties A nano-sulfonic acid of general form 1, which concludes that the primary alkylamine is condensed with sodium oxymethanesulfonate in a 4O-% aqueous aqueous &acetic anhydride in pyridine at 2G1 C, followed by heating at 1OO C, dilute the reaction mixture with nitrsmegane or acetone and filter the precipitate of the desired product with a yield of 47-6O% ij. The disadvantages of this method are the multistage process due to the need intermediate of alkylaminomethane sulfonate sodium, forming a hard-to-filter suspension that clogs the filter pores, low yield of the target product, use of toxin and expensive solvents (pyridine, nitromethane). The purpose of the invention is to simplify the process of obtaining N-acetylalkylamine methane sulfonago B, increase the yield of the target and expand the raw material base by using industrial high-pressure mixtures of aliphatic amines. This goal is achieved by haem, that according to the method of obtaining sodium salts of N-acetylene aminomethane sulfonic acids of general formula G, the condensation is carried out at 40 -6 ° C using 20-40% excess of sodium oxymethanesulfonate and 47-53% aqueous alcohol with subsequent directly by treating the reaction mass with a 5-6 fold excess of acetic anhydride at 40 ° -6 ° C. The desired product is isolated by distilling the solvent at a fluid pressure. The output of 80-90% (based on alkylamines). As a primary alklamine, it is possible to dissociate a fraction of the alkashams with 17–20 carbon atoms. The choice of the temperature interval (4O6O s) of the reaction is due, on the OOHAN 0692 side, to the viscosity of the reaction mass (thickening of which at temperature below 40 ° C makes it difficult to mix), and, on the other hand, thermal stability of intermediate products that are unstable when Example 1, A 3-necked flask equipped with a root stirrer and an industrial cooler is charged with 2OO ppm of 50% aqueous ethanol and 110 g of sodium oxymethanesulfonate. After the temperature has risen to 50 ° C and the solid phase dissolves into the flask 150 g of a pre-melted mixture of primary aliphatic amines of fraction C (- - is added. The reaction mass is stirred at 50 C 2-4. 280 ml of acetic ankhdrid are poured from the dropping funnel for 1.5 minutes and the reaction mass is maintained at 5 ° C and intensively transferred 3 h, after which the solvent is distilled off under a vacuum of a water-jet pump on a rotary evaporator. Inserted sodium acetylalkylamino methanesulfonate can be removed from methyl or ethyl alcohol. Yield 237 g (90% based on the amine mixture taken up). When using individual octadecylamine under the conditions of Example 1 and the same amounts of substances, N-acetyl-octadecylamine sodium tetanesulfonate is obtained in a yield of 92%. The product obtained in this way has the same surface-active properties as that obtained from the C – C 20 fraction amine amines. These doubles confirm the feasibility of using mixtures of aluminous mixtures to expand the raw material base. K (T1 (center of ethanol) must be maintained at 8 interval of 50+ 3%. The lower limit is limited by the solubility of sodium oxymethanesulfonate. P acetic anhydride). The read is minimal (a decrease leads to a lower yield), but it can be increased to sixfold. A further increase in the amount of acetic nhydride does not change the output of the product, an increase in the time of distillation is unreasonable for the unproductive plant. PRI and VI ep 2, To the parish 9O g of sodium xymethanesulfonate in 53%

310510604

the aqueous solution at 50 ° C was added and the solvent was distilled off under vacuum. Output

iSO g pre-molten mix- 3 1 g (88%),

si primary aliphatic amines frac-Tak image, the proposed method

Cn Cm-Cjg. The reaction mixture re-allows to simplify the techno-technology of mixing, at 55 C for 2 h, then in one day by eliminating the stages of separation

the addition was added with 34 O ml of acetic an condensation product and diluted with a reaction mixture, and the reaction mixture was stirred with a mass of solvent for 4 h, after which the target product was dissolved.

Claims (1)

METHOD FOR PRODUCING SODIUM SALTS OF N-APETHYLALKylAMINOMETHANE SULFOXID OF GENERAL FORMULA CH ^ CO S (R) CH ₂ 5O _T Mq, where R is alkyl with 17-20 carbon atoms, condensation of the primary alkylamine with sodium oximetansulfonate in aqueous alcohol, followed by acetylation with acetic anhydride when heated, characterized in that, in order to increase yield of the target product and simplification of the process, condensation is carried out at 40-60 ° C using a 20-40% excess of sodium oxymethanesulfonate and 47-53% aqueous alcohol, followed by direct processing of the reaction mass 5-6-fold excess of acetic anhydride *> Ryl at 40-60 ° С.