SU1045450A1 - Method of determining coagulation time - Google Patents

Method of determining coagulation time Download PDF

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Publication number
SU1045450A1
SU1045450A1 SU813345866A SU3345866A SU1045450A1 SU 1045450 A1 SU1045450 A1 SU 1045450A1 SU 813345866 A SU813345866 A SU 813345866A SU 3345866 A SU3345866 A SU 3345866A SU 1045450 A1 SU1045450 A1 SU 1045450A1
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SU
USSR - Soviet Union
Prior art keywords
blood
determining
time
kaolin
coagulation time
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Application number
SU813345866A
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Russian (ru)
Inventor
А.Ю. Холодов
Р.И. Лифшиц
А.А. Астахов
В.П. Воинов
Original Assignee
Kholodov A Yu
Lifshits R I
Astakhov A A
Voinov V P
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Application filed by Kholodov A Yu, Lifshits R I, Astakhov A A, Voinov V P filed Critical Kholodov A Yu
Priority to SU813345866A priority Critical patent/SU1045450A1/en
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Publication of SU1045450A1 publication Critical patent/SU1045450A1/en

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Abstract

СПОСОБ ОПРЕДЕЛЕНИЯ ВРЕЖНИ СВЕРТЫВАНИЯ КРОВИ путчем гжтивации свертывающей систеш крови каолином с последующим определением времени образовани  сгустков фибрина, о тличающий с  тем, что, с целью ускорени  и повышешш точности способа , цельную кровь добавл ют к сухому порошкообразному каолину в конечной концентрации 0,5fO,01%.METHOD FOR DETERMINING THE BLOOD COLLECTION OF THE BLOOD Patching the coagulation of the blood coagulation with kaolin followed by determining the time of formation of fibrin clots, which means that, in order to accelerate and improve the accuracy of the method, whole blood is added to the dry powder of kaolin at a final concentration of 0.5 ffos in the final concentration of 0.5 f i. %

Description

Изобретение относитс  к медихшне, . а именно к способам оцределени  биохимических параметров крови пациента во врем  оперативного вмешательства с искусственным кровообращением.This invention relates to copper,. in particular, methods for determining the biochemical parameters of a patient’s blood during surgery with artificial blood circulation.

Известен способ определени  времени свертывани  крови, преимущественно при операци х с искусственным кровообращением , при котором временно создают гипокоагул цию крови тепарином . В этом случае, воздейству  на цельную кровь .диатомной (инфузорной) земпей, определ ют активированное . врем  ее свертывани  и суд т о содержakии гепарина в крови по установленной мекду ними дл  данного пациента линейной зависимости.There is a known method for determining the blood coagulation time, mainly during operations with artificial blood circulation, at which blood is temporarily hypocoagulated with teparin. In this case, the effect on whole blood of the diatomic (infusorial) Zempei is determined to be activated. its clotting time is judged on the heparin content in the blood by the linear dependence established by them for the given patient.

Недостаток известного способа закпючаетс  в том, что при высоком со- ; держании гепарина в крови (пор дка 3-5 мг/кг массы пациента), необходимом so врем  искусственного кровообращени  , промежуток времени между началом и окончанием процесса образовани  фибринового сзтустка крови достаточно продолжителен и лишен четких границ. При проведении анализа с использованием диатомной земли, которую удаетс  смааать с цельной кровью в сосуде только цри многократном переворачивании его на 180° j надежно ре- -гистрируютс  шдаьсгустки в виде пленок и нитей фибрина, в процессе фор миро- .. вани  которых трудно выделить /начальную точку.The disadvantage of this method is that in case of high co-; keeping heparin in the blood (on the order of 3-5 mg / kg of the patient's mass), required for the time of cardiopulmonary bypass, the time interval between the beginning and the end of the process of formation of fibrinous blood by the blood is sufficiently long and lacks clear boundaries. When analyzing with the use of diatomaceous earth, which can be smeared with whole blood in a vessel, only if it is inverted by 180 ° j multiple times, it is reliably re-registered in the form of fibrin films and filaments, which are difficult to isolate during the formation of starting point.

Claims (1)

СПОСОБ ОПРЕДЕЛЕНИЯ ВРЕМЕНИ СВЕРТЫВАНИЯ КРОВИ путём активации свертывающей системы крови каолином с последующим определением времени образования сгустков фибрина, о тличающий ся тем, что, с целью ускорения и повышения точности способа, цельную кровь добавляют к сухому порошкообразному каолину в конечной концентрации 0,5f0,01%.METHOD FOR DETERMINING BLOOD COAGING TIME by activating the blood coagulation system with kaolin and then determining the time of formation of fibrin clots, characterized in that, in order to accelerate and improve the accuracy of the method, whole blood is added to dry powdery kaolin in a final concentration of 0.5f0.01% .
SU813345866A 1981-07-06 1981-07-06 Method of determining coagulation time SU1045450A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU813345866A SU1045450A1 (en) 1981-07-06 1981-07-06 Method of determining coagulation time

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU813345866A SU1045450A1 (en) 1981-07-06 1981-07-06 Method of determining coagulation time

Publications (1)

Publication Number Publication Date
SU1045450A1 true SU1045450A1 (en) 1991-02-07

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SU813345866A SU1045450A1 (en) 1981-07-06 1981-07-06 Method of determining coagulation time

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SU (1) SU1045450A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Дементьева И.И. Использование активированного времени свертывани дан контрол за уровнем гепаринизакии при операци х с искусственным кровообращением. - Анестезиологи и реанимаци , 1980, № 4, с. 29-3. Гольдберг Е.Д. , Драмарецка М.К. Характеристика функционального состо ни гемостаза здоровых взрослых людей. - Лаб. дело, 1978, № 10, с..589-590. s--irnnp llia SJ;jSv°JiW-:. :-йПМ1;:ШНШШ ..:-. It ikf- 1 ЕИА *

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