SK500402008U1 - Medicament for healing cold sores - Google Patents

Abstract

technical solution the concerns new healing preparation on the healing cold sores on the lips, the face and vaginal cold sores. Lie the vomiting agent is a formed uniform mixture 66.6 until 80 weight % of acetylsalicylic and to 100 weight Sheets % white grease and can further to contain and 3 until 3.6 weight % panthenol and / or 3 until 3.6 weight NYCHA % calcium

Description

Medicinal product for herpes healing

Technical field

The technical solution relates to a new medicament for the healing of cold sores on the lips, face and vaginal cold sores.

BACKGROUND OF THE INVENTION

Herpes is a skin disease caused by viruses. It has been known since the Greek civilization and is widespread throughout the world. Herpes simplex virus causes vaginal or vaginal herpes. In most cases, the first contact with the cold sore virus occurs as symptomatic either when infecting in childhood or by “getting” from another person. When the virus entered the tissue in the lips, it "commanded" the nerve cell DNA to produce cognate viruses. Herpes simplex mostly survives in nerve cells. Upon recovery, it travels along the nerve fibers and points to the skin surface. And it is at that time that itching appears to signal an impending health problem. After healing of the skin and mucous membranes, the virus “pulls” into the nerve roots and survives here in a quiet state. The outbreak of infection causes our body to create defensive antibodies, which in turn protect most people from the further development of herpes. As a rule, the cold sore will not appear throughout their lives. Some people, however, get the cold sore again. From a resting state in nerve cells, the virus "wakes up" - activated and travels - due to various provocation factors, back to the skin and mucous membranes, causing fresh cold sores. Known provoking moments include feverish diseases, excessive sunbathing, some foods and drinks, stressful situations, lack of sleep and rest, exhaustion and hormonal changes. These conditions are always related to the decline in immunity. There are four stages of each cold sore:

Stage 1 - itching, burning, skin tightness and pain are usually warning signs of approaching herpes.

Stage 2 - blister stage. On a slightly reddish skin a small group of small, rapidly expanding and merging blisters are poured. Their contents are clogged by the presence of a bacterial infection.

Stage 3 - the blisters gradually burst. Painful and oozing ulcers arise, which are covered with dried tissue wet, often with an admixture of blood.

- 2 4th stage - healing stage. The dried tissue fluid gradually peeled off and within 7-14 days the site healed completely without scars. Only a few days at the site of herpes can persist stained spot.

A drug that would permanently heal herpes and prevent its recurrence has not yet existed. Most people do not have major problems with herpes, and they need local treatment. Among the known natural herbal remedies that help in herpes are garlic, red wine, lysine-rich foods, vitamin C and zinc.

In some complicated cases, overall treatment with modern antiviral agents is performed. Cold sores are most commonly treated with aciclovir. Dermatologic, a virostatic under the trade name Zovirax, is commonly used as a medicine for cold sores on the lips and face. It is marketed in the form of an ointment that is applied to the affected area at the itching, burning or blistering stage and speeds up treatment. Vitamin B (B complex) is applied to promote healing. Its active ingredient contains the antiviral component aciclovir (aciclovir) 5% in a smooth white cream containing dimethicone (dimeticone), propylene glycol (propylene glycol), poloxamer (poloxamerum) 407, cetyl alcohol and searyl alcohol (alcohol cetylstearylicus), sodium lauryl sulphate, sodium lauryl sulphate. (vaselinum album), liquid paraffin (liquid paraffin) and purified water (aqua purificata). However, this medicinal product must not be used in patients who are hypersensitive to any of its ingredients. It is also not suitable for people with a weakened immune system and may cause mild burning, swelling and an undesirable allergic skin reaction after administration.

Furthermore, a virostatic with the trade name DUVIRA gel is commonly used as a medicament to treat cold sores on the lips and face. It is marketed in the form of an ointment that is applied to the affected area at the itching, burning or blistering stage and speeds up treatment. Its active ingredient contains dihydroxypropyladenine (dihydroxypropyladenine) in the gel and excipients carbomer (carbomerum) 940, glycerol (glycerol), methylparaben (methylparabenum) and purified water (aqua purificata). The disadvantage of this drug is that it is suitable for the treatment of herpes only in its initial phase. Such a drug often causes mild burning in patients and must not be used by patients with hypersensitivity to any of its ingredients.

Also used to treat cold sores on the lips and face is commonly used as a medicine phytopharmaceutical, dermatological, antiviral with the trade name LAKINAL gel. It is marketed in the form of an ointment that is applied to the affected area at the itching, burning or blistering stage and speeds up treatment. Its active ingredient contains a thick extract of lemon balm (salviae tinctura) in the gel and the excipients carbomer (carbomerum) 980, trolamine (trolaminum),

- 3 propylene glycol (propylene glycol), ethanol 96% (aethanol 96% pur subtillis), neo-purcelline (neo-PCL wasserloeslich), sodium edetate (sodium edetas) and purified water (aqua purificata). The medicinal product must not be used with known hypersensitivity to the active substance or to any of the excipients. Such a drug often causes local redness of the skin, itching and blisters in patients.

A common disadvantage of the herpes healing medicaments is that they are expensive and that they are unsuitable for a wide range of patients because of their large amount of active and excipients. In addition, they often cause severe local allergies, which are manifested by severe itching and redness of the site. This will stop the cold sore but at the same time cause another unpleasant condition.

The medicinal product for herpes healing according to the utility model SK no. 4842 consisting of a uniform mixture of 32 to 66.5% by weight of acetylsalicylic acid and up to 100% by weight of white petrolatum (vaselinum album) and which may further comprise 0.1 to 2.5% by weight of panthenol (panthenol). However, this preparation requires a relatively long treatment time for herpes.

The essence of the technical solution

These drawbacks are largely eliminated by the herpes healing medication according to the invention, which comprises a uniform mixture of 66.6 to 80% by weight of acetylsalicylic acid and up to 100% by weight of white petrolatum (vaselinum album).

It is preferred that the herpes healing medicament further comprises 3 to 3.6% by weight of panthenol (panthenol) and / or 3 to 3.6% by weight of calcium (calcia).

The advantage of the new medicament according to the invention is that it is cheaper and more affordable for patients than the herpes medicines used so far and is particularly suitable for the rapid treatment of cold sores, facial and vaginal cold sores. expert approach to the patient to determine in particular its appropriate chemical composition from the scope set forth in the claims for protection of the present invention. At the same time, because of the small amount of active and excipients, such a medicament is suitable for the treatment of a wide range of patients.

- 4 Examples

Specific examples of the drug according to the invention consist of the following uniform mixture:

Example 1

- 66,6% by weight of acetylsalicylic acid, i. j. 10 crushed Acylpyrine tablets with acetylsalicylic acid 500 mg per tablet,

- 33.4% by weight of white petrolatum (vaselinum album); j. in an amount of about 2.5 g,

Example 2

73,3% by weight of acetylsalicylic acid,. j. 11 crushed tablets of Acylpyrin with acetylsalicylic acid 500 mg per tablet,

- 3.3% by weight of panthenol (panthenol), i. 250 mg panthenol (panthenol).

23.4% by weight of white petrolatum (vaselinum album), i. j. in an amount of about 1.75 g.

Example 3:

- 66,6% by weight of acetylsalicylic acid, i. j. 10 crushed Acylpyrine tablets with acetylsalicylic acid 500 mg per tablet,

- 3,35% by weight of panthenol (panthenol), m.p. j. 250 mg panthenol (panthenol).

- 3, 35% by weight of calcium; j. 250 mg calcium

26.7% by weight of white petrolatum (vaselinum album), i. j. in an amount of about 2 g.

Example 4

- 80% by weight of acetylsalicylic acid, i. j. 20 crushed tablets of Acylpyrin with acetylsalicylic acid 500 mg per tablet,

- 20% by weight of white petrolatum (vaselinum album), i. j. in an amount of 2.5 g.

It is also possible to provide other examples of the medicinal product according to the invention in the form of a uniform mixture of substances formed by a possible combination of the chemical composition within the ranges of the weight% of the protection claims. It is advantageous if the physician determines on the prescription, according to the individual professional approach to the patient, the particular chemical composition of the herpes healing medicinal product within the scope of the chemical composition stated in the claims for protection of this technical solution.

In the case of cold sores on the lips, face avaginally, the medicament according to the invention is used in the form of an ointment, which is normally applied (applied) to the affected area at the stage of itching, burning or blistering. The proven efficacy of curing patients with a medicinal product according to the invention reaches up to 90%. The medicinal product must not be used if the patient is hypersensitive to any of its components.

- 1 Tu /

Claims (2)

PROTECTION REQUIREMENTS 1. A herpes healing medicinal product, characterized in that it comprises a uniform mixture of 66.6 to 80% by weight of acetylsalicylic acid and up to 100% by weight of white petrolatum. The herpes healing medicinal product according to claim 1, characterized in that it further comprises 3 to 3.6% by weight of panthenol and / or 3 to 3.6% by weight of calcium.