SK10472003A3 - Zvýšený výťažok aktívnych proteínov - Google Patents
Zvýšený výťažok aktívnych proteínov Download PDFInfo
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- SK10472003A3 SK10472003A3 SK1047-2003A SK10472003A SK10472003A3 SK 10472003 A3 SK10472003 A3 SK 10472003A3 SK 10472003 A SK10472003 A SK 10472003A SK 10472003 A3 SK10472003 A3 SK 10472003A3
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- protein
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- recombinant protein
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Measurement Of Radiation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27103301P | 2001-02-23 | 2001-02-23 | |
| PCT/US2002/005645 WO2002068455A2 (en) | 2001-02-23 | 2002-02-22 | Efficient recovery of correctly refolded proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK10472003A3 true SK10472003A3 (sk) | 2004-03-02 |
Family
ID=23033913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| SK1047-2003A SK10472003A3 (sk) | 2001-02-23 | 2002-02-22 | Zvýšený výťažok aktívnych proteínov |
Country Status (21)
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| US (2) | US7157557B2 (zh) |
| EP (1) | EP1366062B1 (zh) |
| JP (1) | JP2005505494A (zh) |
| KR (1) | KR20040052481A (zh) |
| CN (1) | CN1547586A (zh) |
| AT (1) | ATE517909T1 (zh) |
| AU (1) | AU2002255600B2 (zh) |
| BG (1) | BG108087A (zh) |
| CA (1) | CA2438094C (zh) |
| CZ (1) | CZ20032208A3 (zh) |
| EE (1) | EE200300408A (zh) |
| ES (1) | ES2370235T3 (zh) |
| HK (1) | HK1059267A1 (zh) |
| HU (1) | HUP0303246A2 (zh) |
| IL (1) | IL157446A0 (zh) |
| MX (1) | MXPA03007563A (zh) |
| PL (1) | PL374045A1 (zh) |
| RU (1) | RU2316563C2 (zh) |
| SK (1) | SK10472003A3 (zh) |
| WO (1) | WO2002068455A2 (zh) |
| ZA (1) | ZA200305909B (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL374045A1 (en) * | 2001-02-23 | 2005-09-19 | Immunex Corporation | Efficient recovery of correctly refolded proteins |
| PL2520654T3 (pl) | 2003-08-26 | 2017-08-31 | The Regents Of The University Of Colorado, A Body Corporate | Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych |
| SG156672A1 (en) * | 2004-10-22 | 2009-11-26 | Amgen Inc | Methods for refolding of recombinant antibodies |
| CA2584137A1 (en) * | 2004-10-22 | 2006-06-08 | Amgen Inc. | Methods for refolding polypeptides |
| WO2006079176A1 (en) * | 2005-01-28 | 2006-08-03 | Apollo Life Sciences Limited | Molecules and chimeric molecules thereof |
| CA2607663C (en) | 2005-05-19 | 2014-08-12 | Amgen Inc. | Compositions and methods for increasing the stability of antibodies |
| BRPI0611901A2 (pt) | 2005-06-14 | 2012-08-28 | Amgen, Inc | composição, liofilizado, kit, e, processo para preparar uma composição |
| EP1893632B1 (en) | 2005-06-17 | 2015-08-12 | Novo Nordisk Health Care AG | Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine |
| BRPI0621124A2 (pt) | 2005-12-22 | 2011-11-29 | Genentech Inc | métodos para recuperação de uma proteìna de ligação à heparina |
| WO2007102946A2 (en) | 2006-01-23 | 2007-09-13 | Amgen Inc. | Crystalline polypeptides |
| WO2008008975A2 (en) | 2006-07-14 | 2008-01-17 | Genentech, Inc. | Refolding of recombinant proteins |
| EP2094247B1 (en) | 2006-10-20 | 2022-06-29 | Amgen Inc. | Stable polypeptide formulations |
| KR101643514B1 (ko) | 2007-07-09 | 2016-07-27 | 제넨테크, 인크. | 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지 |
| MX2010002683A (es) * | 2007-09-14 | 2010-03-26 | Amgen Inc | Poblaciones de anticuerpos homogeneos. |
| JP5808323B2 (ja) | 2009-06-22 | 2015-11-10 | アムジエン・インコーポレーテツド | 化学的に制御されたレドックス状態を用いたタンパク質のリフォールディング |
| EP2445924B2 (en) | 2009-06-25 | 2023-12-13 | Amgen Inc. | Capture purification processes for proteins expressed in a non-mammalian system |
| WO2011041721A1 (en) | 2009-10-02 | 2011-04-07 | Biogen Idec Ma Inc. | Methods of preventing and removing trisulfide bonds |
| BR112012013330A2 (pt) * | 2009-12-02 | 2017-03-28 | Acceleron Pharma Inc | composições e métodos para aumentar meia vida do soro de proteínas de fusão fc |
| CN105288589A (zh) | 2011-02-07 | 2016-02-03 | 塞勒尼斯医疗控股公司 | 脂蛋白复合物及其制备和用途 |
| US8883982B2 (en) | 2011-06-08 | 2014-11-11 | Acceleron Pharma, Inc. | Compositions and methods for increasing serum half-life |
| CA2839917A1 (en) | 2011-06-24 | 2012-12-27 | The Regents Of The University Of Colorado, A Body Corporate | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
| KR20140137347A (ko) | 2012-01-10 | 2014-12-02 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 알파-1 안티트립신 융합 분자용 조성물, 방법 및 용도 |
| US9353165B2 (en) * | 2012-07-25 | 2016-05-31 | Grifols, S.A. | Purification of cell culture derived alpha1 protease inhibitor |
| CA2876099A1 (en) | 2012-08-02 | 2014-02-06 | F. Hoffmann-La Roche Ag | Method for producing monomeric and multimeric molecules and uses thereof |
| CN104902914B (zh) | 2012-09-11 | 2019-01-01 | 科荣生生物科学公司 | 高纯度和优异产量的正确折叠的依那西普 |
| SG11201506775VA (en) | 2013-03-08 | 2015-09-29 | Genzyme Corp | Continuous purification of therapeutic proteins |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI709570B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析法及製法 |
| AR103172A1 (es) * | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
| AU2017345490B2 (en) | 2016-10-21 | 2022-07-07 | Amgen Inc. | Pharmaceutical formulations and methods of making the same |
| AU2019332764A1 (en) | 2018-08-31 | 2021-05-06 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
| CA3114802A1 (en) | 2018-10-11 | 2020-04-16 | Amgen Inc. | Downstream processing of bispecific antibody constructs |
| WO2022140389A1 (en) | 2020-12-22 | 2022-06-30 | Amgen Inc. | Cell culture method |
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| US5453363A (en) * | 1985-10-23 | 1995-09-26 | Boehringer Mannheim Gmbh | Process for the activation of t-PA or Ing after genetic expression in prokaryotes |
| US4766205A (en) * | 1985-11-13 | 1988-08-23 | Beatrice Companies, Inc. | Method for isolation of recombinant polypeptides in biologically active forms |
| EP0293785A3 (en) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Cloning and expression of simian transforming growth factor-ss1 |
| US4970067A (en) * | 1988-12-12 | 1990-11-13 | Helene Curtis, Inc. | Method and composition to condition hair and impart semi-permanent hair set retention properties |
| GB8927546D0 (en) | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| AU648214B2 (en) | 1991-12-31 | 1994-04-14 | Lucky Limited | Recombinant gene coding for human alpha interferon and expression vector thereof, etc. |
| US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| CN1113389A (zh) * | 1993-08-04 | 1995-12-13 | 西巴-盖尔基股份公司 | 高分子量的脱硫水蛭素 |
| US6310185B1 (en) * | 1994-03-08 | 2001-10-30 | Memorial Sloan Kettering Cancer Center | Recombinant human anti-Lewis Y antibodies |
| WO1995032216A1 (en) | 1994-05-25 | 1995-11-30 | University Of Nebraska Board Of Regents | Biologically active glycoprotein hormones produced in procaryotic cells |
| BR9508419A (pt) * | 1994-07-22 | 1997-11-18 | Hoffmann La Roche | Composições farmacêuticas compreendendo uma proteina de ligação de tnf quinerica |
| US5879673A (en) * | 1996-01-25 | 1999-03-09 | Genentech, Inc. | Administration of thrombopoietin on a single day only |
| US5935824A (en) * | 1996-01-31 | 1999-08-10 | Technologene, Inc. | Protein expression system |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| FR2803303B1 (fr) | 2000-01-04 | 2002-05-10 | Aventis Pasteur | Glycoproteine d'enveloppe du vih modifiee chimiquement |
| PL374045A1 (en) * | 2001-02-23 | 2005-09-19 | Immunex Corporation | Efficient recovery of correctly refolded proteins |
-
2002
- 2002-02-22 PL PL02374045A patent/PL374045A1/xx unknown
- 2002-02-22 AU AU2002255600A patent/AU2002255600B2/en not_active Expired
- 2002-02-22 CA CA2438094A patent/CA2438094C/en not_active Expired - Fee Related
- 2002-02-22 ES ES02725004T patent/ES2370235T3/es not_active Expired - Lifetime
- 2002-02-22 MX MXPA03007563A patent/MXPA03007563A/es active IP Right Grant
- 2002-02-22 CZ CZ20032208A patent/CZ20032208A3/cs unknown
- 2002-02-22 CN CNA02805444XA patent/CN1547586A/zh active Pending
- 2002-02-22 WO PCT/US2002/005645 patent/WO2002068455A2/en active Application Filing
- 2002-02-22 RU RU2003127830/13A patent/RU2316563C2/ru active
- 2002-02-22 JP JP2002567965A patent/JP2005505494A/ja active Pending
- 2002-02-22 IL IL15744602A patent/IL157446A0/xx unknown
- 2002-02-22 EE EEP200300408A patent/EE200300408A/xx unknown
- 2002-02-22 AT AT02725004T patent/ATE517909T1/de not_active IP Right Cessation
- 2002-02-22 EP EP02725004A patent/EP1366062B1/en not_active Expired - Lifetime
- 2002-02-22 HU HU0303246A patent/HUP0303246A2/hu unknown
- 2002-02-22 KR KR10-2003-7010687A patent/KR20040052481A/ko not_active Application Discontinuation
- 2002-02-22 SK SK1047-2003A patent/SK10472003A3/sk not_active Application Discontinuation
- 2002-02-22 US US10/080,471 patent/US7157557B2/en not_active Expired - Lifetime
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- 2003-07-31 ZA ZA200305909A patent/ZA200305909B/en unknown
- 2003-08-13 BG BG108087A patent/BG108087A/bg unknown
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2004
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2006
- 2006-11-22 US US11/603,544 patent/US7544784B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IL157446A0 (en) | 2004-03-28 |
| EP1366062A2 (en) | 2003-12-03 |
| EE200300408A (et) | 2003-12-15 |
| MXPA03007563A (es) | 2003-12-11 |
| CA2438094C (en) | 2011-10-11 |
| PL374045A1 (en) | 2005-09-19 |
| HUP0303246A2 (hu) | 2003-12-29 |
| KR20040052481A (ko) | 2004-06-23 |
| US7544784B2 (en) | 2009-06-09 |
| CA2438094A1 (en) | 2002-09-06 |
| JP2005505494A (ja) | 2005-02-24 |
| AU2002255600B2 (en) | 2008-01-24 |
| CN1547586A (zh) | 2004-11-17 |
| CZ20032208A3 (cs) | 2004-01-14 |
| US20070270577A1 (en) | 2007-11-22 |
| US20020182665A1 (en) | 2002-12-05 |
| WO2002068455A3 (en) | 2003-09-18 |
| RU2316563C2 (ru) | 2008-02-10 |
| WO2002068455A2 (en) | 2002-09-06 |
| EP1366062B1 (en) | 2011-07-27 |
| HK1059267A1 (en) | 2004-06-25 |
| BG108087A (bg) | 2005-04-30 |
| ATE517909T1 (de) | 2011-08-15 |
| US7157557B2 (en) | 2007-01-02 |
| ZA200305909B (en) | 2004-06-04 |
| RU2003127830A (ru) | 2005-04-10 |
| ES2370235T3 (es) | 2011-12-13 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FC9A | Refused patent application |