SI4229056T1 - Triazolopiridinilne spojine kot inhibitorji kinaze - Google Patents
Triazolopiridinilne spojine kot inhibitorji kinazeInfo
- Publication number
- SI4229056T1 SI4229056T1 SI202130138T SI202130138T SI4229056T1 SI 4229056 T1 SI4229056 T1 SI 4229056T1 SI 202130138 T SI202130138 T SI 202130138T SI 202130138 T SI202130138 T SI 202130138T SI 4229056 T1 SI4229056 T1 SI 4229056T1
- Authority
- SI
- Slovenia
- Prior art keywords
- triazolopyridinyl
- compounds
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063093463P | 2020-10-19 | 2020-10-19 | |
| PCT/US2021/055340 WO2022086828A1 (en) | 2020-10-19 | 2021-10-18 | Triazolopyridinyl compounds as kinase inhibitors |
| EP21805787.5A EP4229056B1 (en) | 2020-10-19 | 2021-10-18 | Triazolopyridinyl compounds as kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI4229056T1 true SI4229056T1 (sl) | 2024-06-28 |
Family
ID=78536657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI202130138T SI4229056T1 (sl) | 2020-10-19 | 2021-10-18 | Triazolopiridinilne spojine kot inhibitorji kinaze |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US11767322B2 (sl) |
| EP (2) | EP4229056B1 (sl) |
| JP (1) | JP2023546166A (sl) |
| KR (1) | KR20230092960A (sl) |
| CN (1) | CN116802181A (sl) |
| AR (1) | AR123793A1 (sl) |
| AU (1) | AU2021364302A1 (sl) |
| CA (1) | CA3196059A1 (sl) |
| CL (1) | CL2023001123A1 (sl) |
| CO (1) | CO2023004926A2 (sl) |
| DK (1) | DK4229056T3 (sl) |
| FI (1) | FI4229056T3 (sl) |
| HR (1) | HRP20240739T1 (sl) |
| IL (1) | IL302113A (sl) |
| LT (1) | LT4229056T (sl) |
| MX (1) | MX2023004492A (sl) |
| PE (1) | PE20240219A1 (sl) |
| PL (1) | PL4229056T3 (sl) |
| PT (1) | PT4229056T (sl) |
| RS (1) | RS65620B1 (sl) |
| SI (1) | SI4229056T1 (sl) |
| TW (1) | TW202233614A (sl) |
| WO (1) | WO2022086828A1 (sl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20212000T1 (hr) * | 2017-02-13 | 2022-04-01 | Bristol-Myers Squibb Company | Aminotriazolopiridini kao inhibitori kinaze |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070191395A1 (en) | 2004-02-16 | 2007-08-16 | Katsuhiro Kawakami | Heterocyclic compounds having antifungal activity |
| WO2006004702A1 (en) | 2004-06-25 | 2006-01-12 | Amgen Inc. | Condensed triazoles and indazoles useful in treating citokines mediated diseases and other diseases |
| ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
| EP2277881A4 (en) | 2008-04-18 | 2011-09-07 | Shionogi & Co | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K |
| WO2010007100A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Ltd | 7-substituted amino triazoles as pi3k inhibitors |
| WO2010007099A1 (en) | 2008-07-15 | 2010-01-21 | Cellzome Limited | 2-aminoimidazo[1,2-b]pyridazine derivatives as pi3k inhibitors |
| WO2010057877A1 (en) | 2008-11-18 | 2010-05-27 | Cellzome Limited | 7-pyridinyl- or phenyl- substituted triazolo [1, 5 -a] pyridines as pi3k inhibitors |
| EP2393813B1 (en) | 2009-02-04 | 2013-07-31 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11 ß-hydroxysteroid dehydrogenase 1 useful for the treatment of diseases related to elevated level of cortisol |
| EP2897949B1 (en) | 2012-09-18 | 2018-01-10 | Bristol-Myers Squibb Company | Iap antagonists |
| BR112015030774A2 (pt) | 2013-06-10 | 2017-07-25 | Bayer Pharma AG | novos compostos para o tratamento de câncer |
| CN106573006A (zh) | 2014-08-21 | 2017-04-19 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为药物的rip1激酶抑制剂杂环酰胺 |
| US10023576B2 (en) | 2014-10-22 | 2018-07-17 | Bristol-Myers Squibb Company | Heteroaryl substituted pyrrolotriazine amine compounds as PI3K inhibitors |
| US10214537B2 (en) | 2014-10-22 | 2019-02-26 | Bristol-Myers Squibb Company | Bicyclic heteroaryl amine compounds |
| WO2017077968A1 (ja) | 2015-11-05 | 2017-05-11 | 住友化学株式会社 | 縮合複素環化合物 |
| WO2018017435A1 (en) | 2016-07-22 | 2018-01-25 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof |
| WO2018139436A1 (ja) | 2017-01-24 | 2018-08-02 | 住友化学株式会社 | 縮合複素環化合物及びそれを含有する組成物 |
| HRP20212000T1 (hr) | 2017-02-13 | 2022-04-01 | Bristol-Myers Squibb Company | Aminotriazolopiridini kao inhibitori kinaze |
| WO2018237370A1 (en) | 2017-06-23 | 2018-12-27 | Accro Bioscience Inc. | HETEROARYL COMPOUNDS AS INHIBITORS OF THE NECROSIS, COMPOSITION AND METHOD OF USE THEREOF |
| WO2019089442A1 (en) * | 2017-10-30 | 2019-05-09 | Bristol-Myers Squibb Company | Aminoimidazopyridines as kinase inhibitors |
| WO2019147782A1 (en) | 2018-01-26 | 2019-08-01 | Bristol-Myers Squibb Company | Aminopyrrolotriazines as kinase inhibitors |
| ES2945220T3 (es) | 2018-09-13 | 2023-06-29 | Bristol Myers Squibb Co | Indazol carboxamidas como inhibidores de cinasas |
| CN112673000B (zh) | 2018-09-13 | 2024-10-18 | 百时美施贵宝公司 | 作为受体相互作用蛋白激酶1抑制剂(ripk1)的1h-吲唑甲酰胺 |
| US20230391768A2 (en) | 2018-11-07 | 2023-12-07 | Dana-Farber Cancer Institute, Inc. | Imidazopyridine derivatives and aza-imidazopyridine derivatives as janus kinase 2 inhibitors and uses thereof |
| JP7323637B2 (ja) | 2019-03-22 | 2023-08-08 | ▲勁▼方医▲薬▼科技（上海）有限公司 | 置換複素環式アミド化合物、その調製方法、及びその医薬的使用 |
| US20220380355A1 (en) | 2019-10-03 | 2022-12-01 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| CN114230565B (zh) | 2020-09-09 | 2023-10-27 | 成都奥睿药业有限公司 | 5-取代吲哚3-酰胺衍生物及其制备方法和用途 |
| AR123793A1 (es) * | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
-
2021
- 2021-10-14 AR ARP210102843A patent/AR123793A1/es unknown
- 2021-10-18 HR HRP20240739TT patent/HRP20240739T1/hr unknown
- 2021-10-18 AU AU2021364302A patent/AU2021364302A1/en active Pending
- 2021-10-18 PL PL21805787.5T patent/PL4229056T3/pl unknown
- 2021-10-18 US US17/503,516 patent/US11767322B2/en active Active
- 2021-10-18 EP EP21805787.5A patent/EP4229056B1/en active Active
- 2021-10-18 PT PT218057875T patent/PT4229056T/pt unknown
- 2021-10-18 LT LTEPPCT/US2021/055340T patent/LT4229056T/lt unknown
- 2021-10-18 TW TW110138596A patent/TW202233614A/zh unknown
- 2021-10-18 CA CA3196059A patent/CA3196059A1/en active Pending
- 2021-10-18 CN CN202180070933.6A patent/CN116802181A/zh active Pending
- 2021-10-18 JP JP2023523570A patent/JP2023546166A/ja active Pending
- 2021-10-18 FI FIEP21805787.5T patent/FI4229056T3/fi active
- 2021-10-18 PE PE2023001446A patent/PE20240219A1/es unknown
- 2021-10-18 RS RS20240656A patent/RS65620B1/sr unknown
- 2021-10-18 WO PCT/US2021/055340 patent/WO2022086828A1/en active Application Filing
- 2021-10-18 IL IL302113A patent/IL302113A/en unknown
- 2021-10-18 SI SI202130138T patent/SI4229056T1/sl unknown
- 2021-10-18 DK DK21805787.5T patent/DK4229056T3/da active
- 2021-10-18 EP EP24159615.4A patent/EP4364737A3/en active Pending
- 2021-10-18 KR KR1020237016535A patent/KR20230092960A/ko active Search and Examination
- 2021-10-18 MX MX2023004492A patent/MX2023004492A/es unknown
-
2023
- 2023-04-18 CL CL2023001123A patent/CL2023001123A1/es unknown
- 2023-04-19 CO CONC2023/0004926A patent/CO2023004926A2/es unknown
- 2023-07-06 US US18/347,703 patent/US12110290B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP4229056A1 (en) | 2023-08-23 |
| EP4364737A3 (en) | 2024-08-07 |
| US20240109888A1 (en) | 2024-04-04 |
| US11767322B2 (en) | 2023-09-26 |
| JP2023546166A (ja) | 2023-11-01 |
| TW202233614A (zh) | 2022-09-01 |
| US12110290B2 (en) | 2024-10-08 |
| AU2021364302A1 (en) | 2023-06-22 |
| HRP20240739T1 (hr) | 2024-08-30 |
| CO2023004926A2 (es) | 2023-05-08 |
| PE20240219A1 (es) | 2024-02-16 |
| DK4229056T3 (da) | 2024-07-15 |
| KR20230092960A (ko) | 2023-06-26 |
| WO2022086828A1 (en) | 2022-04-28 |
| FI4229056T3 (fi) | 2024-06-18 |
| CL2023001123A1 (es) | 2023-09-22 |
| PT4229056T (pt) | 2024-05-21 |
| AU2021364302A9 (en) | 2024-05-02 |
| US20220119388A1 (en) | 2022-04-21 |
| CA3196059A1 (en) | 2022-04-28 |
| IL302113A (en) | 2023-06-01 |
| RS65620B1 (sr) | 2024-07-31 |
| EP4229056B1 (en) | 2024-04-10 |
| LT4229056T (lt) | 2024-06-10 |
| CN116802181A (zh) | 2023-09-22 |
| EP4364737A2 (en) | 2024-05-08 |
| AR123793A1 (es) | 2023-01-11 |
| MX2023004492A (es) | 2023-05-10 |
| PL4229056T3 (pl) | 2024-06-10 |
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