SI2950795T1 - Postopek za tretiranje in zdravljenje leishmanioze z uporabo feksinidazola - Google Patents
Postopek za tretiranje in zdravljenje leishmanioze z uporabo feksinidazola Download PDFInfo
- Publication number
- SI2950795T1 SI2950795T1 SI201430743T SI201430743T SI2950795T1 SI 2950795 T1 SI2950795 T1 SI 2950795T1 SI 201430743 T SI201430743 T SI 201430743T SI 201430743 T SI201430743 T SI 201430743T SI 2950795 T1 SI2950795 T1 SI 2950795T1
- Authority
- SI
- Slovenia
- Prior art keywords
- feksinidazole
- use according
- administered
- treating
- days
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (9)
- Postopek za tretiranje in zdravljenje leishmanioze z uporabo feksinidazola Patentni zahtevki1. Feskinidazol za uporabo v zdravljenju infekcije z Leishmania infantum pri psu, kjer pes vsaj trideset dni po zdravljenju s feksinidazolom nima relapsa.
- 2. Feksinidazol za uporabo po zahtevku 1, kjer je količina dajanega feksinidazola dovoljšna, da proizvede plazemsko koncentracijo feksinidazola, ki presega 10 ng/mL vsaj 1 uro tekom vsakega dneva v teku dajanja feksinidazola.
- 3. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer je količina dajanega feksinidazola dovoljšna, da proizvede plazemsko koncentracijo feksinidazola, ki presega 30 ng/mL vsaj 2 uri tekom vsakega dneva.
- 4. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer je količina dajanega feksinidazola dovoljšna, da proizvede plazemsko koncentracijo feksinidazola, kije večja od 60 ng/mL vsaj 1 krat tekom vsakega dneva.
- 5. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer se feksinidazol daje oralno v obdobju vsaj dvajset dni.
- 6. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer se feksinidazol daje vsaj osemindvajset dni.
- 7. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer je feksinidazol mikroniziran in suspendiran v raztopini vode in DMSO.
- 8. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer pes vsaj 180 dni po zdravljenju s feksinidazolom nima relapsa.
- 9. Feksinidazol za uporabo po katerem koli predhodnem zahtevku, kjer se feksinidazol metabolizira v feksinidazol sulfon in/ali feksinidazol sulfoksid.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361758918P | 2013-01-31 | 2013-01-31 | |
| EP14705908.3A EP2950795B1 (en) | 2013-01-31 | 2014-01-31 | Method for treating and curing leishmaniosis using fexinindazole |
| PCT/US2014/014134 WO2014121064A1 (en) | 2013-01-31 | 2014-01-31 | Method for treating and curing leishmaniosis using fexinindazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2950795T1 true SI2950795T1 (sl) | 2018-07-31 |
Family
ID=50151374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201430743T SI2950795T1 (sl) | 2013-01-31 | 2014-01-31 | Postopek za tretiranje in zdravljenje leishmanioze z uporabo feksinidazola |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9585871B2 (sl) |
| EP (1) | EP2950795B1 (sl) |
| AU (1) | AU2014212217B2 (sl) |
| CY (1) | CY1120381T1 (sl) |
| DK (1) | DK2950795T3 (sl) |
| ES (1) | ES2681420T3 (sl) |
| HK (1) | HK1211466A1 (sl) |
| HR (1) | HRP20181181T1 (sl) |
| HU (1) | HUE039467T2 (sl) |
| IL (1) | IL240246B (sl) |
| LT (1) | LT2950795T (sl) |
| MX (1) | MX367952B (sl) |
| PL (1) | PL2950795T3 (sl) |
| PT (1) | PT2950795T (sl) |
| RS (1) | RS57469B1 (sl) |
| SI (1) | SI2950795T1 (sl) |
| WO (1) | WO2014121064A1 (sl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3440062T (lt) * | 2016-04-06 | 2021-12-10 | Boehringer Ingelheim Animal Health USA Inc. | Enantiomeru praturtintų izoksazolino junginių - (s)-afoksolanerio kristalinio tolueno solvato gamybos būdas |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950360A (en) | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
| JPS4914624A (sl) | 1972-06-08 | 1974-02-08 | ||
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4134973A (en) | 1977-04-11 | 1979-01-16 | Merck & Co., Inc. | Carbohydrate derivatives of milbemycin and processes therefor |
| US4199569A (en) | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| US4144352A (en) | 1977-12-19 | 1979-03-13 | Merck & Co., Inc. | Milbemycin compounds as anthelmintic agents |
| US4203976A (en) | 1978-08-02 | 1980-05-20 | Merck & Co., Inc. | Sugar derivatives of C-076 compounds |
| JPS57139012A (en) | 1981-02-23 | 1982-08-27 | Sankyo Co Ltd | Anthelmintic composition |
| US4427663A (en) | 1982-03-16 | 1984-01-24 | Merck & Co., Inc. | 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof |
| EP0237482A1 (de) | 1986-03-06 | 1987-09-16 | Ciba-Geigy Ag | C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen |
| BR8701302A (pt) | 1986-03-25 | 1987-12-22 | Sankyo Co | Compostos macrolideos,sua preparacao e seu uso |
| EP0252879B1 (de) | 1986-07-02 | 1992-05-06 | Ciba-Geigy Ag | Pestizide |
| US4855317A (en) | 1987-03-06 | 1989-08-08 | Ciba-Geigy Corporation | Insecticides and parasiticides |
| US4871719A (en) | 1987-03-24 | 1989-10-03 | Ciba-Geigy Corporation | Composition for controlling parasites in productive livestock |
| US4874749A (en) | 1987-07-31 | 1989-10-17 | Merck & Co., Inc. | 4"-Deoxy-4-N-methylamino avermectin Bla/Blb |
| DE3888936T2 (de) | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
| NZ232422A (en) | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
| NZ247278A (en) | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
| US5345377A (en) | 1992-10-30 | 1994-09-06 | Electric Power Research Institute, Inc. | Harmonic controller for an active power line conditioner |
| GB9300883D0 (en) | 1993-01-18 | 1993-03-10 | Pfizer Ltd | Antiparasitic agents |
| AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
| US5885607A (en) | 1996-03-29 | 1999-03-23 | Rhone Merieux | N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs |
| FR2752525B1 (fr) | 1996-08-20 | 2000-05-05 | Rhone Merieux | Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede |
| US6010710A (en) | 1996-03-29 | 2000-01-04 | Merial | Direct pour-on skin solution for antiparasitic use in cattle and sheep |
| IE80657B1 (en) | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
| US6998131B2 (en) | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
| US6174540B1 (en) | 1998-09-14 | 2001-01-16 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated caster oil |
| CU23506B6 (es) | 2005-09-26 | 2010-04-13 | Ct Bioactivos Quimicos Univers | Composiciones farmacéuticas que contienen derivados nitrovinilfuránicos para el tratamiento de la leishmaniosis y la tripanosomosis |
| PT103503B (pt) | 2006-06-19 | 2009-05-18 | Univ Do Porto | Novos derivados do bisnaftalimidopropil, processo para a sua preparação, composições farmacêuticas que os contêm e sua utilização em doenças cancerígenas e parasitárias, nomeadamente leishmanioses, tripanossomíases e malária. |
| CA2656617C (en) | 2006-07-05 | 2014-10-14 | Aventis Agriculture | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof |
| DE112013000869T5 (de) | 2012-02-06 | 2014-10-16 | Merial Ltd. | Orale parasitizide Veterinärzusammensetzungen umfassend systemisch wirkende Wirkstoffe, Verfahren und Verwendun davon |
-
2014
- 2014-01-31 AU AU2014212217A patent/AU2014212217B2/en active Active
- 2014-01-31 US US14/169,713 patent/US9585871B2/en active Active
- 2014-01-31 DK DK14705908.3T patent/DK2950795T3/en active
- 2014-01-31 WO PCT/US2014/014134 patent/WO2014121064A1/en active Application Filing
- 2014-01-31 SI SI201430743T patent/SI2950795T1/sl unknown
- 2014-01-31 HU HUE14705908A patent/HUE039467T2/hu unknown
- 2014-01-31 ES ES14705908.3T patent/ES2681420T3/es active Active
- 2014-01-31 EP EP14705908.3A patent/EP2950795B1/en active Active
- 2014-01-31 RS RS20180840A patent/RS57469B1/sr unknown
- 2014-01-31 MX MX2015009907A patent/MX367952B/es active IP Right Grant
- 2014-01-31 LT LTEP14705908.3T patent/LT2950795T/lt unknown
- 2014-01-31 PT PT147059083T patent/PT2950795T/pt unknown
- 2014-01-31 PL PL14705908T patent/PL2950795T3/pl unknown
-
2015
- 2015-07-30 IL IL240246A patent/IL240246B/en active IP Right Grant
- 2015-12-11 HK HK15112231.7A patent/HK1211466A1/xx unknown
-
2018
- 2018-07-03 CY CY20181100687T patent/CY1120381T1/el unknown
- 2018-07-24 HR HRP20181181TT patent/HRP20181181T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9585871B2 (en) | 2017-03-07 |
| HUE039467T2 (hu) | 2019-01-28 |
| LT2950795T (lt) | 2018-06-25 |
| HK1211466A1 (en) | 2016-05-27 |
| DK2950795T3 (en) | 2018-07-30 |
| EP2950795A1 (en) | 2015-12-09 |
| WO2014121064A1 (en) | 2014-08-07 |
| IL240246A0 (en) | 2015-09-24 |
| HRP20181181T1 (hr) | 2018-10-19 |
| EP2950795B1 (en) | 2018-04-25 |
| AU2014212217A1 (en) | 2015-08-20 |
| PL2950795T3 (pl) | 2018-09-28 |
| MX2015009907A (es) | 2016-03-01 |
| IL240246B (en) | 2019-03-31 |
| ES2681420T3 (es) | 2018-09-13 |
| RS57469B1 (sr) | 2018-09-28 |
| US20140213624A1 (en) | 2014-07-31 |
| PT2950795T (pt) | 2018-07-30 |
| CY1120381T1 (el) | 2019-07-10 |
| MX367952B (es) | 2019-09-12 |
| AU2014212217B2 (en) | 2016-11-10 |
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| SI2950795T1 (sl) | Postopek za tretiranje in zdravljenje leishmanioze z uporabo feksinidazola |