SI2637709T1 - Vsadki za polnjenje nosilnih kosti, ki imajo hierarhično organizirano arhitekturo, ki izhaja iz preoblikovanja rastlinskih konstrukcij - Google Patents

Vsadki za polnjenje nosilnih kosti, ki imajo hierarhično organizirano arhitekturo, ki izhaja iz preoblikovanja rastlinskih konstrukcij

Info

Publication number
SI2637709T1
SI2637709T1 SI201130501T SI201130501T SI2637709T1 SI 2637709 T1 SI2637709 T1 SI 2637709T1 SI 201130501 T SI201130501 T SI 201130501T SI 201130501 T SI201130501 T SI 201130501T SI 2637709 T1 SI2637709 T1 SI 2637709T1
Authority
SI
Slovenia
Prior art keywords
implants
deriving
transformation
load bearing
bearing bone
Prior art date
Application number
SI201130501T
Other languages
English (en)
Inventor
Anna Tampieri
Simone Sprio
Andrea Ruffini
Julia Will
Peter Greil
Frank Muller
Fernandez Julian Martinez
Raya Carmen Torres
Feria Francisco Manuel Varela
Rico Joaquin Ramirez
Marie-Francoise Harmand
Original Assignee
Consiglio Nazionale Delle Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Delle Ricerche filed Critical Consiglio Nazionale Delle Ricerche
Publication of SI2637709T1 publication Critical patent/SI2637709T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/501Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/10Ceramics or glasses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Ceramic Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Cultivation Of Plants (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
SI201130501T 2010-11-08 2011-11-08 Vsadki za polnjenje nosilnih kosti, ki imajo hierarhično organizirano arhitekturo, ki izhaja iz preoblikovanja rastlinskih konstrukcij SI2637709T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT002070A ITMI20102070A1 (it) 2010-11-08 2010-11-08 Impianti per sostituzioni ossee "load bearing" ad architettura gerarchicamente organizzata derivante dalla trasformazione di strutture vegetali
PCT/IB2011/054980 WO2012063201A1 (en) 2010-11-08 2011-11-08 The present invention relates to a bone substitute comprising a core based on hydroxyapatite (ha), obtained from at least one porous wood, or based on collagen fibres and hydroxyapatite, and a shell, based on hydroxyapatite (ha) or silicon carbide (sic), obtained from at least one wood having a lower porosity than the at least one wood of the core. the porous wood has a total porosity of between 60% and 95%, preferably between 65% and 85%, and it is selected from amongst the choices of rattan, pine, abachi and balsa wood. the wood of the shell has a porosity of between 20% and 60%, preferably between 30% and 50%. the bone substitute is utilized for the substitution and regeneration of bone, preferably for bones subjected to mechanical loads, such as long bones of the leg and arm, preferably the tibia, metatarsus, femur, humerus or radius.
EP11794855.4A EP2637709B1 (en) 2010-11-08 2011-11-08 Implants for load bearing bone substitutions having hierarchical organized architecture deriving from transformation of vegetal structures

Publications (1)

Publication Number Publication Date
SI2637709T1 true SI2637709T1 (sl) 2015-08-31

Family

ID=43742685

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201130501T SI2637709T1 (sl) 2010-11-08 2011-11-08 Vsadki za polnjenje nosilnih kosti, ki imajo hierarhično organizirano arhitekturo, ki izhaja iz preoblikovanja rastlinskih konstrukcij

Country Status (16)

Country Link
US (1) US9326948B2 (sl)
EP (1) EP2637709B1 (sl)
CN (1) CN103702692B (sl)
AU (1) AU2011328893B2 (sl)
CA (1) CA2830483C (sl)
DK (1) DK2637709T3 (sl)
ES (1) ES2539703T3 (sl)
HK (1) HK1196786A1 (sl)
HU (1) HUE026305T2 (sl)
IT (1) ITMI20102070A1 (sl)
PL (1) PL2637709T3 (sl)
PT (1) PT2637709E (sl)
RU (1) RU2585958C2 (sl)
SI (1) SI2637709T1 (sl)
SM (1) SMT201500151B (sl)
WO (1) WO2012063201A1 (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010207472B2 (en) 2009-01-23 2015-05-21 Royal College Of Surgeons In Ireland Layered scaffold suitable for osteochondral repair
TWI517866B (zh) * 2012-11-05 2016-01-21 Far Eastern New Century Corp Porous bone filling material
CN103170011B (zh) * 2013-04-10 2014-06-18 浙江大学 一种生物陶瓷原位包覆的镁人工骨及其制备方法
CN103961742A (zh) * 2014-05-14 2014-08-06 常州大学 含有益离子的磷酸钙多孔支架的制备方法
US10290234B2 (en) * 2015-01-19 2019-05-14 Ammolite Biomodels Inc. Simulated bone materials and methods of making same
EP3590544B1 (en) 2015-08-06 2024-09-18 Greenbone Ortho S.p.A. Large 3d porous scaffolds made of active hydroxyapatite obtained by biomorphic transformation of natural structures and process for obtaining them
ITUB20152962A1 (it) * 2015-08-06 2017-02-06 Consiglio Nazionale Ricerche Grandi scaffold porosi in 3D realizzati in idrossiapatite attiva ottenuta tramite trasformazione biomorfica di strutture naturali
ITUB20152939A1 (it) * 2015-08-06 2017-02-06 Consiglio Nazionale Ricerche Processo per produrre grandi scaffold porosi in 3D realizzati in idrossiapatite attiva ottenuta tramite trasformazione biomorfica di strutture naturali?
CN105536072B (zh) * 2015-10-22 2018-06-12 上海纳米技术及应用国家工程研究中心有限公司 一种锶、铁掺杂羟基磷灰石胶原纤维复合支架材料及制备方法
KR101981704B1 (ko) * 2017-05-31 2019-05-24 한국생산기술연구원 동결 주조법을 이용한 다공성 세라믹 지지체 제조방법 및 이에 의해 제조된 다공성 세라믹 지지체
EP3735204B1 (en) 2018-01-02 2023-09-06 Cartiheal (2009) Ltd. Implantation tool for optimized solid substrates promoting cell and tissue growth
CN111249523B (zh) * 2020-03-10 2021-07-13 四川大学 仿骨复合材料支架及其制备方法
CN112402695B (zh) * 2020-11-27 2022-09-20 南方科技大学 一种取向结构的原位矿化仿生骨水凝胶复合材料及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5522894A (en) * 1984-12-14 1996-06-04 Draenert; Klaus Bone replacement material made of absorbable beads
IT1318663B1 (it) 2000-08-02 2003-08-27 Mediolanum Farmaceutici Srl Membrane di collagene a due facce di cui una organizzata a livellomacromolecolare.
ES2187371B1 (es) 2001-10-11 2004-09-16 Universidad De Sevilla Procedimiento para la fabricacion de ceramicas de carburo de silicio a partir de precursores vegetales.
ITMI20030186A1 (it) * 2003-02-05 2004-08-06 Consiglio Nazionale Ricerche Procedimento di sintesi di tessuto osseo artificiale,
EP1642599B1 (en) * 2003-05-26 2010-12-01 HOYA Corporation Porous composite containing calcium phosphate and process for producing the same
ITMI20050343A1 (it) 2005-03-04 2006-09-05 Fin Ceramica Faenza S R L Sostituto cartilagineo e osteocindrale comprendente una struttura multistrato e relativo impiego
ITMI20051966A1 (it) 2005-10-18 2007-04-19 C N R Consiglio Naz Delle Ri C Una idrossiapatite plurisostituita ed il relativo composito con un polimero naturale e-o sintetico loro preparazione e usi

Also Published As

Publication number Publication date
US20140134258A1 (en) 2014-05-15
CN103702692B (zh) 2015-11-25
EP2637709A1 (en) 2013-09-18
HUE026305T2 (en) 2016-06-28
RU2013127019A (ru) 2014-12-20
DK2637709T3 (en) 2015-07-13
AU2011328893B2 (en) 2016-04-14
ES2539703T3 (es) 2015-07-03
WO2012063201A8 (en) 2013-07-04
CA2830483A1 (en) 2012-05-18
SMT201500151B (it) 2015-09-07
WO2012063201A1 (en) 2012-05-18
CN103702692A (zh) 2014-04-02
RU2585958C2 (ru) 2016-06-10
HK1196786A1 (zh) 2014-12-24
AU2011328893A1 (en) 2013-07-04
PL2637709T3 (pl) 2015-10-30
US9326948B2 (en) 2016-05-03
PT2637709E (pt) 2015-07-28
EP2637709B1 (en) 2015-04-08
CA2830483C (en) 2019-04-02
ITMI20102070A1 (it) 2012-05-09

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