SI2256108T1 - Substituirani triazinski kinazni inhibitorji - Google Patents
Substituirani triazinski kinazni inhibitorjiInfo
- Publication number
- SI2256108T1 SI2256108T1 SI200332475A SI200332475A SI2256108T1 SI 2256108 T1 SI2256108 T1 SI 2256108T1 SI 200332475 A SI200332475 A SI 200332475A SI 200332475 A SI200332475 A SI 200332475A SI 2256108 T1 SI2256108 T1 SI 2256108T1
- Authority
- SI
- Slovenia
- Prior art keywords
- kinase inhibitors
- substituted triazine
- triazine kinase
- substituted
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39694802P | 2002-07-18 | 2002-07-18 | |
| EP10176670.7A EP2256108B1 (en) | 2002-07-18 | 2003-07-18 | Substituted triazine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2256108T1 true SI2256108T1 (sl) | 2016-05-31 |
Family
ID=30770960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200332475A SI2256108T1 (sl) | 2002-07-18 | 2003-07-18 | Substituirani triazinski kinazni inhibitorji |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7205298B2 (sl) |
| EP (2) | EP1546121B1 (sl) |
| AU (1) | AU2003259153A1 (sl) |
| CY (1) | CY1117951T1 (sl) |
| DK (1) | DK2256108T3 (sl) |
| ES (2) | ES2575522T3 (sl) |
| HU (1) | HUE029020T2 (sl) |
| SI (1) | SI2256108T1 (sl) |
| WO (1) | WO2004009562A1 (sl) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0307268D0 (en) | 2003-03-28 | 2003-05-07 | Syngenta Ltd | Organic compounds |
| US20050130968A1 (en) * | 2003-10-03 | 2005-06-16 | Irvine Nicholas M. | Fungicidal 4-(2-aminopyridin-4-yl)-N-phenyl-1,3,5-triazin-2-amine derivatives |
| CA2549869C (en) | 2003-12-18 | 2015-05-05 | Janssen Pharmaceutica N.V. | Pyrido- and pyrimidopyrimidine derivatives as anti- proliferative agents |
| AU2005245885B2 (en) | 2004-05-14 | 2011-01-20 | Vertex Pharmaceuticals, Incorporated | Pyrrole compounds as inhibitors of ERK protein kinase, synthesis thereof and intermediates thereto |
| NI200700147A (es) | 2004-12-08 | 2019-05-10 | Janssen Pharmaceutica Nv | Derivados de quinazolina inhibidores de cinasas dirigidos a multip |
| UA92608C2 (en) * | 2005-06-30 | 2010-11-25 | Янссен Фармацевтика Н.В. | Cyclic anilino - pyridinotriazines as gsk-3 inhibitors |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007274284B2 (en) | 2006-07-13 | 2012-04-26 | Janssen Pharmaceutica N.V. | Mtki quinazoline derivatives |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| ES2562218T3 (es) | 2007-07-27 | 2016-03-03 | Janssen Pharmaceutica, N.V. | Pirrolopirimidinas útiles para el tratamiento de enfermedades proliferativas |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US20120121515A1 (en) | 2009-03-13 | 2012-05-17 | Lenny Dang | Methods and compositions for cell-proliferation-related disorders |
| JP2012529512A (ja) * | 2009-06-08 | 2012-11-22 | アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー | トリアジン誘導体類及びそれらの治療応用 |
| TWI598337B (zh) | 2009-06-29 | 2017-09-11 | 阿吉歐斯製藥公司 | 治療化合物及組成物 |
| US8415381B2 (en) | 2009-07-30 | 2013-04-09 | Novartis Ag | Heteroaryl compounds and their uses |
| JP2013503934A (ja) | 2009-09-02 | 2013-02-04 | エルジー・ケム・リミテッド | 有機スズ化合物、その製造方法およびそれを用いたポリラクチドの製造方法 |
| EP3064595B1 (en) | 2009-10-21 | 2019-02-27 | Agios Pharmaceuticals, Inc. | Methods for cell-proliferation-related disorders |
| BR112013005889A2 (pt) | 2010-09-13 | 2020-08-25 | Novartis Ag | triazinaoxadiazóis, composição farmacêutica que os compreende e uso dos mesmos |
| WO2012066070A1 (en) * | 2010-11-17 | 2012-05-24 | Novartis Ag | 3-(aminoaryl)-pyridine compounds |
| JP2014506878A (ja) * | 2011-01-28 | 2014-03-20 | ノバルティス アーゲー | Ｃｄｋ９阻害剤としての置換ビ−ヘテロアリール化合物およびそれらの使用 |
| CA2826464C (en) * | 2011-03-02 | 2020-07-28 | Lead Discovery Center Gmbh | Pharmaceutically active disubstituted triazine derivatives |
| WO2012117059A1 (en) | 2011-03-02 | 2012-09-07 | Lead Discovery Center Gmbh | Pharmaceutically active disubstituted pyridine derivatives |
| MX2013012233A (es) | 2011-04-19 | 2014-01-23 | Bayer Pharma AG | 4-aril-n-fenil-1,3,5-triazin-2-aminas sustituidas. |
| KR101873543B1 (ko) | 2011-05-03 | 2018-07-02 | 아지오스 파마슈티컬스 아이엔씨. | 치료에 사용하기 위한 피루베이트 키나아제 활성제 |
| TWI555737B (zh) | 2011-05-24 | 2016-11-01 | 拜耳知識產權公司 | 含有硫醯亞胺基團之４－芳基－ｎ－苯基－１，３，５－三氮雜苯－２－胺 |
| EP2714048A4 (en) * | 2011-05-27 | 2014-11-05 | Univ Temple | SUBSTITUTED 2-BENZYLIDENE-2H-BENZO [B] [1,4] THIAZIN-3 (4H) -ONES, DERIVED THEREFROM, AND THEIR THERAPEUTIC USES |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN103930165B (zh) | 2011-09-02 | 2018-05-25 | 纽约市哥伦比亚大学理事会 | 用以治疗肥胖症的代谢紊乱的CaMKII、IP3R、钙调神经磷酸酶、P38和MK2/3抑制剂 |
| CA2848616A1 (en) | 2011-09-16 | 2013-03-21 | Bayer Intellectual Property Gmbh | Disubstituted 5-fluoro-pyrimidines |
| EP2755948B1 (en) | 2011-09-16 | 2016-05-25 | Bayer Intellectual Property GmbH | Disubstituted 5-fluoro pyrimidine derivatives containing a sulfoximine group |
| CA2854266A1 (en) | 2011-11-30 | 2013-06-06 | Actelion Pharmaceuticals Ltd | 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics |
| CN115521264A (zh) | 2012-01-06 | 2022-12-27 | 法国施维雅药厂 | 治疗活性化合物及其使用方法 |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| WO2014062511A1 (en) | 2012-10-15 | 2014-04-24 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| US20150259300A1 (en) | 2012-10-18 | 2015-09-17 | Bayer Pharma Aktiengesellschaft | 4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amines containing a sulfone group |
| CN104854091B (zh) | 2012-10-18 | 2018-04-03 | 拜耳药业股份公司 | 含砜基团的5‑氟‑n‑(吡啶‑2‑基)吡啶‑2‑胺衍生物 |
| TW201418243A (zh) | 2012-11-15 | 2014-05-16 | Bayer Pharma AG | 含有磺醯亞胺基團之ｎ－（吡啶－２－基）嘧啶－４－胺衍生物 |
| WO2014108832A1 (en) | 2013-01-09 | 2014-07-17 | Actelion Pharmaceuticals Ltd | Antibacterial oxazolone derivatives |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| CN105593215B (zh) | 2013-07-11 | 2019-01-15 | 安吉奥斯医药品有限公司 | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| EA032070B1 (ru) | 2013-07-11 | 2019-04-30 | Аджиос Фармасьютикалз, Инк. | Соединения n,6-бис(арил или гетероарил)-1,3,5-триазин-2,4-диамина в качестве ингибиторов мутантов idh2 для лечения ракового заболевания |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| SG10201709187TA (en) | 2013-08-02 | 2017-12-28 | Agios Pharmaceuticals Inc | Therapeutically active compounds and their methods of use |
| CA2925177A1 (en) * | 2013-09-20 | 2015-03-26 | Carna Biosciences, Inc. | Novel triazine derivative |
| KR20220070066A (ko) | 2014-03-14 | 2022-05-27 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| WO2016059011A1 (en) | 2014-10-16 | 2016-04-21 | Bayer Pharma Aktiengesellschaft | Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group |
| WO2016150902A1 (en) | 2015-03-24 | 2016-09-29 | Bayer Pharma Aktiengesellschaft | Use of 4-(4-fluoro-2-methoxyphenyl)-n-{3-[(s-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine for treating gastric cancers |
| JP2018509439A (ja) | 2015-03-24 | 2018-04-05 | バイエル ファーマ アクチエンゲゼルシャフト | 多発性骨髄腫を治療するための４−（４−フルオロ−２−メトキシフェニル）−ｎ−｛３−［（ｓ−メチルスルホンイミドイル）メチル］フェニル｝−１，３，５−トリアジン−２−アミンの使用 |
| WO2016150903A1 (en) | 2015-03-24 | 2016-09-29 | Bayer Pharma Aktiengesellschaft | Use of 4-(4-fluoro-2-methoxyphenyl)-n-{3-[(s-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine for treating lymphomas |
| MD3307271T2 (ro) | 2015-06-11 | 2024-01-31 | Agios Pharmaceuticals Inc | Metode de utilizare a activatorilor de piruvat kinază |
| CA2993615A1 (en) | 2015-08-05 | 2017-02-09 | Agios Pharmaceuticals, Inc. | Methods of preparing 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diols and 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diamines |
| EP3356373B1 (en) | 2015-09-29 | 2020-02-19 | Bayer Pharma Aktiengesellschaft | Novel macrocyclic sulfondiimine compounds |
| WO2017060167A1 (en) | 2015-10-08 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | Novel modified macrocyclic compounds |
| WO2017060322A2 (en) | 2015-10-10 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | Ptefb-inhibitor-adc |
| HRP20211790T1 (hr) | 2015-10-15 | 2022-03-04 | Les Laboratoires Servier | Kombinirana terapija za liječenje maligniteta |
| PL3362065T3 (pl) | 2015-10-15 | 2024-09-16 | Les Laboratoires Servier | Terapia skojarzona zawierająca iwosidenib, cytarabinę i daunorubicynę lub idarubicynę do leczenia ostrej białaczki szpikowej |
| WO2018177889A1 (en) | 2017-03-28 | 2018-10-04 | Bayer Aktiengesellschaft | Novel ptefb inhibiting macrocyclic compounds |
| PL3601253T3 (pl) | 2017-03-28 | 2022-01-17 | Bayer Aktiengesellschaft | Nowe hamujące ptefb związki makrocykliczne |
| JOP20200196A1 (ar) | 2018-02-13 | 2020-08-13 | Bayer Ag | استخدام 5-فلورو-4-(4-فلورو-2-مثوكسي فنيل)- n-{4-[(s-مثيل كبريتون ايميدويل) مثيل] بيريدين-2-يل} بيريدين -2-امين لمعالجة ليمفومة الخلايا البائية الكبيرة المنتشرة |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| CN109503473B (zh) * | 2019-01-07 | 2020-07-07 | 上海慧川生物医药科技有限公司 | 2-甲氧基-3-氨基-5-吡啶硼酸频哪醇酯及其中间体的合成方法 |
| CN110357863B (zh) * | 2019-08-27 | 2023-04-14 | 药雅科技(上海)有限公司 | 一种三嗪双芳香环衍生物表皮生长因子抑制剂及其制备方法与用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2452130A1 (en) | 1992-03-05 | 1993-09-16 | Francis J. Burrows | Methods and compositions for targeting the vasculature of solid tumors |
| US5474765A (en) | 1992-03-23 | 1995-12-12 | Ut Sw Medical Ctr At Dallas | Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells |
| US5902795A (en) | 1992-06-16 | 1999-05-11 | Trustees Of Tufts College | Oligosaccharides reactive with hyaluronan-binding protein and their methods of use |
| DE29624503U1 (de) | 1995-04-19 | 2004-09-16 | Boston Scientific Scimed, Inc. | Arzneimittel-freisetzender beschichteter Stent |
| CA2372053C (en) | 1999-04-28 | 2008-09-02 | Board Of Regents, The University Of Texas System | Compositions and methods for cancer treatment by selectively inhibiting vegf |
| ATE396978T1 (de) | 1999-10-07 | 2008-06-15 | Amgen Inc | Triazin-kinase-hemmer |
| US6776796B2 (en) | 2000-05-12 | 2004-08-17 | Cordis Corportation | Antiinflammatory drug and delivery device |
| JP3499808B2 (ja) | 2000-06-29 | 2004-02-23 | 本田技研工業株式会社 | 電子文書分類システム |
-
2003
- 2003-07-18 HU HUE10176670A patent/HUE029020T2/en unknown
- 2003-07-18 ES ES10176670.7T patent/ES2575522T3/es not_active Expired - Lifetime
- 2003-07-18 AU AU2003259153A patent/AU2003259153A1/en not_active Abandoned
- 2003-07-18 US US10/622,721 patent/US7205298B2/en not_active Expired - Lifetime
- 2003-07-18 EP EP03765676A patent/EP1546121B1/en not_active Expired - Lifetime
- 2003-07-18 WO PCT/US2003/022390 patent/WO2004009562A1/en not_active Application Discontinuation
- 2003-07-18 EP EP10176670.7A patent/EP2256108B1/en not_active Expired - Lifetime
- 2003-07-18 ES ES03765676T patent/ES2392426T3/es not_active Expired - Lifetime
- 2003-07-18 DK DK10176670.7T patent/DK2256108T3/en active
- 2003-07-18 SI SI200332475A patent/SI2256108T1/sl unknown
-
2016
- 2016-06-13 CY CY20161100515T patent/CY1117951T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1546121B1 (en) | 2012-08-29 |
| DK2256108T3 (en) | 2016-04-11 |
| CY1117951T1 (el) | 2017-05-17 |
| US7205298B2 (en) | 2007-04-17 |
| EP1546121A4 (en) | 2007-08-15 |
| WO2004009562A1 (en) | 2004-01-29 |
| US20040082581A1 (en) | 2004-04-29 |
| ES2392426T3 (es) | 2012-12-10 |
| EP2256108B1 (en) | 2016-03-23 |
| ES2575522T3 (es) | 2016-06-29 |
| AU2003259153A1 (en) | 2004-02-09 |
| EP1546121A1 (en) | 2005-06-29 |
| EP2256108A1 (en) | 2010-12-01 |
| HUE029020T2 (en) | 2017-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2256108T1 (sl) | Substituirani triazinski kinazni inhibitorji | |
| EP1496910A4 (en) | KINASE INHIBITORS | |
| SI1569907T1 (sl) | Na nikotinamidu osnovani kinazni inhibitorji | |
| AU2003271566A8 (en) | Pyrrolopyrazines as kinase inhibitors | |
| IL165515A0 (en) | Bisindolyl-maleimid derivatives as kinase inhibitors | |
| AU2003299651A8 (en) | Tyrosine kinase inhibitors | |
| EP1558609A4 (en) | KINASE INHIBITORS | |
| EP1543009A4 (en) | Pyrrolotriazine KINASE INHIBITORS | |
| EP1539763A4 (en) | Azaindole KINASE INHIBITORS | |
| IL173381A0 (en) | 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors | |
| AP2048A (en) | Diazepinoindole derivatives as kinase inhibitors | |
| AU2003249442A1 (en) | Kinase inhibitors | |
| AU2003298942A8 (en) | Tyrosine kinase inhibitors | |
| IL172132A0 (en) | Thienopyridone derivatives as kinase inhibitors | |
| AP2006003620A0 (en) | Imidazopyrazine tyroshine kinase inhibitors | |
| AU2003282891A8 (en) | Novel tyrosine kinases inhibitors | |
| EP1497019A4 (en) | USE AS KINASEINHIBITORS USEFUL PYRROLO-TRIAZIN-ANILINE COMPOUNDS | |
| IL173200A0 (en) | Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors | |
| EP1534268A4 (en) | TYROSINE KINASE INHIBITORS | |
| EP1581539A4 (en) | NEW TYROSINE KINASE HEMMER | |
| HK1071758A1 (en) | Pyrazolopyridines as cyclin dependent kinase inhibitors | |
| AU2003275282A8 (en) | Novel tyrosine kinase inhibitors | |
| AU2003237446A1 (en) | Pyrazole-derivatives as p38 kinase inhibitors | |
| AU2003254051A8 (en) | Pyrazolopyrimidines as kinase inhibitors | |
| PL378116A1 (pl) | Heterocykliczne inhibitory kinazy |