SI2187876T1 - Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol - Google Patents

Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol

Info

Publication number
SI2187876T1
SI2187876T1 SI200731082T SI200731082T SI2187876T1 SI 2187876 T1 SI2187876 T1 SI 2187876T1 SI 200731082 T SI200731082 T SI 200731082T SI 200731082 T SI200731082 T SI 200731082T SI 2187876 T1 SI2187876 T1 SI 2187876T1
Authority
SI
Slovenia
Prior art keywords
ethanol
influence
controlled release
resistance against
release pharmaceutical
Prior art date
Application number
SI200731082T
Other languages
Slovenian (sl)
Inventor
Hans-Ulrich Petereit
Hema Ravishankar
Ashwini Samel
Original Assignee
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh
Publication of SI2187876T1 publication Critical patent/SI2187876T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200731082T 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol SI2187876T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2130CH2007 2007-09-21
PCT/EP2007/060131 WO2009036812A1 (en) 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
EP07820537A EP2187876B1 (en) 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol

Publications (1)

Publication Number Publication Date
SI2187876T1 true SI2187876T1 (en) 2012-12-31

Family

ID=39232916

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731082T SI2187876T1 (en) 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol

Country Status (13)

Country Link
US (1) US9700520B2 (en)
EP (1) EP2187876B1 (en)
JP (1) JP5204847B2 (en)
KR (1) KR101424653B1 (en)
CN (1) CN101801357B (en)
BR (1) BRPI0721990B8 (en)
CA (1) CA2699227C (en)
ES (1) ES2393934T3 (en)
IL (1) IL203901A (en)
MX (1) MX2010003032A (en)
PL (1) PL2187876T3 (en)
SI (1) SI2187876T1 (en)
WO (1) WO2009036812A1 (en)

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JP2004512354A (en) 2000-10-30 2004-04-22 ユーロ−セルティーク，エス．エイ． Hydrocodone controlled release formulation
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
EP2187873B1 (en) 2007-08-13 2018-07-25 Abuse Deterrent Pharmaceutical Llc Abuse resistant drugs, method of use and method of making
EP2341899B1 (en) * 2008-09-24 2014-12-17 Evonik Röhm GmbH Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
WO2010034344A1 (en) 2008-09-24 2010-04-01 Evonik Röhm Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
KR101571198B1 (en) * 2009-03-18 2015-11-23 에보니크 룀 게엠베하 Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising neutral vinyl polymers and excipients
US20110311631A1 (en) * 2009-03-18 2011-12-22 Evonik Röhm Gmbh Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising a polymer mixture and excipients
DE102009028076A1 (en) * 2009-07-29 2011-02-03 Evonik Röhm Gmbh Coating composition for dip coating of capsule halves
US9107451B2 (en) 2009-07-29 2015-08-18 Evonik Röhm Gmbh Coating composition for the dip coating of capsule halves
FR2951378B1 (en) * 2009-10-16 2012-06-01 Flamel Tech Sa ANTI-MEASURING SOLID ORAL PHARMACEUTICAL FORM WITH A SPECIFIC MODIFIED RELEASE PROFILE
EP2371356B1 (en) 2010-03-12 2012-12-19 Phoeme GmbH Multi-particle pharmaceutical formulation for colon absorption
WO2011143120A1 (en) 2010-05-11 2011-11-17 Cima Labs Inc. Alcoholres i stant metoprolol - containing extended - release oral dosage forms
US9492394B2 (en) * 2010-08-18 2016-11-15 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical formulation comprising one or more salts of alginic acid
AU2011370763A1 (en) 2011-06-17 2013-10-03 Evonik Rohm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
CA2839689C (en) 2011-06-17 2018-05-01 Evonik Roehm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
HUE030548T2 (en) * 2011-06-17 2017-05-29 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
HUE031251T2 (en) 2011-06-30 2017-07-28 Develco Pharma Schweiz Ag Controlled release oral dosage form comprising oxycodone
US20140323512A1 (en) * 2011-10-18 2014-10-30 Purdue Pharma L.P. Acrylic Polymer Formulations
US20140275038A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
CA2919892C (en) 2013-08-12 2019-06-18 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US20150118300A1 (en) 2013-10-31 2015-04-30 Cima Labs Inc. Immediate Release Abuse-Deterrent Granulated Dosage Forms
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
GB201411704D0 (en) * 2014-07-01 2014-08-13 Lucideon Ltd Coated particles
EP3169315B1 (en) 2014-07-17 2020-06-24 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2018044895A1 (en) * 2016-08-29 2018-03-08 Cima Labs Inc. Immediate release dosage forms with abuse deterrence and alcohol resistance
EP3681918B1 (en) 2017-09-14 2022-01-12 Evonik Operations GmbH Polymer and dosage form with sustained release properties and resistance against the influence of ethanol
CN112469399A (en) 2018-03-09 2021-03-09 赢创运营有限公司 Polymer mixtures resistant to the effects of ethanol
CN108822816A (en) * 2018-06-25 2018-11-16 中国石油集团渤海钻探工程有限公司 A kind of molten GEL USED FOR PLUGGING WELL LOST CIRCULATION of loose sand theobromine and preparation method thereof
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
US20220062200A1 (en) 2019-05-07 2022-03-03 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
EP3965733A4 (en) 2019-05-07 2023-01-11 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine

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JP5704789B2 (en) * 2005-01-28 2015-04-22 ユーロ−セルティーク エス．エイ． Alcohol resistant dosage form
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HU227490B1 (en) 2005-08-26 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Sustained release pharmaceutical preparation containing carvedilol

Also Published As

Publication number Publication date
EP2187876A1 (en) 2010-05-26
KR20100059885A (en) 2010-06-04
CA2699227C (en) 2014-12-02
US20100226978A1 (en) 2010-09-09
BRPI0721990B1 (en) 2019-12-10
EP2187876B1 (en) 2012-08-22
JP2010539197A (en) 2010-12-16
CN101801357B (en) 2013-08-07
PL2187876T3 (en) 2013-01-31
KR101424653B1 (en) 2014-08-06
IL203901A (en) 2015-03-31
ES2393934T3 (en) 2013-01-02
WO2009036812A1 (en) 2009-03-26
BRPI0721990B8 (en) 2022-07-05
JP5204847B2 (en) 2013-06-05
MX2010003032A (en) 2010-04-09
CN101801357A (en) 2010-08-11
BRPI0721990A2 (en) 2014-03-18
CA2699227A1 (en) 2009-03-26
US9700520B2 (en) 2017-07-11

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