SI20750A - Uporaba defektnega rekombinantnega virusa, ki vsebuje nukleinsko kislino, ki kodira za angiogenski faktor, za zdravljenje pljučne arterijske hipertenzije - Google Patents

Uporaba defektnega rekombinantnega virusa, ki vsebuje nukleinsko kislino, ki kodira za angiogenski faktor, za zdravljenje pljučne arterijske hipertenzije Download PDF

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Publication number
SI20750A
SI20750A SI200020023A SI200020023A SI20750A SI 20750 A SI20750 A SI 20750A SI 200020023 A SI200020023 A SI 200020023A SI 200020023 A SI200020023 A SI 200020023A SI 20750 A SI20750 A SI 20750A
Authority
SI
Slovenia
Prior art keywords
vegf
fgf
recombinant
vector
nucleic acid
Prior art date
Application number
SI200020023A
Other languages
English (en)
Slovenian (sl)
Inventor
Serge Adnot
Didier Branellec
Original Assignee
Aventis Pharma S.A.
Institut National De La Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9905272A external-priority patent/FR2792531B1/fr
Application filed by Aventis Pharma S.A., Institut National De La Sante filed Critical Aventis Pharma S.A.
Publication of SI20750A publication Critical patent/SI20750A/sl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • C07K14/501Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI200020023A 1999-04-26 2000-04-21 Uporaba defektnega rekombinantnega virusa, ki vsebuje nukleinsko kislino, ki kodira za angiogenski faktor, za zdravljenje pljučne arterijske hipertenzije SI20750A (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9905272A FR2792531B1 (fr) 1999-04-26 1999-04-26 Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire
US13973499P 1999-06-18 1999-06-18
PCT/FR2000/001060 WO2000065043A1 (fr) 1999-04-26 2000-04-21 Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire

Publications (1)

Publication Number Publication Date
SI20750A true SI20750A (sl) 2002-06-30

Family

ID=26234932

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200020023A SI20750A (sl) 1999-04-26 2000-04-21 Uporaba defektnega rekombinantnega virusa, ki vsebuje nukleinsko kislino, ki kodira za angiogenski faktor, za zdravljenje pljučne arterijske hipertenzije

Country Status (17)

Country Link
US (1) US20020086004A1 (pt)
EP (1) EP1173564A1 (pt)
JP (1) JP2002543097A (pt)
KR (1) KR20020001846A (pt)
CN (1) CN1376197A (pt)
AU (1) AU782833B2 (pt)
BR (1) BR0010034A (pt)
CA (1) CA2370404A1 (pt)
CZ (1) CZ20013813A3 (pt)
HU (1) HUP0200961A3 (pt)
IL (1) IL145834A0 (pt)
MX (1) MXPA01010849A (pt)
NO (1) NO20015223L (pt)
NZ (1) NZ515233A (pt)
PL (1) PL351114A1 (pt)
SI (1) SI20750A (pt)
WO (1) WO2000065043A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020072489A1 (en) * 1998-10-13 2002-06-13 Whitehouse Martha J. Angiogenically effective unit dose of FGF-2 and method of use
US7223724B1 (en) * 1999-02-08 2007-05-29 Human Genome Sciences, Inc. Use of vascular endothelial growth factor to treat photoreceptor cells
MXPA02003434A (es) * 2000-08-04 2002-09-02 Human Genome Sciences Inc Factor de crecimiento endotelial vascular 2.
DK1385864T3 (da) * 2001-04-13 2010-08-16 Human Genome Sciences Inc Anti-VEGF-2-antistoffer
WO2002083849A2 (en) * 2001-04-13 2002-10-24 Human Genome Sciences, Inc. Vascular endothelial growth factor 2
US20050232921A1 (en) * 2001-04-13 2005-10-20 Rosen Craig A Vascular endothelial growth factor 2
KR100697321B1 (ko) * 2005-07-27 2007-03-20 박기랑 VEGF-A, VEGF-B 및 VEGF-C의 안티센스cDNA를 함유하는 재조합 아데노-연관바이러스(rAAV) 및 이를 함유하는 대장암, 방광암및/또는 폐암 특이적 유전자 치료제
RU2558794C2 (ru) * 2009-06-25 2015-08-10 Байолидерс Корпорейшн Адъювантная композиция, содержащая наночастицы поли-гамма-глутаминовой кислоты-хитозан
CN105833248A (zh) * 2016-04-27 2016-08-10 温州医科大学附属第医院 成纤维细胞生长因子21的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717495B1 (fr) * 1994-03-18 1996-04-12 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
AU2051297A (en) * 1996-02-15 1997-09-02 Chiron Corporation Gene therapy method using fgf-5
EP0941116B1 (en) * 1996-11-01 2005-01-19 Ark Therapeutics Limited Use of vegf for the manufacture of a medicament for the treatment or prevention of intimal hyperplasia and delivery device
WO1998037185A2 (en) * 1997-02-20 1998-08-27 The Board Of Regents Of The University Of Texas System Vectors for controlled gene expression
US6423751B1 (en) * 1998-07-14 2002-07-23 The Brigham And Women's Hospital, Inc. Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization

Also Published As

Publication number Publication date
JP2002543097A (ja) 2002-12-17
HUP0200961A3 (en) 2004-11-29
PL351114A1 (en) 2003-03-24
CZ20013813A3 (cs) 2002-02-13
NO20015223D0 (no) 2001-10-25
BR0010034A (pt) 2002-01-15
MXPA01010849A (es) 2002-11-07
WO2000065043A1 (fr) 2000-11-02
HUP0200961A2 (hu) 2002-07-29
IL145834A0 (en) 2002-07-25
AU4301700A (en) 2000-11-10
AU782833B2 (en) 2005-09-01
NZ515233A (en) 2004-08-27
CA2370404A1 (fr) 2000-11-02
KR20020001846A (ko) 2002-01-09
NO20015223L (no) 2001-10-25
CN1376197A (zh) 2002-10-23
US20020086004A1 (en) 2002-07-04
EP1173564A1 (fr) 2002-01-23

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Effective date: 20071205