SI1521600T1 - Bisaciloksipropicistein-konjugati in njihova uporaba - Google Patents

Bisaciloksipropicistein-konjugati in njihova uporaba

Info

Publication number
SI1521600T1
SI1521600T1 SI200331197T SI200331197T SI1521600T1 SI 1521600 T1 SI1521600 T1 SI 1521600T1 SI 200331197 T SI200331197 T SI 200331197T SI 200331197 T SI200331197 T SI 200331197T SI 1521600 T1 SI1521600 T1 SI 1521600T1
Authority
SI
Slovenia
Prior art keywords
formula
ooc
coo
polyoxyethylene
new
Prior art date
Application number
SI200331197T
Other languages
English (en)
Inventor
Peter Muhlradt
Michael Morr
Original Assignee
Helmholtz Zentrum Infektionsforschung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz Zentrum Infektionsforschung Gmbh filed Critical Helmholtz Zentrum Infektionsforschung Gmbh
Publication of SI1521600T1 publication Critical patent/SI1521600T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
SI200331197T 2002-07-19 2003-07-18 Bisaciloksipropicistein-konjugati in njihova uporaba SI1521600T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02016066A EP1382352A1 (de) 2002-07-19 2002-07-19 Bisacyloxypropylcystein-Konjugate und deren Verwendung
EP03765055A EP1521600B1 (de) 2002-07-19 2003-07-18 Bisacyloxypropylcystein-konjugate und deren verwendung
PCT/EP2003/007892 WO2004009125A2 (de) 2002-07-19 2003-07-18 Bisacyloxypropylcystein-konjugate und deren verwendung

Publications (1)

Publication Number Publication Date
SI1521600T1 true SI1521600T1 (sl) 2008-08-31

Family

ID=29762661

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331197T SI1521600T1 (sl) 2002-07-19 2003-07-18 Bisaciloksipropicistein-konjugati in njihova uporaba

Country Status (13)

Country Link
US (1) US7316996B2 (sl)
EP (3) EP1382352A1 (sl)
AT (1) ATE385422T1 (sl)
AU (1) AU2003251002B2 (sl)
CA (1) CA2489010C (sl)
CY (1) CY1107929T1 (sl)
DE (1) DE50309128D1 (sl)
DK (1) DK1521600T3 (sl)
ES (1) ES2301832T3 (sl)
HK (1) HK1074802A1 (sl)
PT (1) PT1521600E (sl)
SI (1) SI1521600T1 (sl)
WO (1) WO2004009125A2 (sl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652586A1 (de) * 1996-12-17 1998-06-18 Biotechnolog Forschung Gmbh Dhc-Peptid und Mittel
AU2002337592A1 (en) 2001-09-24 2003-04-07 Nice Systems Ltd. System and method for the automatic control of video frame rate
EP1484064A1 (en) * 2003-06-04 2004-12-08 Gesellschaft für Biotechnologische Forschung Therapeutical composition containing dentritic cells and use thereof
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
EP1782826A1 (en) 2005-11-08 2007-05-09 GBF Gesellschaft für Biotechnologische Forschung mbH PQS and c-diGMP and its conjugates as adjuvants and their uses in pharmaceutical compositions
EP1787660A1 (en) * 2005-11-22 2007-05-23 GBF Gesellschaft für Biotechnologische Forschung mbH New adjuvants on the basis of bisacyloxypropylcysteine conjugates and their uses in pharmaceutical compositions
EP1897557A1 (en) 2006-09-07 2008-03-12 Helmholtz-Zentrum für Infektionsforschung GmbH Use of glycolipids as adjuvants
DE102006045453A1 (de) * 2006-09-26 2008-04-03 Khs Ag Transportsystem
EP2196196A1 (en) * 2008-12-10 2010-06-16 Medipol S.A. Compound, medicament, vaccine composition and nanocapsules
EP2305283A1 (en) * 2009-09-24 2011-04-06 Helmholtz-Zentrum für Infektionsforschung GmbH Pharmaceutical compositions for treating dysregulated inflammatory diseases
EP2338521A1 (en) * 2009-12-28 2011-06-29 Helmholtz-Zentrum für Infektionsforschung GmbH Lipopeptide- and lipoprotein-conjugates and its use
WO2011119759A1 (en) * 2010-03-23 2011-09-29 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
CN103189072B (zh) 2010-09-22 2018-02-09 因纳瓦克私人有限公司 免疫刺激方法
JP2013542928A (ja) * 2010-09-30 2013-11-28 フランバックス ソチエタ レスポンサビリタ リミテ ビロソーム粒子の生成
EP2522350B1 (de) 2011-05-12 2013-07-31 Immunopharm AG Verwendung der Wirkstoffkombination aus einem 1-Diethylaminoethyl-3-Chinoxalin-2-on Derivat und einem Oxysterol zur Durchbrechung von Resistenzen bei der Behandlung von Krebs und zur Erhöhung der Immunleistungsfähigkeit bei Krebs, bakteriellen und viralen Erkrankungen, Autoimmunerkrankungen, erhöhter Stress- und Umweltbelastung
CN105849087A (zh) * 2013-12-27 2016-08-10 诺华丝国际股份有限公司 乙氧基化表面活性剂
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions
CN115501125A (zh) * 2022-10-20 2022-12-23 澳门科技大学 用于修复皮肤损伤的h2s供体凝胶及h2s供体凝胶制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595732A (en) * 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5580563A (en) * 1992-05-01 1996-12-03 Tam; James P. Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
EP0604945A1 (en) * 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, its derivatives, production and use thereof
CA2128552A1 (en) * 1993-07-22 1995-01-23 Hida Tsuneaki Derivatives of 6,7-dihydroxy-4-thiaheptanoic acid and their use
DE19652586A1 (de) * 1996-12-17 1998-06-18 Biotechnolog Forschung Gmbh Dhc-Peptid und Mittel
AU775937B2 (en) * 1999-01-14 2004-08-19 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues

Also Published As

Publication number Publication date
DE50309128D1 (de) 2008-03-20
US7316996B2 (en) 2008-01-08
CA2489010A1 (en) 2004-01-29
US20060134061A1 (en) 2006-06-22
EP1382352A1 (de) 2004-01-21
WO2004009125A3 (de) 2004-05-27
CA2489010C (en) 2012-01-17
CY1107929T1 (el) 2013-09-04
AU2003251002A1 (en) 2004-02-09
EP1521600A2 (de) 2005-04-13
PT1521600E (pt) 2008-05-13
EP1521600B1 (de) 2008-02-06
AU2003251002B2 (en) 2009-02-26
WO2004009125A2 (de) 2004-01-29
ATE385422T1 (de) 2008-02-15
HK1074802A1 (en) 2005-11-25
ES2301832T3 (es) 2008-07-01
DK1521600T3 (da) 2008-06-09
EP1955713A1 (de) 2008-08-13

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