SG54525A1 - Multiphase soft gelatin dosage form - Google Patents

Multiphase soft gelatin dosage form

Info

Publication number
SG54525A1
SG54525A1 SG1997002161A SG1997002161A SG54525A1 SG 54525 A1 SG54525 A1 SG 54525A1 SG 1997002161 A SG1997002161 A SG 1997002161A SG 1997002161 A SG1997002161 A SG 1997002161A SG 54525 A1 SG54525 A1 SG 54525A1
Authority
SG
Singapore
Prior art keywords
dosage form
soft gelatin
gelatin dosage
multiphase
multiphase soft
Prior art date
Application number
SG1997002161A
Other languages
English (en)
Inventor
Michael R Hoy
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of SG54525A1 publication Critical patent/SG54525A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/80Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG1997002161A 1996-06-28 1997-06-25 Multiphase soft gelatin dosage form SG54525A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/671,979 US6024980A (en) 1996-06-28 1996-06-28 Multiphase soft gelatin dosage form

Publications (1)

Publication Number Publication Date
SG54525A1 true SG54525A1 (en) 1998-11-16

Family

ID=24696660

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1997002161A SG54525A1 (en) 1996-06-28 1997-06-25 Multiphase soft gelatin dosage form

Country Status (24)

Country Link
US (1) US6024980A (es)
EP (1) EP0815855B1 (es)
JP (1) JPH10182437A (es)
KR (1) KR980000438A (es)
CN (1) CN1172642A (es)
AR (1) AR007648A1 (es)
AT (1) ATE223707T1 (es)
AU (1) AU2620197A (es)
BR (1) BR9703771A (es)
CO (1) CO4900025A1 (es)
CZ (1) CZ205697A3 (es)
DE (1) DE69715319T2 (es)
DK (1) DK0815855T3 (es)
ES (1) ES2183089T3 (es)
HU (1) HUP9701113A2 (es)
ID (1) ID17794A (es)
IL (1) IL121145A0 (es)
NO (1) NO972963L (es)
NZ (1) NZ328182A (es)
PL (1) PL320815A1 (es)
PT (1) PT815855E (es)
SG (1) SG54525A1 (es)
TN (1) TNSN97111A1 (es)
ZA (1) ZA975767B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US7763276B1 (en) 1999-02-26 2010-07-27 Shionogi & Co., Ltd. Chewable soft capsules having improved administration properties and process for producing the same
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
EP1427400A2 (en) * 2001-09-18 2004-06-16 The North West University Triclosan dosage form
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
AU2003272601B2 (en) * 2002-09-20 2009-05-07 Alpharma Pharmaceuticals, Llc Sustained-release opioid formulations and methods of use
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20040185032A1 (en) * 2003-03-18 2004-09-23 David Burrell Compositions and methods for treating colic
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US20050249802A1 (en) * 2004-05-06 2005-11-10 The Procter & Gamble Company Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
EP3064064A1 (en) * 2009-09-30 2016-09-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
WO2013155430A1 (en) * 2012-04-13 2013-10-17 Banner Pharmacaps, Inc. Soft elastic capsules containing tablets and liquid or semisolid fills and methods for their manufacture
JP5922851B2 (ja) 2012-11-30 2016-05-24 アキュラ・ファーマシューティカルズ・インコーポレーテッド 活性医薬成分の自己制御放出
CN105307634B (zh) 2013-03-15 2020-03-10 沃纳奇尔科特有限责任公司 含有改性瓜尔胶的药物软明胶胶囊剂型
WO2015023675A2 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
AU2015237723B2 (en) 2014-03-26 2018-04-26 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
BR112020016884A2 (pt) * 2018-02-26 2020-12-15 R.P. Scherer Technologies, Llc Forma de dosagem farmacêutica para uma emulsão de simeticona e loperamida
KR20210053946A (ko) * 2018-08-31 2021-05-12 아틱 테라퓨틱스, 엘엘씨 피내 적용을 위한 신규한 국소 제형 및 그것의 용도

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4486412A (en) * 1983-03-15 1984-12-04 Pharmacaps, Inc. Encapsulated antacid dispersions
WO1986004501A1 (en) * 1985-01-31 1986-08-14 Fujisawa Pharmaceutical Co., Ltd. Soft multi-chamber capsule and method of and apparatus for manufacturing same
JPS61189230A (ja) * 1985-02-19 1986-08-22 Nippon Kayaku Co Ltd エトポシド製剤
GB8507779D0 (en) * 1985-03-26 1985-05-01 Fujisawa Pharmaceutical Co Drug carrier
US4639846A (en) * 1985-08-16 1987-01-27 Bbc Brown, Boveri & Company, Limited Method and compensating device for compensating current oscillations
US5209978A (en) * 1985-12-26 1993-05-11 Taisho Pharmaceutical Co., Ltd. Seamless soft capsule and production thereof
DE3600084A1 (de) * 1986-01-03 1987-07-09 Scherer Gmbh R P Formkoerper sowie verfahren und vorrichtung zur herstellung eines solchen formkoerpers
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
DE3727894A1 (de) * 1987-08-21 1989-03-02 Stephan Dieter Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
FR2624012B1 (fr) * 1987-12-07 1991-05-31 Fdb Ste Civile Rech Nouvelles compositions pharmaceutiques a action hypnotique a base d'hydrate de chloral
US4956184A (en) * 1988-05-06 1990-09-11 Alcide Corporation Topical treatment of genital herpes lesions
US4935243A (en) * 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
US5073384A (en) * 1989-10-19 1991-12-17 Valentine Enterprises, Inc. Maltodextrin/defoaming composition combinate
GB8926612D0 (en) * 1989-11-24 1990-01-17 Erba Farmitalia Pharmaceutical compositions
IE64128B1 (en) * 1990-02-26 1995-07-12 Byrne Rynne Holdings Ltd A pharmaceutical composition
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
GR1002332B (el) * 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη.
US5501857A (en) * 1992-07-24 1996-03-26 Midwestern Bio-Ag Products & Services, Inc. Oral nutritional and dietary composition
KR960703335A (ko) * 1993-06-30 1996-08-17 후지야마 아키라 캡슐화된 약제(encapsulated medicine)
US5725846A (en) * 1995-03-02 1998-03-10 The Gillette Company Clear antiperspirant stick containing dibenzylidene alditol and hydroxyalkyl cellulose

Also Published As

Publication number Publication date
DE69715319D1 (de) 2002-10-17
NO972963D0 (no) 1997-06-25
EP0815855B1 (en) 2002-09-11
CN1172642A (zh) 1998-02-11
KR980000438A (ko) 1998-03-30
DE69715319T2 (de) 2003-01-23
CO4900025A1 (es) 2000-03-27
JPH10182437A (ja) 1998-07-07
MX9704846A (es) 1998-07-31
ES2183089T3 (es) 2003-03-16
EP0815855A1 (en) 1998-01-07
CZ205697A3 (cs) 1998-01-14
PT815855E (pt) 2003-01-31
NZ328182A (en) 1998-11-25
AR007648A1 (es) 1999-11-10
AU2620197A (en) 1998-01-15
NO972963L (no) 1997-12-29
BR9703771A (pt) 1998-09-01
HU9701113D0 (en) 1997-08-28
HUP9701113A2 (hu) 1998-08-28
ID17794A (id) 1998-01-29
DK0815855T3 (da) 2003-01-06
PL320815A1 (en) 1998-01-05
ATE223707T1 (de) 2002-09-15
TNSN97111A1 (fr) 2005-03-15
IL121145A0 (en) 1997-11-20
ZA975767B (en) 1998-12-28
US6024980A (en) 2000-02-15

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