SG2395G - Steroids having an enamide or enimide group and their preparation - Google Patents

Steroids having an enamide or enimide group and their preparation

Info

Publication number
SG2395G
SG2395G SG2395A SG2395A SG2395G SG 2395 G SG2395 G SG 2395G SG 2395 A SG2395 A SG 2395A SG 2395 A SG2395 A SG 2395A SG 2395 G SG2395 G SG 2395G
Authority
SG
Singapore
Prior art keywords
enimide
enamide
steroids
preparation
group
Prior art date
Application number
SG2395A
Other languages
English (en)
Inventor
Verian Henry Vanrheenen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/576,590 external-priority patent/US4500461A/en
Priority claimed from US06/576,674 external-priority patent/US4548748A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to SG2395A priority Critical patent/SG2395G/en
Publication of SG2395G publication Critical patent/SG2395G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
SG2395A 1984-02-03 1995-01-09 Steroids having an enamide or enimide group and their preparation SG2395G (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG2395A SG2395G (en) 1984-02-03 1995-01-09 Steroids having an enamide or enimide group and their preparation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/576,590 US4500461A (en) 1984-02-03 1984-02-03 Cyanohydrin process
US06/576,674 US4548748A (en) 1984-02-03 1984-02-03 Cyanohydrin process
SG2395A SG2395G (en) 1984-02-03 1995-01-09 Steroids having an enamide or enimide group and their preparation

Publications (1)

Publication Number Publication Date
SG2395G true SG2395G (en) 1995-06-16

Family

ID=27076992

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2395A SG2395G (en) 1984-02-03 1995-01-09 Steroids having an enamide or enimide group and their preparation

Country Status (4)

Country Link
EP (1) EP0153001B1 (de)
DE (1) DE3585547D1 (de)
HK (1) HK47695A (de)
SG (1) SG2395G (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden
US5352809A (en) * 1986-10-10 1994-10-04 Gist-Brocades N.V. 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids
CA1317283C (en) * 1986-11-05 1993-05-04 Douglas Alan Livingston Steroidal 17–-silyl ethers and process to corticoids and progesterones
JP2610674B2 (ja) * 1987-08-14 1997-05-14 ジ・アップジョン・カンパニー ステロイド１７‐シアノヒドリン類のコルチコイド類への変換
DE3931064A1 (de) * 1989-09-14 1991-03-28 Schering Ag Verfahren zur herstellung von progesteron-derivaten
AU684946B2 (en) * 1994-05-09 1998-01-08 Pharmacia & Upjohn Company SYNTHESIS OF 17B CYANO-3-ETHOXY-17a-HYDROXY-6-METHYLANDROSTA-3,5,9-(11)-TRIEN 9(11)-triene
CN104072565B (zh) * 2014-07-11 2017-03-01 山东众诚药业股份有限公司 一种高收率的17α‑羟基黄体酮的简捷制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2486947A1 (fr) * 1980-07-15 1982-01-22 Roussel Uclaf Nouveaux derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur application a la preparation des steroides 17a-hydroxy 20-ceto
FR2493324B1 (de) * 1980-11-05 1983-01-21 Roussel Uclaf
JPS5788197A (en) * 1980-11-21 1982-06-01 Mitsubishi Chem Ind Ltd Preparation of synthetic intermediate of corticoids

Also Published As

Publication number Publication date
EP0153001A2 (de) 1985-08-28
HK47695A (en) 1995-04-07
EP0153001A3 (en) 1986-03-19
DE3585547D1 (de) 1992-04-16
EP0153001B1 (de) 1992-03-11

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