SG194896A1 - Compositions, methods & systems for respiratory delivery of two or more active agents - Google Patents
Compositions, methods & systems for respiratory delivery of two or more active agents Download PDFInfo
- Publication number
- SG194896A1 SG194896A1 SG2013083431A SG2013083431A SG194896A1 SG 194896 A1 SG194896 A1 SG 194896A1 SG 2013083431 A SG2013083431 A SG 2013083431A SG 2013083431 A SG2013083431 A SG 2013083431A SG 194896 A1 SG194896 A1 SG 194896A1
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- Singapore
- Prior art keywords
- active agent
- suspension
- less
- particles
- hours
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- 239000013543 active substance Substances 0.000 title claims abstract description 627
- 239000000203 mixture Substances 0.000 title claims abstract description 449
- 238000000034 method Methods 0.000 title claims abstract description 166
- 230000000241 respiratory effect Effects 0.000 title description 18
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- 239000000725 suspension Substances 0.000 claims abstract description 500
- 230000002685 pulmonary effect Effects 0.000 claims abstract description 15
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- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 claims description 95
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- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 claims description 37
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Classifications
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/036868 WO2012158166A1 (fr) | 2011-05-17 | 2011-05-17 | Compositions, procédés et systèmes d'administration par voie respiratoire d'au moins deux agents actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG194896A1 true SG194896A1 (en) | 2013-12-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013083431A SG194896A1 (en) | 2011-05-17 | 2011-05-17 | Compositions, methods & systems for respiratory delivery of two or more active agents |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP2709447A4 (fr) |
| JP (1) | JP2014518871A (fr) |
| KR (1) | KR20140032404A (fr) |
| CN (1) | CN103687483A (fr) |
| AU (1) | AU2011368334A1 (fr) |
| BR (1) | BR112013029507A2 (fr) |
| CA (1) | CA2835927A1 (fr) |
| EA (1) | EA201490991A1 (fr) |
| IL (1) | IL229260A0 (fr) |
| MX (1) | MX2013013440A (fr) |
| RU (1) | RU2013155903A (fr) |
| SG (1) | SG194896A1 (fr) |
| WO (1) | WO2012158166A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| AU2010253776B2 (en) | 2009-05-29 | 2015-01-22 | Pearl Therapeutics, Inc. | Compositions for pulmonary delivery of long-acting muscarinic antagonists and long-acting B2 adrenergic receptor agonists and associated methods and systems |
| US9682038B2 (en) | 2013-01-31 | 2017-06-20 | Prosonix Limited | Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy |
| WO2014144894A1 (fr) | 2013-03-15 | 2014-09-18 | Pearl Therapeutics, Inc. | Procedes et systemes de conditionnement de matieres cristallines particulaires |
| RU2015154720A (ru) * | 2013-05-22 | 2017-06-27 | Перл Терапьютикс, Инк. | Композиции, способы и системы для респираторной доставки трех или более активных средств |
| TN2016000261A1 (en) | 2013-12-30 | 2017-10-06 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination. |
| ES2666905T4 (es) * | 2013-12-30 | 2018-06-07 | Chiesi Farmaceutici S.P.A. | Composición en solución para aerosol estable presurizada de una combinación de bromuro de glicopirronio y formoterol |
| MY181647A (en) | 2014-09-09 | 2020-12-30 | Vectura Ltd | Formulation comprising glycopyrrolate, method and apparatus |
| US20160310410A1 (en) | 2015-04-24 | 2016-10-27 | Glenmark Specialty S.A. | Pharmaceutical compositions comprising arformoterol and glycopyrronium |
| CA2983427C (fr) * | 2015-05-01 | 2024-04-23 | Board Of Regents, The University Of Texas System | Compositions matricielles fragiles a medicaments multiples |
| CN105125542A (zh) * | 2015-08-23 | 2015-12-09 | 杭州紫金医药科技有限公司 | 含噻托溴铵和福莫特罗的药物组合物及其用途和制剂 |
| CN106880637B (zh) * | 2015-12-15 | 2021-01-29 | 天津金耀集团有限公司 | 一种环索奈德福莫特罗噻托溴铵复方干粉吸入剂组合物 |
| CN106880636A (zh) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | 一种环索奈德单方和复方干粉吸入剂组合物 |
| CN106943350A (zh) * | 2017-03-14 | 2017-07-14 | 上海现代药物制剂工程研究中心有限公司 | 含毒蕈碱受体拮抗剂和β2受体激动剂的气雾剂及制备方法 |
| WO2020100040A1 (fr) * | 2018-11-12 | 2020-05-22 | 3M Innovative Properties Company | Formulation d'uméclidinium et de vilantérol et inhalateur |
| WO2021071967A1 (fr) * | 2019-10-09 | 2021-04-15 | Island Breeze Systems Ca, Llc | Compositions permettant l'administration par voie pulmonaire de cannabinoïdes, méthodes et systèmes associés |
| CN111467498A (zh) * | 2020-05-14 | 2020-07-31 | 王兆霖 | 药物组合物制剂 |
| TW202241410A (zh) * | 2021-01-08 | 2022-11-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | 可經由定量吸入器遞送的藥物組合物 |
| MX2024000465A (es) * | 2021-07-09 | 2024-04-05 | Astrazeneca Pharmaceuticals Lp | Composiciones, metodos y sistemas para la administracion de farmacos en aerosol. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| IL135126A0 (en) * | 1997-09-29 | 2001-05-20 | Inhale Therapeutic Syst | Perforated microparticles and methods of use and preparation thereof |
| GB9903759D0 (en) * | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
| SE527190C2 (sv) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Inhalatoranordning samt kombinerade doser av en beta2-agonist, ett antikolinergiskt medel och ett antiinflammatorisk steroid |
| SI1718336T1 (sl) * | 2004-02-06 | 2008-10-31 | Meda Pharma Gmbh & Co Kg | Nova kombinacija antiholinergika in beta mimetikov za zdravljenje respiratornih bolezni |
| US8815258B2 (en) * | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| AU2010253776B2 (en) * | 2009-05-29 | 2015-01-22 | Pearl Therapeutics, Inc. | Compositions for pulmonary delivery of long-acting muscarinic antagonists and long-acting B2 adrenergic receptor agonists and associated methods and systems |
-
2011
- 2011-05-17 SG SG2013083431A patent/SG194896A1/en unknown
- 2011-05-17 KR KR1020137030446A patent/KR20140032404A/ko not_active Application Discontinuation
- 2011-05-17 AU AU2011368334A patent/AU2011368334A1/en not_active Abandoned
- 2011-05-17 JP JP2014511329A patent/JP2014518871A/ja active Pending
- 2011-05-17 CN CN201180072341.4A patent/CN103687483A/zh active Pending
- 2011-05-17 CA CA2835927A patent/CA2835927A1/fr not_active Abandoned
- 2011-05-17 BR BR112013029507A patent/BR112013029507A2/pt not_active IP Right Cessation
- 2011-05-17 EA EA201490991A patent/EA201490991A1/ru unknown
- 2011-05-17 RU RU2013155903/15A patent/RU2013155903A/ru not_active Application Discontinuation
- 2011-05-17 MX MX2013013440A patent/MX2013013440A/es unknown
- 2011-05-17 WO PCT/US2011/036868 patent/WO2012158166A1/fr active Application Filing
- 2011-05-17 EP EP11865780.8A patent/EP2709447A4/fr not_active Withdrawn
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2013
- 2013-11-05 IL IL229260A patent/IL229260A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2013155903A (ru) | 2015-06-27 |
| EA201490991A1 (ru) | 2014-09-30 |
| CA2835927A1 (fr) | 2012-11-22 |
| WO2012158166A1 (fr) | 2012-11-22 |
| JP2014518871A (ja) | 2014-08-07 |
| IL229260A0 (en) | 2014-01-30 |
| EP2709447A4 (fr) | 2014-10-22 |
| CN103687483A (zh) | 2014-03-26 |
| BR112013029507A2 (pt) | 2019-09-24 |
| KR20140032404A (ko) | 2014-03-14 |
| EP2709447A1 (fr) | 2014-03-26 |
| MX2013013440A (es) | 2014-06-05 |
| AU2011368334A1 (en) | 2013-11-21 |
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