SG146431A1 - New benzo[a]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New benzo[a]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
SG146431A1
SG146431A1 SG200404562-1A SG2004045621A SG146431A1 SG 146431 A1 SG146431 A1 SG 146431A1 SG 2004045621 A SG2004045621 A SG 2004045621A SG 146431 A1 SG146431 A1 SG 146431A1
Authority
SG
Singapore
Prior art keywords
acridin
pyrano
compounds
preparation
pharmaceutical compositions
Prior art date
Application number
SG200404562-1A
Other languages
English (en)
Inventor
Michel Koch
Francois Tillequin
Sylvie Michel
John Hickman
Alain Pierre
Stephane Leonce
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of SG146431A1 publication Critical patent/SG146431A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG200404562-1A 2003-06-25 2004-06-17 New benzo[a]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them SG146431A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0307664A FR2856687B1 (fr) 2003-06-25 2003-06-25 Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
SG146431A1 true SG146431A1 (en) 2008-10-30

Family

ID=33396845

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200404562-1A SG146431A1 (en) 2003-06-25 2004-06-17 New benzo[a]pyrano[3,2-h]acridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US7276512B2 (no)
EP (1) EP1491544A1 (no)
JP (1) JP2005041864A (no)
KR (1) KR20050001451A (no)
CN (1) CN1289502C (no)
AR (1) AR045695A1 (no)
AU (1) AU2004202864A1 (no)
BR (1) BRPI0402500A (no)
CA (1) CA2472294A1 (no)
EA (1) EA007790B1 (no)
FR (1) FR2856687B1 (no)
GE (1) GEP20063874B (no)
HK (1) HK1070360A1 (no)
MA (1) MA27096A1 (no)
MX (1) MXPA04006177A (no)
NO (1) NO20042447L (no)
NZ (1) NZ533747A (no)
SG (1) SG146431A1 (no)
ZA (1) ZA200405074B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2695162T3 (es) * 2013-04-29 2019-01-02 Nerviano Medical Sciences Srl Nuevos derivados de morfolinil antraciclina
IL255290B2 (en) 2015-04-27 2024-01-01 Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct Substances that bind to EGF1 and their use in the treatment of inflammatory diseases and tumors
CN110105318B (zh) * 2019-06-21 2021-04-09 南京林业大学 一种α-吡喃酮类化合物的绿色合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032491A1 (fr) * 1997-12-19 1999-07-01 Adir Et Compagnie Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1061081A1 (fr) * 1999-06-16 2000-12-20 Adir Et Compagnie Nouveaux dérivés de carboxylate de 7-oxo-2,3,7,14-tétrahydro-1H-benzo(b)pyrano(3,2-h)acridine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP1297835A1 (fr) * 2001-07-25 2003-04-02 Les Laboratoires Servier Dérivés de benzo[b]pyrano[3,2-h]acridin-7-one, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732204A (en) * 1967-07-17 1973-05-08 Lilly Co Eli Synthesis of acronycine and related compounds
US3943137A (en) * 1973-07-09 1976-03-09 University Of Kansas Endowment Association Acronycine derivatives
GB9318935D0 (en) * 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives
US5428040A (en) * 1993-08-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
FR2716197B1 (fr) * 1994-02-17 1996-04-19 Adir Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032491A1 (fr) * 1997-12-19 1999-07-01 Adir Et Compagnie Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1061081A1 (fr) * 1999-06-16 2000-12-20 Adir Et Compagnie Nouveaux dérivés de carboxylate de 7-oxo-2,3,7,14-tétrahydro-1H-benzo(b)pyrano(3,2-h)acridine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP1297835A1 (fr) * 2001-07-25 2003-04-02 Les Laboratoires Servier Dérivés de benzo[b]pyrano[3,2-h]acridin-7-one, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
, SYNTHESIS AND CYTOTOXIC AND ANTITUMOR ACTIVITY OF BENZO[B]PYRANO[3,2 *
-H]ACRIDIN-7-ONE ANALOGUES OF ACRONYCINE, SYNTHESIS OF 6- DIALKYAMINOA *

Also Published As

Publication number Publication date
NO20042447L (no) 2004-12-27
US7276512B2 (en) 2007-10-02
FR2856687B1 (fr) 2005-09-16
EA200400729A1 (ru) 2004-12-30
EP1491544A1 (fr) 2004-12-29
GEP20063874B (en) 2006-07-10
AR045695A1 (es) 2005-11-09
FR2856687A1 (fr) 2004-12-31
EA007790B1 (ru) 2007-02-27
CN1576277A (zh) 2005-02-09
MXPA04006177A (es) 2005-03-23
ZA200405074B (en) 2005-06-02
MA27096A1 (fr) 2004-12-20
KR20050001451A (ko) 2005-01-06
CN1289502C (zh) 2006-12-13
BRPI0402500A (pt) 2005-06-14
CA2472294A1 (fr) 2004-12-25
JP2005041864A (ja) 2005-02-17
AU2004202864A1 (en) 2005-01-13
US20040266753A1 (en) 2004-12-30
NZ533747A (en) 2005-12-23
HK1070360A1 (en) 2005-06-17

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