SG144146A1 - Adenosine receptor agonists - Google Patents

Adenosine receptor agonists

Info

Publication number
SG144146A1
SG144146A1 SG200804350-7A SG2008043507A SG144146A1 SG 144146 A1 SG144146 A1 SG 144146A1 SG 2008043507 A SG2008043507 A SG 2008043507A SG 144146 A1 SG144146 A1 SG 144146A1
Authority
SG
Singapore
Prior art keywords
receptor agonists
adenosine receptor
adenosine
agonists
receptor
Prior art date
Application number
SG200804350-7A
Other languages
English (en)
Inventor
Martyn Pritchard
Jacqueline Ouzman
Edward Savory
Giles Brown
Original Assignee
Cambridge Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2004/000902 external-priority patent/WO2004079329A2/fr
Priority claimed from GB0405012A external-priority patent/GB0405012D0/en
Priority claimed from GBGB0405009.2A external-priority patent/GB0405009D0/en
Priority claimed from GB0412262A external-priority patent/GB0412262D0/en
Priority claimed from GB0412261A external-priority patent/GB0412261D0/en
Priority claimed from GB0413627A external-priority patent/GB0413627D0/en
Priority claimed from GB0419718A external-priority patent/GB0419718D0/en
Priority claimed from GB0420063A external-priority patent/GB0420063D0/en
Priority claimed from GB0420615A external-priority patent/GB0420615D0/en
Application filed by Cambridge Biotechnology Ltd filed Critical Cambridge Biotechnology Ltd
Publication of SG144146A1 publication Critical patent/SG144146A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/06—Antiarrhythmics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
SG200804350-7A 2004-03-05 2005-03-04 Adenosine receptor agonists SG144146A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
PCT/GB2004/000902 WO2004079329A2 (fr) 2003-03-07 2004-03-05 Identification de composes therapeutiques
GB0405012A GB0405012D0 (en) 2004-03-05 2004-03-05 Therapeutic compounds
GBGB0405009.2A GB0405009D0 (en) 2004-03-05 2004-03-05 Analgesics
GB0412262A GB0412262D0 (en) 2004-06-02 2004-06-02 Use of compounds for the treatment of pain
GB0412261A GB0412261D0 (en) 2004-06-02 2004-06-02 Analgesics
GB0413627A GB0413627D0 (en) 2004-06-18 2004-06-18 Analgesics
GB0419718A GB0419718D0 (en) 2004-09-06 2004-09-06 Therapeutic compounds
GB0420063A GB0420063D0 (en) 2004-09-09 2004-09-09 Therapeutic compounds
GB0420615A GB0420615D0 (en) 2004-09-16 2004-09-16 Therapeutic compounds

Publications (1)

Publication Number Publication Date
SG144146A1 true SG144146A1 (en) 2008-07-29

Family

ID=34923594

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200804350-7A SG144146A1 (en) 2004-03-05 2005-03-04 Adenosine receptor agonists

Country Status (12)

Country Link
US (1) US20080221060A1 (fr)
EP (1) EP1749016A2 (fr)
JP (1) JP2007526291A (fr)
KR (1) KR20070004792A (fr)
AU (1) AU2005218997B2 (fr)
BR (1) BRPI0508488A (fr)
CA (1) CA2557285A1 (fr)
EA (2) EA014425B1 (fr)
MX (1) MXPA06010075A (fr)
NO (1) NO20064365L (fr)
SG (1) SG144146A1 (fr)
WO (1) WO2005084653A2 (fr)

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JP2007536241A (ja) * 2004-05-03 2007-12-13 ユニバーシティ オブ バージニア パテント ファウンデーション 糖尿病性腎症の処置のためのａ２ａアデノシンレセプターアゴニスト
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GB0500785D0 (en) 2005-01-14 2005-02-23 Novartis Ag Organic compounds
CN1947717B (zh) * 2005-10-14 2012-09-26 卓敏 选择性抑制腺苷酸环化酶1的化合物在制备用于治疗神经性疼痛和炎性疼痛的药物中的应用
US20070183995A1 (en) * 2006-02-09 2007-08-09 Conopco, Inc., D/B/A Unilever Compounds useful as agonists of A2A adenosine receptors, cosmetic compositions with A2A agonists and a method for using the same
WO2007120972A2 (fr) 2006-02-10 2007-10-25 University Of Virginia Patent Foundation Procede permettant de traiter l'anemie a hematies falciformes
ATE549337T1 (de) 2006-04-21 2012-03-15 Novartis Ag Purinderivate zur verwendung als adenosin-a2a- rezeptoragonisten
GB0607950D0 (en) 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
US8188063B2 (en) 2006-06-19 2012-05-29 University Of Virginia Patent Foundation Use of adenosine A2A modulators to treat spinal cord injury
CN101479290A (zh) * 2006-06-27 2009-07-08 比奥维特罗姆上市公司 新的2′,3′-亚甲基缩醛腺苷前药用作腺苷受体激动剂的前药
RU2009102536A (ru) 2006-06-27 2010-08-10 Биовитрум Аб (Пабл) (Se) Терапевтические соединения
AU2007263728A1 (en) * 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Adenosine derivatives for the treatment of pain
EP1889846A1 (fr) 2006-07-13 2008-02-20 Novartis AG Dérivés de purine comme agonistes du recepteur A2a
EP1903044A1 (fr) 2006-09-14 2008-03-26 Novartis AG Derivés de l'adénosine en tant qu' agonistes du récepteur A2A
WO2009061516A1 (fr) 2007-11-08 2009-05-14 New York University School Of Medicine Implants médicaux contenant des agonistes du récepteur de l'adénosine et procédés pour inhiber un relâchement d'implant médical
US8058259B2 (en) 2007-12-20 2011-11-15 University Of Virginia Patent Foundation Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists
WO2009089425A1 (fr) * 2008-01-09 2009-07-16 Pgxhealth Llc Traitement intrathécal d'une douleur neuropathique avec des agonistes a2ar
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071865A1 (fr) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Compositions pharmaceutiques et procédés de traitement de l'hyperuricémie et des troubles associés
WO2011004166A1 (fr) * 2009-07-09 2011-01-13 Cbt Development Limited Préparation combinée pour une utilisation en tant que médicament
WO2011032175A1 (fr) 2009-09-14 2011-03-17 Nuon Therapeutics, Inc. Formulations combinées de tranilast et d'allopurinol et procédés associées à celles-ci
WO2011069294A1 (fr) * 2009-12-10 2011-06-16 中国医学科学院药物研究所 Dérivés d'adénosine à substitution n6, dérivés d'adénine à substitution n6 et leurs utilisations
WO2011123518A1 (fr) * 2010-03-31 2011-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Agonistes de récepteur d'adénosine pour le traitement et la prévention de troubles de calcification de capsule vasculaire ou articulaire
CA2847540C (fr) * 2011-09-22 2016-05-17 Pfizer Inc. Derives de pyrrolopyrimidine et de purine
FR2981650B1 (fr) * 2011-10-24 2013-12-27 Univ Paris Curie Analogues de nucleosides pour le traitement d'une infection virale et methode d'evaluation de la sensibilite audit traitement
US20160038526A1 (en) * 2012-08-16 2016-02-11 Thomas Jefferson University Treatment of prostate cancer
US20150209379A1 (en) * 2012-08-16 2015-07-30 Thomas Jefferson University Treatment of prostate cancer and hematologic neoplasms
EP2711008A1 (fr) 2012-09-19 2014-03-26 Institut Univ. de Ciència i Tecnologia, S.A. N6,N6-dimethyladenosine destiné à être utilisé dans le traitement ou la prévention du cancer du sein primitif et métastatique
WO2015085497A1 (fr) * 2013-12-10 2015-06-18 Scinopharm Taiwan, Ltd. Procédé de préparation de régadénoson
EP3573996B1 (fr) * 2017-01-27 2022-06-15 Academia Sinica Composé à effet analgésique destiné à être utilisé dans la prévention et le traitement de la douleur

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AU2005218997B2 (en) 2012-05-10
EA200601642A1 (ru) 2006-12-29
JP2007526291A (ja) 2007-09-13
EA200800538A1 (ru) 2008-06-30
NO20064365L (no) 2006-11-22
EP1749016A2 (fr) 2007-02-07
CA2557285A1 (fr) 2005-09-15
US20080221060A1 (en) 2008-09-11
EA014425B1 (ru) 2010-12-30
WO2005084653A3 (fr) 2006-05-18
BRPI0508488A (pt) 2007-07-31
KR20070004792A (ko) 2007-01-09
MXPA06010075A (es) 2007-04-10
WO2005084653A2 (fr) 2005-09-15
AU2005218997A1 (en) 2005-09-15

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