SG11202112123RA - Methods of administering chimeric antigen receptor immunotherapy - Google Patents
Methods of administering chimeric antigen receptor immunotherapyInfo
- Publication number
- SG11202112123RA SG11202112123RA SG11202112123RA SG11202112123RA SG11202112123RA SG 11202112123R A SG11202112123R A SG 11202112123RA SG 11202112123R A SG11202112123R A SG 11202112123RA SG 11202112123R A SG11202112123R A SG 11202112123RA SG 11202112123R A SG11202112123R A SG 11202112123RA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- antigen receptor
- chimeric antigen
- administering chimeric
- immunotherapy
- Prior art date
Links
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C—CHEMISTRY; METALLURGY
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962843190P | 2019-05-03 | 2019-05-03 | |
US201962855828P | 2019-05-31 | 2019-05-31 | |
US201962868262P | 2019-06-28 | 2019-06-28 | |
US201962931669P | 2019-11-06 | 2019-11-06 | |
US201962944903P | 2019-12-06 | 2019-12-06 | |
PCT/US2020/031231 WO2020227177A1 (en) | 2019-05-03 | 2020-05-03 | Methods of administering chimeric antigen receptor immunotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202112123RA true SG11202112123RA (en) | 2021-11-29 |
Family
ID=73050885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202112123RA SG11202112123RA (en) | 2019-05-03 | 2020-05-03 | Methods of administering chimeric antigen receptor immunotherapy |
Country Status (13)
Country | Link |
---|---|
US (2) | US20200384027A1 (pt) |
EP (2) | EP3962490A4 (pt) |
JP (1) | JP2022532865A (pt) |
KR (1) | KR20220005075A (pt) |
CN (1) | CN114206346A (pt) |
AU (1) | AU2020267378A1 (pt) |
BR (1) | BR112021021996A2 (pt) |
CA (1) | CA3138707A1 (pt) |
IL (1) | IL287533A (pt) |
MX (1) | MX2021013394A (pt) |
SG (1) | SG11202112123RA (pt) |
TW (1) | TW202108150A (pt) |
WO (1) | WO2020227177A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022117799A2 (en) * | 2020-12-04 | 2022-06-09 | Morphosys Ag | Anti-cd19 combination therapy |
US20220202859A1 (en) * | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Cancer treatment using cd38 inhibitor and/or lenalidomide and t-cells expressing a chimeric antigen receptor |
TW202242117A (zh) | 2020-12-30 | 2022-11-01 | 美商亞勞諾斯醫療公司 | 包含多順反子表現卡匣之重組載體及其使用方法 |
CN113406334A (zh) * | 2021-06-02 | 2021-09-17 | 浙江省人民医院 | 一种dlbcl相关的生物标记组合物及其应用、dlbcl预后的效果预测模型 |
AU2022317827A1 (en) * | 2021-07-30 | 2024-01-25 | Kite Pharma, Inc. | Monitoring and management of cell therapy-induced toxicities |
CN113786490A (zh) * | 2021-09-14 | 2021-12-14 | 华中科技大学同济医学院附属协和医院 | 能调控巨噬细胞表观遗传的制剂用于制备治疗噬血细胞综合征药物的应用 |
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MXPA02008265A (es) | 2000-02-24 | 2004-09-10 | Xcyte Therapies Inc | Concentracion y estimulacion simultanea de calulas. |
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TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
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BR122021026169B1 (pt) | 2010-12-09 | 2023-12-12 | The Trustees Of The University Of Pennsylvania | Uso de uma célula |
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EP2532740A1 (en) | 2011-06-11 | 2012-12-12 | Michael Schmück | Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy |
AU2012308205A1 (en) | 2011-09-16 | 2014-03-13 | The Trustees Of The University Of Pennsylvania | RNA engineered T cells for the treatment of cancer |
WO2014055657A1 (en) | 2012-10-05 | 2014-04-10 | The Trustees Of The University Of Pennsylvania | Use of a trans-signaling approach in chimeric antigen receptors |
EP3102609A4 (en) | 2014-02-04 | 2017-08-23 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Methods for producing autologous t cells useful to treat b cell malignancies and other cancers and compositions thereof |
KR20220008388A (ko) | 2015-05-28 | 2022-01-20 | 카이트 파마 인코포레이티드 | T 세포 요법을 위해 환자를 컨디셔닝하는 방법 |
AU2016341966A1 (en) | 2015-10-20 | 2018-05-10 | Kite Pharma, Inc. | Methods of preparing T cells for T cell therapy |
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EP3484455A2 (en) * | 2016-07-15 | 2019-05-22 | Novartis AG | Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor |
JOP20180042A1 (ar) * | 2017-04-24 | 2019-01-30 | Kite Pharma Inc | نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام |
AU2018275894A1 (en) * | 2017-06-02 | 2019-12-12 | Juno Therapeutics, Inc. | Articles of manufacture and methods for treatment using adoptive cell therapy |
WO2019070680A2 (en) * | 2017-10-02 | 2019-04-11 | Humanigen, Inc. | METHODS OF TREATING IMMUNOTHERAPY-RELATED TOXICITY USING GM-CSF ANTAGONIST |
AR113777A1 (es) * | 2017-10-18 | 2020-06-10 | Kite Pharma Inc | Métodos de administración de una inmunoterapia con receptores de antígenos quiméricos |
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2020
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- 2020-05-03 JP JP2021564704A patent/JP2022532865A/ja active Pending
- 2020-05-03 KR KR1020217039585A patent/KR20220005075A/ko active Search and Examination
- 2020-05-03 SG SG11202112123RA patent/SG11202112123RA/en unknown
- 2020-05-03 WO PCT/US2020/031231 patent/WO2020227177A1/en unknown
- 2020-05-03 BR BR112021021996A patent/BR112021021996A2/pt unknown
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- 2020-05-03 MX MX2021013394A patent/MX2021013394A/es unknown
- 2020-05-03 EP EP20801592.5A patent/EP3962490A4/en not_active Withdrawn
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CN114206346A (zh) | 2022-03-18 |
AU2020267378A1 (en) | 2021-11-25 |
US20200384027A1 (en) | 2020-12-10 |
EP3962490A4 (en) | 2023-01-25 |
MX2021013394A (es) | 2022-01-04 |
KR20220005075A (ko) | 2022-01-12 |
EP3962490A1 (en) | 2022-03-09 |
US20230270785A1 (en) | 2023-08-31 |
JP2022532865A (ja) | 2022-07-20 |
WO2020227177A1 (en) | 2020-11-12 |
BR112021021996A2 (pt) | 2022-01-11 |
EP4249075A2 (en) | 2023-09-27 |
TW202108150A (zh) | 2021-03-01 |
CA3138707A1 (en) | 2020-11-12 |
IL287533A (en) | 2021-12-01 |
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