SG11202111462VA - Asx-specific protein ligases and uses thereof - Google Patents

Asx-specific protein ligases and uses thereof

Info

Publication number
SG11202111462VA
SG11202111462VA SG11202111462VA SG11202111462VA SG11202111462VA SG 11202111462V A SG11202111462V A SG 11202111462VA SG 11202111462V A SG11202111462V A SG 11202111462VA SG 11202111462V A SG11202111462V A SG 11202111462VA SG 11202111462V A SG11202111462V A SG 11202111462VA
Authority
SG
Singapore
Prior art keywords
asx
specific protein
protein ligases
ligases
specific
Prior art date
Application number
SG11202111462VA
Other languages
English (en)
Inventor
James P Tam
Julien Lescar
Muxinya He
Sahili Abbas El
Chuan Fa Liu
Side Hu
Original Assignee
Univ Nanyang Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nanyang Tech filed Critical Univ Nanyang Tech
Publication of SG11202111462VA publication Critical patent/SG11202111462VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
SG11202111462VA 2019-05-07 2020-05-06 Asx-specific protein ligases and uses thereof SG11202111462VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201904085W 2019-05-07
SG10201910861S 2019-11-19
PCT/SG2020/050267 WO2020226572A1 (en) 2019-05-07 2020-05-06 Asx-specific protein ligases and uses thereof

Publications (1)

Publication Number Publication Date
SG11202111462VA true SG11202111462VA (en) 2021-11-29

Family

ID=73051360

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202111462VA SG11202111462VA (en) 2019-05-07 2020-05-06 Asx-specific protein ligases and uses thereof

Country Status (7)

Country Link
US (1) US20220213461A1 (ja)
EP (1) EP3966321A4 (ja)
JP (1) JP2022533545A (ja)
KR (1) KR20220005566A (ja)
CN (1) CN113811606A (ja)
SG (1) SG11202111462VA (ja)
WO (1) WO2020226572A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240117402A1 (en) * 2021-02-10 2024-04-11 Nanyang Technological University Methods for (poly) peptide tandem ligation and cyclization
WO2023191726A1 (en) * 2022-03-31 2023-10-05 Nanyang Technological University Improving the efficiency of pal-catalyzed protein ligation by a cascade enzymatic scheme

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7835198A (en) * 1997-06-12 1998-12-30 E.I. Du Pont De Nemours And Company Plant amino acid biosynthetic enzymes
EP2851424B1 (en) * 2007-03-09 2016-09-21 Novozymes A/S Thermostable asparaginases
CN106459160B (zh) * 2014-04-24 2022-03-29 南洋理工大学 Asx特异性蛋白质连接酶
EP3353315A4 (en) * 2015-09-25 2019-10-16 Hexima Limited PEPTIDE PRODUCTION

Also Published As

Publication number Publication date
EP3966321A1 (en) 2022-03-16
CN113811606A (zh) 2021-12-17
US20220213461A1 (en) 2022-07-07
EP3966321A4 (en) 2023-09-06
JP2022533545A (ja) 2022-07-25
WO2020226572A1 (en) 2020-11-12
KR20220005566A (ko) 2022-01-13

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