SG11202109160UA - Reducing intersample analyte variability in complex biological matrices - Google Patents

Reducing intersample analyte variability in complex biological matrices

Info

Publication number
SG11202109160UA
SG11202109160UA SG11202109160UA SG11202109160UA SG 11202109160U A SG11202109160U A SG 11202109160UA SG 11202109160U A SG11202109160U A SG 11202109160UA SG 11202109160U A SG11202109160U A SG 11202109160UA
Authority
SG
Singapore
Prior art keywords
intersample
reducing
complex biological
biological matrices
analyte variability
Prior art date
Application number
Other languages
English (en)
Inventor
Daniel Drolet
David Astling
Carlowitz Ira Von
Thomas Howard Hraha
Jan Hoh
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of SG11202109160UA publication Critical patent/SG11202109160UA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827—Total protein determination, e.g. albumin in urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/075—Investigating concentration of particle suspensions by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
SG11202109160U 2019-03-22 2020-03-20 Reducing intersample analyte variability in complex biological matrices SG11202109160UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962822349P 2019-03-22 2019-03-22
PCT/US2020/023866 WO2020198011A1 (fr) 2019-03-22 2020-03-20 Réduction de la variabilité d'analytes inter-échantillons dans des matrices biologiques complexes

Publications (1)

Publication Number Publication Date
SG11202109160UA true SG11202109160UA (en) 2021-10-28

Family

ID=70228886

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202109160U SG11202109160UA (en) 2019-03-22 2020-03-20 Reducing intersample analyte variability in complex biological matrices

Country Status (10)

Country Link
US (1) US20220178940A1 (fr)
EP (1) EP3942295A1 (fr)
JP (1) JP2022524975A (fr)
KR (1) KR20210142694A (fr)
CN (1) CN113508297A (fr)
AU (1) AU2020245346A1 (fr)
CA (1) CA3134336A1 (fr)
IL (1) IL286495A (fr)
SG (1) SG11202109160UA (fr)
WO (1) WO2020198011A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11728147B2 (en) * 2020-10-20 2023-08-15 Definitek, Inc. Quantification of previously undetectable quantities
CN112666356A (zh) * 2020-12-31 2021-04-16 国家纳米科学中心 一种检测痕量蛋白质的方法
CN116899626B (zh) * 2023-09-08 2023-12-26 北京青颜博识健康管理有限公司 一种点击化学反应的催化体系组合物及其制备方法和在生物检测中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970002255B1 (ko) 1990-06-11 1997-02-26 넥스스타 파아마슈티컬드, 인크. 핵산 리간드
US5719273A (en) 1993-06-14 1998-02-17 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
US5945527A (en) 1996-05-30 1999-08-31 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modification methods using nucleophiles and carbon monoxide
US6242246B1 (en) 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
EP3345915B1 (fr) 2010-04-12 2021-11-24 Somalogic, Inc. Pyramidines modifiés en position 5 et leur utilisation

Also Published As

Publication number Publication date
KR20210142694A (ko) 2021-11-25
AU2020245346A1 (en) 2021-09-09
US20220178940A1 (en) 2022-06-09
JP2022524975A (ja) 2022-05-11
CA3134336A1 (fr) 2020-10-01
WO2020198011A1 (fr) 2020-10-01
CN113508297A (zh) 2021-10-15
IL286495A (en) 2021-10-31
EP3942295A1 (fr) 2022-01-26

Similar Documents

Publication Publication Date Title
IL286495A (en) Reducing inter-sample analysis variability in complex biological matrices
EP3371194A4 (fr) Procédés et réactifs de séquençage de protéines
EP3735481A4 (fr) Procédés de fabrication d'une puce à adn à haute résolution et utilisation de celle-ci dans le séquençage
IL288014A (en) Controlling inter-sample test substance variability in complex biological matrices
HK1254396A1 (zh) 一種dna片段體外組裝方法和試劑盒
IL287318A (en) Materials and methods for the production of proteins
GB201813449D0 (en) Skin cell analysis
EP3815094A4 (fr) Analyse d'intégration et de réarrangement d'acides nucléiques
EP3880151A4 (fr) Détermination de la réponse de traitement dans des cellules uniques
IL268330A (en) Methods for determining interaction between biological cells
IL261835A (en) Analytical methods and arrays for their use
SG11202108157WA (en) Biological analysis system and methods
EP3527669A4 (fr) Kit d'analyse quantitative de l'hémoglobine a1c
IL281796A (en) Quantification of antibody in biological samples
GB201913908D0 (en) Improvements in interaction analysis
SG11202110398QA (en) Concurrent analysis of multiple analytes
EP3891301A4 (fr) Quantification d'adn étranger dans des échantillons de sang à faible volume à l'aide d'un profilage snp
SG11202102265UA (en) Hemoglobin assay reagent, assay kit and assay method
GB2579810B (en) Assay Analysis
EP3610012A4 (fr) Mesures d'absorbance à haut débit d'échantillons dans des réseaux microcapillaires
IL278937A (en) HSP70 protein levels in PBMC samples as a disease biomarker
EP3814500A4 (fr) Procédés d'analyse de l'adn dans l'urine
GB201710524D0 (en) Controlling intersample analyte variability in complex biological matrices
IL281658A (en) Nucleic acids for cell recognition and integration
DK3615689T3 (en) Analytical methods and arrays for use in the same