SG11202108867VA - Pharmaceutical composition comprising flt3 inhibitor and hypomethylating agent for treating acute myeloid leukemia - Google Patents

Pharmaceutical composition comprising flt3 inhibitor and hypomethylating agent for treating acute myeloid leukemia

Info

Publication number
SG11202108867VA
SG11202108867VA SG11202108867VA SG11202108867VA SG11202108867VA SG 11202108867V A SG11202108867V A SG 11202108867VA SG 11202108867V A SG11202108867V A SG 11202108867VA SG 11202108867V A SG11202108867V A SG 11202108867VA SG 11202108867V A SG11202108867V A SG 11202108867VA
Authority
SG
Singapore
Prior art keywords
pharmaceutical composition
myeloid leukemia
acute myeloid
treating acute
flt3 inhibitor
Prior art date
Application number
SG11202108867VA
Other languages
English (en)
Inventor
In Hwan Bae
Ji Sook Kim
Jae Yul Choi
Young Gil Ahn
Original Assignee
Hanmi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharmaceutical Co Ltd filed Critical Hanmi Pharmaceutical Co Ltd
Priority claimed from PCT/KR2020/002536 external-priority patent/WO2020171646A1/ko
Publication of SG11202108867VA publication Critical patent/SG11202108867VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202108867VA 2019-02-22 2020-02-21 Pharmaceutical composition comprising flt3 inhibitor and hypomethylating agent for treating acute myeloid leukemia SG11202108867VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20190021228 2019-02-22
KR1020200021502A KR20200102949A (ko) 2019-02-22 2020-02-21 Flt3 저해제 및 저메틸화제를 포함하는 급성 골수성 백혈병의 치료를 위한 약학적 조성물
PCT/KR2020/002536 WO2020171646A1 (ko) 2019-02-22 2020-02-21 Flt3 저해제 및 저메틸화제를 포함하는 급성 골수성 백혈병의 치료를 위한 약학적 조성물

Publications (1)

Publication Number Publication Date
SG11202108867VA true SG11202108867VA (en) 2021-09-29

Family

ID=72470030

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108867VA SG11202108867VA (en) 2019-02-22 2020-02-21 Pharmaceutical composition comprising flt3 inhibitor and hypomethylating agent for treating acute myeloid leukemia

Country Status (8)

Country Link
EP (1) EP3928780A4 (ru)
KR (1) KR20200102949A (ru)
CN (1) CN113490497A (ru)
AU (1) AU2020226111A1 (ru)
CA (1) CA3130244A1 (ru)
EA (1) EA202191984A1 (ru)
IL (1) IL285628A (ru)
SG (1) SG11202108867VA (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114650823A (zh) * 2019-06-27 2022-06-21 韩美药品株式会社 用于治疗急性髓系白血病的含有flt3抑制剂和化疗剂的药物组合物
EP4370127A2 (en) * 2021-07-12 2024-05-22 Quteba Ebrahem A method of treating cancer or a blood disorder

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009005621A (es) 2006-11-28 2009-06-12 Novartis Ag Combinacion de inhibidores de iap e inhibidores de flt3.
KR20180124055A (ko) 2016-03-29 2018-11-20 아스테라스 세이야쿠 가부시키가이샤 급성 골수성 백혈병의 치료를 위한 병용 요법
PT3514153T (pt) * 2017-01-26 2021-09-22 Hanmi Pharm Ind Co Ltd Composto de pirimidina e utilização farmacêutica do mesmo

Also Published As

Publication number Publication date
KR20200102949A (ko) 2020-09-01
EP3928780A4 (en) 2022-12-07
CN113490497A (zh) 2021-10-08
AU2020226111A1 (en) 2021-09-09
EP3928780A1 (en) 2021-12-29
EA202191984A1 (ru) 2021-11-19
IL285628A (en) 2021-09-30
CA3130244A1 (en) 2020-08-27

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