SG11202108160YA - Sulcardine salts - Google Patents

Sulcardine salts

Info

Publication number
SG11202108160YA
SG11202108160YA SG11202108160YA SG11202108160YA SG11202108160YA SG 11202108160Y A SG11202108160Y A SG 11202108160YA SG 11202108160Y A SG11202108160Y A SG 11202108160YA SG 11202108160Y A SG11202108160Y A SG 11202108160YA SG 11202108160Y A SG11202108160Y A SG 11202108160YA
Authority
SG
Singapore
Prior art keywords
sulcardine
salts
sulcardine salts
Prior art date
Application number
SG11202108160YA
Other languages
English (en)
Inventor
Suzanne Romano
Hayley Reece
Joseph Benson
Sarah Collins
Gary T Elliott
Mireille Gillings
Robert Goodenow
Curtis Tyree
Original Assignee
Huya Bioscience International Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huya Bioscience International Llc filed Critical Huya Bioscience International Llc
Publication of SG11202108160YA publication Critical patent/SG11202108160YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42Separation; Purification; Stabilisation; Use of additives
    • C07C303/44Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/05Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing at least two sulfo groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Inorganic Chemistry (AREA)
SG11202108160YA 2019-01-29 2020-01-28 Sulcardine salts SG11202108160YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962798467P 2019-01-29 2019-01-29
US202062959687P 2020-01-10 2020-01-10
PCT/US2020/015370 WO2020159959A1 (fr) 2019-01-29 2020-01-28 Sels de sulcardine

Publications (1)

Publication Number Publication Date
SG11202108160YA true SG11202108160YA (en) 2021-08-30

Family

ID=69724142

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108160YA SG11202108160YA (en) 2019-01-29 2020-01-28 Sulcardine salts

Country Status (15)

Country Link
US (3) US11426382B2 (fr)
EP (1) EP3917921A1 (fr)
JP (2) JP2022518906A (fr)
KR (2) KR102405199B1 (fr)
CN (2) CN115385871A (fr)
AU (1) AU2020216925B2 (fr)
BR (1) BR112021014640A8 (fr)
CA (1) CA3128152A1 (fr)
CL (1) CL2021001968A1 (fr)
CO (1) CO2021011042A2 (fr)
IL (1) IL285184B2 (fr)
MX (1) MX2021009033A (fr)
SG (1) SG11202108160YA (fr)
WO (1) WO2020159959A1 (fr)
ZA (2) ZA202105344B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3123078A1 (fr) 2018-12-13 2020-06-18 Huya Bioscience International, Llc Administration de sulcardine pour le traitement d'une fibrillation atriale aigue
CA3128152A1 (fr) 2019-01-29 2020-08-06 Huya Bioscience International, Llc Sels de sulcardine
KR20230024347A (ko) 2020-06-12 2023-02-20 후야바이오 인터내셔널, 엘엘씨 급성 심방 세동의 치료를 위한 설카르딘 투여

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1172908C (zh) 1999-12-10 2004-10-27 中国科学院上海药物研究所 N-取代苄基或苯基芳香磺酰胺化合物及其用途
CN1299813C (zh) 2004-12-28 2007-02-14 华南理工大学 自动撕膜落料及多样性搅拌的机构和控制装置
CN1939298A (zh) 2005-09-29 2007-04-04 中国科学院上海药物研究所 硫酸舒欣啶固体和靶向制剂及其制备方法
JP6116907B2 (ja) * 2009-11-17 2017-04-19 フヤ バイオサイエンス インターナショナル エルエルシー サルカルディン及びその塩の緩速点滴
JP6116908B2 (ja) * 2009-11-17 2017-04-19 フヤ バイオサイエンス インターナショナル エルエルシー 心房細動の治療
MA41599A (fr) * 2015-02-26 2018-01-02 Array Biopharma Inc Formes cristallines d'un composé pyrrolopyridine
AU2016272089B2 (en) 2015-06-03 2021-02-18 Triastek, Inc. Dosage forms and use thereof
KR101965283B1 (ko) 2016-05-05 2019-04-03 트리아스텍 인코포레이티드 제어 방출 제형
KR20190107712A (ko) 2017-01-26 2019-09-20 트리아스텍 인코포레이티드 특정 위장 부위에서의 제어 방출의 투여 형태
AR110998A1 (es) * 2017-02-24 2019-05-22 Gilead Sciences Inc Inhibidores de la tirosina cinasa de bruton
CA3123078A1 (fr) 2018-12-13 2020-06-18 Huya Bioscience International, Llc Administration de sulcardine pour le traitement d'une fibrillation atriale aigue
CA3128152A1 (fr) 2019-01-29 2020-08-06 Huya Bioscience International, Llc Sels de sulcardine

Also Published As

Publication number Publication date
US20220356319A1 (en) 2022-11-10
US11020374B2 (en) 2021-06-01
KR102405199B1 (ko) 2022-06-02
BR112021014640A8 (pt) 2022-12-20
BR112021014640A2 (pt) 2021-09-21
AU2020216925B2 (en) 2022-09-15
US20200316024A1 (en) 2020-10-08
ZA202105344B (en) 2023-01-25
CA3128152A1 (fr) 2020-08-06
ZA202107474B (en) 2022-06-29
IL285184B1 (en) 2023-08-01
CL2021001968A1 (es) 2022-01-28
JP2024039020A (ja) 2024-03-21
CO2021011042A2 (es) 2022-01-17
IL285184B2 (en) 2023-12-01
KR20220079688A (ko) 2022-06-13
CN115385871A (zh) 2022-11-25
US20210038568A1 (en) 2021-02-11
WO2020159959A1 (fr) 2020-08-06
KR20210130157A (ko) 2021-10-29
IL285184A (en) 2021-09-30
CN112638903A (zh) 2021-04-09
AU2020216925A1 (en) 2021-09-02
CN112638903B (zh) 2022-08-26
JP2022518906A (ja) 2022-03-17
EP3917921A1 (fr) 2021-12-08
US11426382B2 (en) 2022-08-30
MX2021009033A (es) 2021-10-13

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