SG11202101085PA - Optically active azabicyclic derivative - Google Patents
Optically active azabicyclic derivativeInfo
- Publication number
- SG11202101085PA SG11202101085PA SG11202101085PA SG11202101085PA SG11202101085PA SG 11202101085P A SG11202101085P A SG 11202101085PA SG 11202101085P A SG11202101085P A SG 11202101085PA SG 11202101085P A SG11202101085P A SG 11202101085PA SG 11202101085P A SG11202101085P A SG 11202101085PA
- Authority
- SG
- Singapore
- Prior art keywords
- optically active
- azabicyclic derivative
- derivative
- active azabicyclic
- optically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018158315 | 2018-08-27 | ||
| PCT/JP2019/033234 WO2020045334A1 (ja) | 2018-08-27 | 2019-08-26 | 光学活性なアザビシクロ環誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202101085PA true SG11202101085PA (en) | 2021-03-30 |
Family
ID=69644540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202101085PA SG11202101085PA (en) | 2018-08-27 | 2019-08-26 | Optically active azabicyclic derivative |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11369605B2 (ja) |
| EP (1) | EP3845533A4 (ja) |
| JP (3) | JP6671574B1 (ja) |
| KR (1) | KR20210049136A (ja) |
| CN (1) | CN112585140B (ja) |
| AU (1) | AU2019327006B2 (ja) |
| BR (1) | BR112021002090A8 (ja) |
| CA (1) | CA3107743A1 (ja) |
| EA (1) | EA202190623A1 (ja) |
| MX (1) | MX2021002424A (ja) |
| PH (1) | PH12021550229A1 (ja) |
| SG (1) | SG11202101085PA (ja) |
| TW (1) | TWI815954B (ja) |
| WO (1) | WO2020045334A1 (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3835304A4 (en) * | 2018-08-08 | 2022-06-08 | Sumitomo Dainippon Pharma Co., Ltd. | OPTICALLY ACTIVE BRIDGED PIPERIDINE DERIVATIVE |
| EA202190623A1 (ru) * | 2018-08-27 | 2021-05-21 | Сумитомо Дайниппон Фарма Ко., Лтд. | Оптически активное азабициклическое производное |
| WO2021060453A1 (ja) * | 2019-09-27 | 2021-04-01 | 大日本住友製薬株式会社 | 架橋型光学活性２級アミン誘導体 |
| JP7454520B2 (ja) | 2020-02-26 | 2024-03-22 | 住友ファーマ株式会社 | 光学活性なアザビシクロ環誘導体からなる医薬 |
| WO2022130270A1 (en) | 2020-12-17 | 2022-06-23 | Astrazeneca Ab | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)- quinoline-4-carboxamides |
| WO2022237626A1 (en) | 2021-05-08 | 2022-11-17 | Janssen Pharmaceutica Nv | Substituted spiro derivatives |
| EP4334320A1 (en) | 2021-05-08 | 2024-03-13 | JANSSEN Pharmaceutica NV | Substituted spiro derivatives |
| EP4271676A1 (en) * | 2021-12-03 | 2023-11-08 | Bionova Pharmaceuticals (Shanghai) Limited | Carbonyl substituted diazaspiro compounds and its use |
| WO2024110649A1 (en) | 2022-11-24 | 2024-05-30 | Oryzon Genomics, S.A. | Combinations of lsd1 inhibitors and menin inhibitors for treating cancer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6583148B1 (en) | 1999-04-08 | 2003-06-24 | Krenitsky Pharmaceuticals, Inc. | Neurotrophic substituted pyrimidines |
| AR039208A1 (es) | 2002-04-03 | 2005-02-09 | Syngenta Participations Ag | Compuestos de fenil- y piridilalquinos, composicion herbicida que los contiene, procedimiento de preparacion de aquellos y procedimiento para combatir el crecimiento de plantas indeseadas |
| TW200528440A (en) | 2003-10-31 | 2005-09-01 | Fujisawa Pharmaceutical Co | 2-cyanopyrrolidinecarboxamide compound |
| CL2008000197A1 (es) | 2007-01-26 | 2008-08-01 | Smithkline Beecham Corp | Compuestos derivados de 2,4-diamino pirimidina, inhibidores de antranilamida de cinasa aurora; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar cancer. |
| US20090281114A1 (en) | 2008-05-08 | 2009-11-12 | Fabre-Kramer Pharmaceuticals, Inc. | Indolylalkyl derivatives of pyrimidinylpiperazine and metabolites thereof for treatment of anxiety, depression, and sexual dysfunction |
| SG11201609336PA (en) | 2014-05-13 | 2016-12-29 | Sloan Kettering Inst Cancer | Hsp70 modulators and methods for making and using the same |
| KR20180103053A (ko) | 2015-12-22 | 2018-09-18 | 비타이 파마슈티컬즈, 인코포레이티드 | 메닌-mll 상호작용의 억제제 |
| CN109743875B (zh) * | 2016-06-10 | 2022-04-29 | 生命医药有限责任公司 | Menin-mll相互作用的抑制剂 |
| EP3512858B1 (en) | 2016-09-14 | 2023-11-08 | Janssen Pharmaceutica NV | Fused bicyclic inhibitors of menin-mll interaction |
| WO2018050686A1 (en) * | 2016-09-14 | 2018-03-22 | Janssen Pharmaceutica Nv | Spiro bicyclic inhibitors of menin-mll interaction |
| BR112019005030A2 (pt) * | 2016-09-16 | 2019-06-18 | Vitae Pharmaceuticals Inc | inibidores da interação de menina-llm |
| EP3562823B1 (en) * | 2016-12-28 | 2023-02-08 | Promega Corporation | Functionalized nanoluc inhibitors |
| CN112105621B (zh) * | 2018-03-30 | 2024-02-20 | 住友制药株式会社 | 光学活性桥型环状仲胺衍生物 |
| US10815241B2 (en) * | 2018-08-27 | 2020-10-27 | Sumitomo Dainippon Pharma Co., Ltd. | Optically active azabicyclo ring derivative |
| EA202190623A1 (ru) * | 2018-08-27 | 2021-05-21 | Сумитомо Дайниппон Фарма Ко., Лтд. | Оптически активное азабициклическое производное |
-
2019
- 2019-08-26 EA EA202190623A patent/EA202190623A1/ru unknown
- 2019-08-26 AU AU2019327006A patent/AU2019327006B2/en active Active
- 2019-08-26 SG SG11202101085PA patent/SG11202101085PA/en unknown
- 2019-08-26 CA CA3107743A patent/CA3107743A1/en active Pending
- 2019-08-26 JP JP2019572251A patent/JP6671574B1/ja active Active
- 2019-08-26 TW TW108130415A patent/TWI815954B/zh active
- 2019-08-26 WO PCT/JP2019/033234 patent/WO2020045334A1/ja active Application Filing
- 2019-08-26 MX MX2021002424A patent/MX2021002424A/es unknown
- 2019-08-26 US US16/629,739 patent/US11369605B2/en active Active
- 2019-08-26 KR KR1020217008548A patent/KR20210049136A/ko unknown
- 2019-08-26 CN CN201980056344.5A patent/CN112585140B/zh active Active
- 2019-08-26 EP EP19854536.0A patent/EP3845533A4/en active Pending
- 2019-08-26 BR BR112021002090A patent/BR112021002090A8/pt unknown
-
2020
- 2020-03-03 JP JP2020035812A patent/JP7317749B2/ja active Active
-
2021
- 2021-01-29 PH PH12021550229A patent/PH12021550229A1/en unknown
-
2022
- 2022-05-23 US US17/750,721 patent/US11911381B2/en active Active
-
2023
- 2023-07-19 JP JP2023117267A patent/JP2023134729A/ja active Pending
-
2024
- 2024-01-12 US US18/412,308 patent/US20240148727A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11911381B2 (en) | 2024-02-27 |
| US20220288072A1 (en) | 2022-09-15 |
| AU2019327006A1 (en) | 2021-03-04 |
| CN112585140B (zh) | 2023-07-04 |
| PH12021550229A1 (en) | 2021-10-11 |
| AU2019327006B2 (en) | 2024-02-15 |
| US20240148727A1 (en) | 2024-05-09 |
| CA3107743A1 (en) | 2020-03-05 |
| US11369605B2 (en) | 2022-06-28 |
| WO2020045334A1 (ja) | 2020-03-05 |
| JPWO2020045334A1 (ja) | 2020-09-03 |
| EP3845533A4 (en) | 2022-04-27 |
| TW202024082A (zh) | 2020-07-01 |
| TWI815954B (zh) | 2023-09-21 |
| CN112585140A (zh) | 2021-03-30 |
| JP2023134729A (ja) | 2023-09-27 |
| BR112021002090A2 (pt) | 2021-05-04 |
| KR20210049136A (ko) | 2021-05-04 |
| BR112021002090A8 (pt) | 2022-12-06 |
| JP2020105191A (ja) | 2020-07-09 |
| JP6671574B1 (ja) | 2020-03-25 |
| EP3845533A1 (en) | 2021-07-07 |
| MX2021002424A (es) | 2021-04-28 |
| JP7317749B2 (ja) | 2023-07-31 |
| US20210338668A1 (en) | 2021-11-04 |
| EA202190623A1 (ru) | 2021-05-21 |
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