SG11202100518TA - A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis - Google Patents

A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis

Info

Publication number
SG11202100518TA
SG11202100518TA SG11202100518TA SG11202100518TA SG11202100518TA SG 11202100518T A SG11202100518T A SG 11202100518TA SG 11202100518T A SG11202100518T A SG 11202100518TA SG 11202100518T A SG11202100518T A SG 11202100518TA SG 11202100518T A SG11202100518T A SG 11202100518TA
Authority
SG
Singapore
Prior art keywords
prevention
treatment
multiple sclerosis
substituted amino
pyrimidine compound
Prior art date
Application number
SG11202100518TA
Other languages
English (en)
Inventor
Martin Dyroff
David Mitchell
Orestis Papasouliotis
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG11202100518TA publication Critical patent/SG11202100518TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
SG11202100518TA 2018-07-20 2019-07-19 A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis SG11202100518TA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862700977P 2018-07-20 2018-07-20
US201862730184P 2018-09-12 2018-09-12
US201962839273P 2019-04-26 2019-04-26
PCT/IB2019/056198 WO2020016850A1 (en) 2018-07-20 2019-07-19 A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis

Publications (1)

Publication Number Publication Date
SG11202100518TA true SG11202100518TA (en) 2021-02-25

Family

ID=67953828

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100518TA SG11202100518TA (en) 2018-07-20 2019-07-19 A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis

Country Status (14)

Country Link
US (1) US20210260060A1 (ja)
EP (1) EP3823623A1 (ja)
JP (1) JP2021532104A (ja)
KR (1) KR20210034623A (ja)
CN (1) CN112437665A (ja)
AU (1) AU2019306828A1 (ja)
BR (1) BR112021000893A2 (ja)
CA (1) CA3106772A1 (ja)
IL (1) IL280197A (ja)
MX (1) MX2021000094A (ja)
SG (1) SG11202100518TA (ja)
TW (1) TW202019425A (ja)
UA (1) UA127744C2 (ja)
WO (1) WO2020016850A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3217452A1 (en) 2021-05-14 2022-11-17 David Andrew Coates Cocrystalline forms of a bruton's tyrosine kinase inhibitor
WO2023285696A1 (en) * 2021-07-15 2023-01-19 Sandoz Ag Mandelate form of 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one
WO2023247774A1 (en) 2022-06-24 2023-12-28 Merck Patent Gmbh Treatment regimen for autoimmune diseases and inflammatory diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10060388A1 (de) * 2000-12-05 2002-06-06 Merck Patent Gmbh Verwendung von Pyrazolo [4,3-d]pyrimidinen
WO2011156900A2 (en) * 2010-06-17 2011-12-22 Waratah Pharmaceuticals Inc. Compounds, compositions and methods for treatment of multiple sclerosis
JP2014517016A (ja) * 2011-06-10 2014-07-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Btk阻害活性を有するピリミジンおよびピリミジン化合物の組成物と製造方法
AU2013207972B2 (en) * 2012-01-10 2017-06-15 Nimbus Iris, Inc. IRAK inhibitors and uses thereof
TW201347762A (zh) * 2012-05-02 2013-12-01 Teva Pharma 高劑量拉喹莫德(laquinimod)於治療多發性硬化症之用途
BR112018007517B1 (pt) 2015-11-17 2023-09-26 Merck Patent Gmbh Uso decompostos de pirimidina e piridina com atividade inibidora de btk para preparar medicamentos para tratar esclerose múltipla
US10464923B2 (en) * 2017-02-27 2019-11-05 Merck Patent Gmbh Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone

Also Published As

Publication number Publication date
MX2021000094A (es) 2021-03-25
TW202019425A (zh) 2020-06-01
CA3106772A1 (en) 2020-01-23
US20210260060A1 (en) 2021-08-26
EP3823623A1 (en) 2021-05-26
IL280197A (en) 2021-03-01
UA127744C2 (uk) 2023-12-20
WO2020016850A1 (en) 2020-01-23
KR20210034623A (ko) 2021-03-30
CN112437665A (zh) 2021-03-02
BR112021000893A2 (pt) 2021-04-13
JP2021532104A (ja) 2021-11-25
AU2019306828A1 (en) 2021-03-11

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