SG11202011806WA - Method for the in vitro differentiation and maturation of dendritic cells for therapeutic use - Google Patents
Method for the in vitro differentiation and maturation of dendritic cells for therapeutic useInfo
- Publication number
- SG11202011806WA SG11202011806WA SG11202011806WA SG11202011806WA SG11202011806WA SG 11202011806W A SG11202011806W A SG 11202011806WA SG 11202011806W A SG11202011806W A SG 11202011806WA SG 11202011806W A SG11202011806W A SG 11202011806WA SG 11202011806W A SG11202011806W A SG 11202011806WA
- Authority
- SG
- Singapore
- Prior art keywords
- maturation
- dendritic cells
- therapeutic use
- vitro differentiation
- differentiation
- Prior art date
Links
- 210000004443 dendritic cell Anatomy 0.000 title 1
- 230000004069 differentiation Effects 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 230000035800 maturation Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001191—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/46449—Melanoma antigens
- A61K39/464491—Melan-A/MART
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/99—Serum-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/05—Adjuvants
- C12N2501/051—Lipid A (MPA, MPL)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2304—Interleukin-4 (IL-4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18179073 | 2018-06-21 | ||
PCT/EP2019/066398 WO2019243537A1 (fr) | 2018-06-21 | 2019-06-20 | Procédé de différenciation et de maturation in vitro de cellules dendritiques à usage thérapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202011806WA true SG11202011806WA (en) | 2021-01-28 |
Family
ID=62748830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202011806WA SG11202011806WA (en) | 2018-06-21 | 2019-06-20 | Method for the in vitro differentiation and maturation of dendritic cells for therapeutic use |
Country Status (10)
Country | Link |
---|---|
US (1) | US20210139852A1 (fr) |
EP (1) | EP3810757A1 (fr) |
JP (1) | JP7397493B2 (fr) |
KR (1) | KR20210024038A (fr) |
CN (1) | CN112313328A (fr) |
AU (1) | AU2019289973A1 (fr) |
CA (1) | CA3100931A1 (fr) |
IL (1) | IL279480A (fr) |
SG (1) | SG11202011806WA (fr) |
WO (1) | WO2019243537A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102346167B1 (ko) * | 2021-06-29 | 2022-01-03 | (주)더스탠다드 | 전기화학적 작용을 유도하는 고주파 비가역적 전기천공 시스템의 펄스 인가 방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10041515A1 (de) | 2000-08-24 | 2002-03-14 | Gerold Schuler | Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen |
EP1806395A1 (fr) | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation de céllules dendritiques |
CN106471004A (zh) | 2014-02-28 | 2017-03-01 | 麦吉尔大学学术发展皇家学院 | 作为用于免疫疗法的apc活化剂的tc‑ptp抑制剂 |
DK3394247T3 (da) | 2015-12-23 | 2021-04-12 | Medigene Immunotherapies Gmbh | Ny generering af antigen-specifikke tcr'er |
-
2019
- 2019-06-20 JP JP2020570762A patent/JP7397493B2/ja active Active
- 2019-06-20 AU AU2019289973A patent/AU2019289973A1/en active Pending
- 2019-06-20 CA CA3100931A patent/CA3100931A1/fr active Pending
- 2019-06-20 EP EP19740485.8A patent/EP3810757A1/fr active Pending
- 2019-06-20 WO PCT/EP2019/066398 patent/WO2019243537A1/fr active Application Filing
- 2019-06-20 US US17/253,886 patent/US20210139852A1/en active Pending
- 2019-06-20 SG SG11202011806WA patent/SG11202011806WA/en unknown
- 2019-06-20 KR KR1020217001761A patent/KR20210024038A/ko active Search and Examination
- 2019-06-20 CN CN201980041843.7A patent/CN112313328A/zh active Pending
-
2020
- 2020-12-16 IL IL279480A patent/IL279480A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2021527674A (ja) | 2021-10-14 |
JP7397493B2 (ja) | 2023-12-13 |
CN112313328A (zh) | 2021-02-02 |
KR20210024038A (ko) | 2021-03-04 |
WO2019243537A9 (fr) | 2024-02-22 |
IL279480A (en) | 2021-01-31 |
WO2019243537A1 (fr) | 2019-12-26 |
AU2019289973A1 (en) | 2020-12-03 |
EP3810757A1 (fr) | 2021-04-28 |
CA3100931A1 (fr) | 2019-12-26 |
US20210139852A1 (en) | 2021-05-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RS62975B1 (sr) | In vitro postupak za povećanje nivoa izlučivanja interleukina 2 i iz njega izvedenih proteina | |
EP3212770A4 (fr) | Procédés d'administration efficace de molécules thérapeutiques in vitro et in vivo | |
EP3487511A4 (fr) | Macrophages et monocytes autologues et allogéniques destinés à être utilisés dans des méthodes thérapeutiques | |
EP3445307A4 (fr) | Dispositif in vivo et son procédé d'utilisation | |
EP3445221A4 (fr) | Dispositif in vivo et son procédé d'utilisation | |
IL283840A (en) | Preparations for administering therapeutic substances and methods for their use and preparation | |
IL252943A0 (en) | Sunitinib formulations and methods of using them for the treatment of eye diseases | |
EP3204032A4 (fr) | Administration efficace de molécules thérapeutiques in vitro et in vivo | |
IL277965A (en) | Method for differentiation of ocular cells and use thereof | |
IL282447A (en) | Methods and preparations for healing eye cell | |
IL284125A (en) | History of quinoline for use in the treatment of inflammatory diseases | |
EP3537997A4 (fr) | Système et procédé d'administration d'agents thérapeutiques dans la cavité utérine | |
EP3784232A4 (fr) | Méthodes améliorés pour induire une régénération tissulaire et une sénolyse dans des cellules de mammifère | |
EP3946110A4 (fr) | Système et procédé pour administrer des agents thérapeutiques à la cavité utérine | |
IL275767A (en) | Compositions and methods for treating metabolic diseases | |
IL287796A (en) | Preparations and methods for the treatment of diseases mediated by ATPase | |
IL272401A (en) | A method for the production of therapeutic exosomes from nanoelectroporation and non-endocytic cellular transfections | |
ZA202100234B (en) | Methods and compositions using recombinant dendritic cells for cancer therapy | |
ZA202211512B (en) | An in vitro method for inducing the differentiation of hscs into tregs | |
EP3645020A4 (fr) | Compositions et procédés pour la thérapie cellulaire adoptive | |
IL279480A (en) | A method for in vitro differentiation and maturation of dendritic cells for therapeutic use | |
EP3648779A4 (fr) | Utilisation de lactobacilles vaginaux pour améliorer le taux de réussite de la fécondation in vitro | |
EP3708654A4 (fr) | Méthode d'induction de la différenciation en et de production d'adipocytes beiges et blancs | |
EP3645019A4 (fr) | Compositions et méthodes pour thérapie cellulaire adoptive | |
EP3495471A4 (fr) | Procédé permettant d'induire la différentiation de cellules souches pluripotentes in vitro |