SG11202010976PA - Cancer-specific t-cell receptors - Google Patents

Cancer-specific t-cell receptors

Info

Publication number
SG11202010976PA
SG11202010976PA SG11202010976PA SG11202010976PA SG11202010976PA SG 11202010976P A SG11202010976P A SG 11202010976PA SG 11202010976P A SG11202010976P A SG 11202010976PA SG 11202010976P A SG11202010976P A SG 11202010976PA SG 11202010976P A SG11202010976P A SG 11202010976PA
Authority
SG
Singapore
Prior art keywords
cancer
specific
cell receptors
receptors
cell
Prior art date
Application number
SG11202010976PA
Other languages
English (en)
Inventor
Andrew Sewell
Garry Dolton
Original Assignee
Univ College Cardiff Consultants Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ College Cardiff Consultants Ltd filed Critical Univ College Cardiff Consultants Ltd
Publication of SG11202010976PA publication Critical patent/SG11202010976PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001129—Molecules with a "CD" designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001148—Regulators of development
    • A61K39/001149—Cell cycle regulated proteins, e.g. cyclin, CDC, CDK or INK-CCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001157—Telomerase or TERT [telomerase reverse transcriptase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/00119—Melanoma antigens
    • A61K39/001191—Melan-A/MART
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11202010976PA 2018-06-25 2019-06-25 Cancer-specific t-cell receptors SG11202010976PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1810358.0A GB201810358D0 (en) 2018-06-25 2018-06-25 Cancer-specific t-cell receptors
PCT/GB2019/051785 WO2020002899A1 (en) 2018-06-25 2019-06-25 Cancer-specific t-cell receptors

Publications (1)

Publication Number Publication Date
SG11202010976PA true SG11202010976PA (en) 2021-01-28

Family

ID=63042790

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010976PA SG11202010976PA (en) 2018-06-25 2019-06-25 Cancer-specific t-cell receptors

Country Status (15)

Country Link
US (1) US12053513B2 (ko)
EP (1) EP3810175A1 (ko)
JP (1) JP2021529181A (ko)
KR (1) KR20210023822A (ko)
CN (1) CN112292392A (ko)
AU (1) AU2019295371A1 (ko)
BR (1) BR112020023182A2 (ko)
CA (1) CA3099677A1 (ko)
EA (1) EA202092861A1 (ko)
GB (1) GB201810358D0 (ko)
IL (1) IL279621A (ko)
MX (1) MX2020013601A (ko)
SG (1) SG11202010976PA (ko)
WO (1) WO2020002899A1 (ko)
ZA (1) ZA202006675B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220233662A1 (en) * 2020-12-30 2022-07-28 University College Cardiff Consultants Ltd. Novel peptide
WO2023118820A1 (en) * 2021-12-21 2023-06-29 Continuum Life Sciences Limited Cancer specific t-cell receptors
GB202211194D0 (en) 2022-08-01 2022-09-14 Univ College Cardiff Consultants Ltd Novel TCRs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567707B1 (en) * 2007-07-27 2016-10-05 Immatics Biotechnologies GmbH Composition of tumour-associated peptides and related anti-cancer vaccine
US9808504B2 (en) * 2009-09-22 2017-11-07 Yale University Immunogenic epitopes as targets for universal cancer vaccines
EP3297660A2 (en) * 2015-05-20 2018-03-28 The Broad Institute Inc. Shared neoantigens

Also Published As

Publication number Publication date
AU2019295371A1 (en) 2020-12-17
BR112020023182A2 (pt) 2021-02-09
CN112292392A (zh) 2021-01-29
CA3099677A1 (en) 2020-01-02
ZA202006675B (en) 2022-09-28
JP2021529181A (ja) 2021-10-28
WO2020002899A1 (en) 2020-01-02
US20210196807A1 (en) 2021-07-01
IL279621A (en) 2021-03-01
MX2020013601A (es) 2021-03-09
US12053513B2 (en) 2024-08-06
GB201810358D0 (en) 2018-08-08
KR20210023822A (ko) 2021-03-04
EA202092861A1 (ru) 2021-04-19
EP3810175A1 (en) 2021-04-28

Similar Documents

Publication Publication Date Title
DK3440105T3 (da) T-cellereceptorer
DK3440106T3 (da) T-cellereceptorer
DK3394094T3 (da) T-celle receptorer specifikke for ny-eso-1 tumor antigen-hla-a*02 komplekset
DK3494133T3 (da) Anti-kras-g12d-t-cellereceptorer
CA201856S (en) Access-resistant holder
IL274025A (en) A new T-cell receptor
HK1253695A1 (zh) T細胞受體特異性抗體
SG11202103609YA (en) T-cell receptors and uses thereof
EP3840066C0 (en) LIGHT-EMITTING DEVICE
GB201717974D0 (en) Modified receptors
IL279621A (en) Cancer-specific T-cell receptors
PL3512537T3 (pl) Immunoterapia limfocytami t
EP3383893A4 (en) T CELL RECEPTORS WITH VARIABLE SINGLE DOMAIN
ZA201903791B (en) Rod-mountable holder
GB201702617D0 (en) Receptor
IL275139A (en) NKG2D DARIC receptors
IL275079A (en) DARIC interleukin receptors
EP3578650A4 (en) NEW T-LYMPHOCYTE RECEPTOR
EP3857903C0 (en) DEVICE LOCATION DETERMINATION
GB201719169D0 (en) Novel T-cell receptor and ligand
EP3904374A4 (en) OBJECT MODIFIED BY A T LYMPHOCYTE RECEPTOR
GB201809544D0 (en) Mouthpiece holder
GB201806020D0 (en) Conduit
CA185363S (en) Cable holder
GB201817943D0 (en) Galanin-2 receptor agonists